Tzu-I Chen

ORCID: 0000-0003-2282-1443
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Cancer-related molecular mechanisms research
  • Lung Cancer Research Studies
  • Lung Cancer Treatments and Mutations
  • Genital Health and Disease
  • Cervical Cancer and HPV Research
  • Liver Disease and Transplantation
  • Pancreatitis Pathology and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Hepatitis B Virus Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Lung Cancer Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Alcohol Consumption and Health Effects
  • Esophageal Cancer Research and Treatment

National Yang Ming Chiao Tung University
2024-2025

Fu Jen Catholic University
2023-2024

National Health Research Institutes
2024

Asia University
2024

INTRODUCTION: The prospective study aimed to investigate the long-term associated risks of cirrhosis and hepatocellular carcinoma (HCC) across various subtypes steatotic liver disease (SLD). METHODS: We enrolled 332,175 adults who participated in a health screening program between 1997 2013. Participants were categorized into subtypes, including metabolic dysfunction-associated SLD (MASLD), MASLD with excessive alcohol consumption (MetALD), alcohol-related (ALD), based on ultrasonography...

10.14309/ajg.0000000000002778 article EN cc-by-nc-nd The American Journal of Gastroenterology 2024-03-27

Background and Aims: This large-scale, population-based cohort study examined the associations between metabolic syndrome cholangiocarcinoma risk, including its intra- extra-hepatic forms. Approach Results: A total of 4,932,211 adults aged ≥40 years participated in a government-initiated health checkup program (2012–2017), which collected lifestyle data, anthropometric measurements, biochemical tests. Follow-up continued until 2021, with data linkage to National Cancer Death Registries...

10.1097/hep.0000000000001312 article EN cc-by-nc-nd Hepatology 2025-03-21

Previous studies have indicated that HBV infection and T2DM are the factors increase risk of developing HCC. The experimental evidence has shown antiglycemic agents may reduce However, effect dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) on HCC in patients with chronic remains unclear. In this retrospective cohort study, we extracted from National Health Insurance Research Database (NHIRD) Taiwan. cases were divided into DPP-4 use non-use groups, according to whether they received...

10.3390/cancers15041148 article EN Cancers 2023-02-10

In a country with high prevalence of cigarette smoking, betel chewing, and alcohol drinking, cancers the oral cavity, nasopharynx, larynx were fourth, twelfth seventeenth leading causes cancer death, respectively, for men in 2020. We analyzed patients head neck from 1980 to 2019 Taiwan Cancer Registration Database discussed annual average percent change, age period, birth cohort. Obvious period effects are seen oral, oropharyngeal, hypopharyngeal cancer; however, most significant effect was...

10.1186/s12885-023-10651-6 article EN cc-by BMC Cancer 2023-03-06

The safety of human papillomavirus (HPV) vaccines has been evaluated continuously in pre-licensure clinical trials, post-marketing surveillance systems, and observational studies. Most studies have found no significant association between serious adverse events HPV vaccination. However, these focused on Western populations; similar focusing Asian populations are insufficient. Our retrospective cohort study used the HPV-vaccination records junior high-school adolescent girls aged 12-15 years...

10.1016/j.vaccine.2023.11.010 article EN cc-by-nc-nd Vaccine 2023-11-01
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