A5084358993- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- Electrospun Nanofibers in Biomedical Applications
- Hydrogels: synthesis, properties, applications
- RNA Interference and Gene Delivery
- Graphene and Nanomaterials Applications
- Cancer, Hypoxia, and Metabolism
- Essential Oils and Antimicrobial Activity
- Nanoplatforms for cancer theranostics
- Advanced Sensor and Energy Harvesting Materials
- Electrochemical sensors and biosensors
- Bone Tissue Engineering Materials
- Lipid Membrane Structure and Behavior
- Biosensors and Analytical Detection
- Phytochemistry and Biological Activities
- Advancements in Transdermal Drug Delivery
- Metabolomics and Mass Spectrometry Studies
- 3D Printing in Biomedical Research
- Natural product bioactivities and synthesis
- Advanced Biosensing Techniques and Applications
- MicroRNA in disease regulation
- Phytochemicals and Antioxidant Activities
- Monoclonal and Polyclonal Antibodies Research
- biodegradable polymer synthesis and properties
- Nanoparticles: synthesis and applications
Tabriz University of Medical Sciences
2016-2025
Tarbiat Modares University
2024
University of Tabriz
2015-2021
University of Maragheh
2021
K.N.Toosi University of Technology
2012
University of Guilan
2010-2011
Aim: The overexpression of miRNA-21 correlates with the cisplatin (CIS) resistance in ovarian cancers. Methods: AS1411 antinucleolin aptamer-decorated PEGylated poly(lactic-co-glycolic acid) nanoparticles containing CIS (Ap–CIS–NPs) and anti-miR-21 (Ap-anti-miR-21-NPs) were prepared, physicochemically investigated their cancer-targeting ability was confirmed. CIS-resistant A2780 cells (A2780 R) infected using Ap-anti-miR-21-NPs to decrease drug sensitize CIS. Afterward, miR-21-inhibited...
Butylated hydroxyanisole (BHA) is a synthetic phenolic food additive that used to prevent oils, fats, and shortenings from oxidative deterioration rancidity. It was tested for potential cytotoxicity genotoxicity upon A549 lung cancer cells. MTT assay flow cytometry analysis were assessment, whereas evaluated in vitro by DAPI staining, alkaline comet, DNA fragmentation assays. BHA dose- time-dependently decreased the growth of cells with an IC50 ∼0.55, 0.4, 0.3 mM at 24, 48, 72 h,...
In this study, stimuli-responsive nanofibers (NFs) were successfully prepared via electrospinning method. Poly(N-isopropylacrylamide-co-acrylamide-co-vinylpyrrolidone) P(NIPAAM-AAm-VP) was used as the material for preparing NFs. Doxorubicin (Dox)-loaded NFs and characterized by XRD, Scanning electron microscopy FTIR. A response surface methodology to evaluate effect of key parameters on fiber diameter. The cytotoxicity Dox-loaded evaluated 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium...
Lycopene belongs to the carotenoids that shows good pharmacological properties including antioxidant, anti-inflammatory and anticancer. However, as a result of very low aqueous solubility, it has limited systemic absorption, following oral administration.Here, we prepared stable lycopene-loaded solid lipid nanoparticles using Precirol® ATO5, Compritol 888 ATO myristic acid by hot homogenization method with some modification. The size morphological characteristics were evaluated Scanning...
In the past few years, research has focused on design and development of natural polymers-based hydrogels owing to their inherent features as well numerous application ranges. this context, polysaccharide-based have attracted significant interest mainly due superior physicochemical biological characteristics. However, these types biomaterials 'suffer' from some problems. This review aims give an update diverse optimization strategies used improve properties based polysaccharides for...