A5074311593- Tactile and Sensory Interactions
- Neurobiology of Language and Bilingualism
- Reading and Literacy Development
- Visual perception and processing mechanisms
- Multisensory perception and integration
- Neural dynamics and brain function
- Cognitive and developmental aspects of mathematical skills
- Vestibular and auditory disorders
- Face Recognition and Perception
- Neuroscience and Music Perception
- Hemispheric Asymmetry in Neuroscience
- EEG and Brain-Computer Interfaces
- Robotics and Automated Systems
- Hearing Impairment and Communication
- Facial Nerve Paralysis Treatment and Research
- Digital Accessibility for Disabilities
- Functional Brain Connectivity Studies
- Visual Attention and Saliency Detection
- Gaze Tracking and Assistive Technology
- Hearing, Cochlea, Tinnitus, Genetics
Beijing Normal University
2015-2025
Johns Hopkins University
2021-2024
National Institute on Drug Abuse
2024
National Institutes of Health
2024
Trinity College Dublin
2024
Institute of Psychology, Chinese Academy of Sciences
2018-2024
University of Chinese Academy of Sciences
2018-2024
Chinese Institute for Brain Research
2020
Summary Human ventral occipitotemporal cortex (vOTC) contains specialized regions that support visual recognition of behaviorally-relevant categories, including faces, written language and places (e.g., 1–4 ). An open question is how experience interacts with innate constraints to enable functional specialization. We investigate this by comparing vOTC function across sighted congenitally blind adults. In adults, a region in lateral called the fusiform face area (FFA) responds preferentially...
The cortex is organized along macroscale structural and functional gradients that extend from unimodal to transmodal association areas somatosensory visual regions. It has not been tested whether this organization represents an intrinsic neuro-architecture immune sensory experience or depends on input. Here, we conducted connectome gradient analyses using resting-state Magnetic Resonance Imaging in congenitally blind individuals sighted controls. In both groups, observed a principal (G1)...
The neural basis of reading is highly consistent across many languages and scripts. Are there alternative routes to reading? How does the sensory modality symbols (tactile vs. visual) influence their representations? We examined these questions by comparing visual print (sighted group, n = 19) tactile Braille (congenitally blind 19). Blind sighted readers were presented with written (words, consonant strings, non-letter shapes) spoken stimuli backward speech) that varied in word-likeness....
Comparisons across adults with different sensory histories (blind vs. sighted) have uncovered effects of experience on human brain function. In people born blind visual cortices are responsive to non-visual tasks and show altered functional connectivity at rest. Since almost all research has been done adults, little is known about the developmental origins this plasticity. Are infant initially functionally like those sighted blindness causes reorganization? Alternatively, do infants start...
How rigidly does innate architecture constrain function of developing cortex? What is the contribution early experience? We review insights into these questions from visual cortex in people born blind. In blindness, occipital cortices are active during auditory and tactile tasks. 'cross-modal' plasticity tells us about cortical flexibility debated. On one hand, networks blind respond to higher cognitive information, such as sentence grammar, suggesting drastic repurposing. other, line with...
The engagement of the cerebellum VI in reading was reported both typically developing and dyslexic readers. However, it is still not clear how contributes to reading. Here we have examined correlation intrinsic cerebro-cerebellar functional connectivity with two critical reading-related skills-phonological awareness (PA) rapid automatized naming (RAN)-with fMRI technology. Specifically, tested hypothesis that may contribute either by phonological skills or automatizing skills. We chose left...
Auditory phonological processing skills are critical for successful reading development in English not only native (L1) speakers but also second language (L2) learners. However, the neural deficits of auditory remain unknown English-as-the-second-language (ESL) learners with difficulties. Here we investigated responses during spoken word rhyme judgments typical and impaired ESL readers China. The showed comparable activation left superior temporal gyrus (LSTG), reduced inferior frontal...
Comparisons across adults with different sensory histories (blind vs. sighted) have uncovered effects of experience on human brain function. In people born blind visual cortices are responsive to non-visual tasks and show altered functional connectivity at rest. Since almost all research has been done adults, little is known about the developmental origins this plasticity. Are infant initially functionally like those sighted blindness causes reorganization? Alternatively, do infants start...
Abstract The neural basis of reading is highly consistent across many languages and scripts. Are there alternative routes to reading? How does the sensory modality symbols (tactile vs. visual) influence their representations? We examined these questions by comparing visual print (sighted group, n=19) tactile Braille (congenitally blind n=19). Blind sighted readers were presented with written (words, consonant strings, non-letter shapes) spoken stimuli backward speech) that varied in...
A growing body of evidence suggests that children with dyslexia in alphabetic languages exhibit visual-spatial attention deficits can obstruct reading acquisition by impairing their phonological decoding skills. However, it remains an open question whether these are present non-alphabetic languages. Chinese, its logographic writing system, offers a unique opportunity to explore this question. The presence Chinese insufficiently investigated. Therefore, study aimed such exist, employing...
The engagement of the cerebellum in reading is not unprecedented. However, it still unclear which regions are specifically involved and how processes different languages. With functional magnetic resonance imaging, we compared cerebellar neural activity Chinese child learners English between non-reading tasks to identify functionally specialized areas for reading, characters words a passive viewing paradigm detect sensitive scripts. We first focused on right lobule VI, during observed two...
Abstract Comparisons across adults with different sensory histories (blind vs. sighted) have uncovered effects of experience on human brain function. In people born blind visual cortices are responsive to non-visual tasks and show altered functional connectivity at rest. Since almost all research has been done adults, little is known about the developmental origins this plasticity. Are infant initially functionally like those sighted blindness causes reorganization? Alternatively, do infants...
The contribution of innate constraints and experience to the development face selectivity in human cortex is hotly debated. Unlike sighted, people born blind report little interaction with faces any modality. A recent study adults found preferential responses tactile over scenes objects location fusiform area (FFA) (Ratan Murty et al., 2020, PNAS). Blind also show spoken written language a similar (Kanjlia 2016, PNAS; Tian 2022, Cerebral Cortex). Does FFA develop equivalently regardless...
Abstract Many studies demonstrated that alphabetic language speaking children with developmental dyslexia had a deficit in visual-spatial attention, especially rapid orienting of the attentional spotlight. Chinese, as logographic language, is characterized highly complexity. To date, few explored attention Chinese dyslexia. The present study examined using visual search task. results showed poor performances conjunction search, indicating they attention. Meanwhile, only was significant...