A5034518585- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Urologic and reproductive health conditions
- Innovations in Medical Education
- MRI in cancer diagnosis
- Dental Education, Practice, Research
- Pediatric Urology and Nephrology Studies
- Health and Medical Research Impacts
- Diversity and Career in Medicine
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Bladder and Urothelial Cancer Treatments
- Surgical Simulation and Training
- Renal Transplantation Outcomes and Treatments
- Anatomy and Medical Technology
- Urological Disorders and Treatments
- Meta-analysis and systematic reviews
- Organ Transplantation Techniques and Outcomes
- Cancer, Lipids, and Metabolism
- Urinary Tract Infections Management
- Medical Education and Admissions
- Bee Products Chemical Analysis
- Biliary and Gastrointestinal Fistulas
- Colorectal Cancer Screening and Detection
University College London
2017-2025
Chelsea and Westminster Hospital NHS Foundation Trust
2023
West Middlesex University Hospital
2023
University Hospitals Sussex NHS Foundation Trust
2023
University College London Hospitals NHS Foundation Trust
2019-2023
Chelsea and Westminster Hospital
2023
London Postgraduate Medical and Dental Education
2019-2021
University College Hospital
2020-2021
Whittington Hospital
2020-2021
Whittington Health NHS Trust
2020-2021
All risk stratification strategies in cancer overlook a spectrum of disease. The Prostate MR Imaging Study (PROMIS) provides unique opportunity to explore cancers that are overlooked by multiparametric magnetic resonance imaging (mpMRI).To summarise attributes systematically mpMRI.PROMIS tested performance mpMRI and transrectal ultrasonography (TRUS)-guided biopsy, using 5 mm template mapping (TPM) biopsy as the reference standard.Outcomes were overall maximum Gleason scores, core length...
Abstract Background There is currently conflicting evidence surrounding the effects of obesity on postoperative outcomes. Previous studies have found to be associated with adverse events, but others no association. The aim this study was determine whether increasing body mass index (BMI) an independent risk factor for development major complications. Methods This a multicentre prospective cohort across UK and Republic Ireland. Consecutive patients undergoing elective or emergency...
The inclusion of imaging as a triage test in diagnostic guidelines for prostate cancer (PC) has introduced visible target guiding treatment allocation and disease management. Focal therapy (FT) is promising approach with low side-effect profile treating magnetic resonance (MRI)-visible PC within limited framework guideline recommendations or clinical trials. On the basis accumulated research experience, we present systematic to FT indications ablation targets that includes findings, margin...
In the United Kingdom, donation after circulatory death (DCD) kidney transplant activity has increased rapidly, but marked regional variation persists. We report how DCD influenced waitlisted outcomes for a single center. Between 2002-2003 and 2011-2012, 430 (54%) 361 (46%) brain (DBD) kidney-only transplants were performed at Cambridge Transplant Centre, with higher proportion of donors fulfilling expanded criteria status (41% vs. 32% DBD; p = 0.01). Compared U.K. outcomes, which DCD:DBD is...
Studies of non-apical progenitors (NAPs) have been largely limited to the developing mammalian cortex. They are postulated generate increase in neuron numbers that underlie brain expansion. Recently, NAPs also reported retina and central nervous system non-mammalian species; latter, however, they remain poorly characterized. Here, we characterize NAP location along zebrafish during embryonic development, determine their cellular molecular characteristics renewal capacity. We identified a...
No AccessJournal of UrologyAdult Urology1 Mar 2021Negative Prebiopsy Magnetic Resonance Imaging and Risk Significant Prostate Cancer: Baseline Long-Term Followup Results Julie Buisset, Joseph M. Norris, Philippe Puech, Xavier Leroy, Nassima Ramdane, Elodie Drumez, Arnauld Villers, Jonathan Olivier BuissetJulie Buisset Department Urology, Univ. Lille, France , NorrisJoseph Norris Division Surgery Interventional Science, University College London, UK PuechPhilippe Puech Radiology, LeroyXavier...
False positive multiparametric magnetic resonance imaging (mpMRI) phenotypes prompt unnecessary biopsies. The Prostate MRI Imaging Study (PROMIS) provides a unique opportunity to explore such in biopsy-naïve men with raised prostate-specific antigen (PSA) and suspected cancer. To compare mpMRI lesions with/without significant cancer on transperineal mapping biopsy (TPM). PROMIS participants (n = 235) underwent followed by combined procedure at University College London Hospital, including...
Abstract Objectives To describe characteristics, details of diagnosis and outcomes urogenital tuberculosis (UGTB) in a low‐prevalence country. Methods We conducted retrospective observational study 37 consecutive patients diagnosed with UGTB between 1 st January 2014 31 October 2019 an East London hospital. Results 68% (25/37) were male the median age was 42 years (IQR 34–55). 89% (33/37) born outside United Kingdom 65% (24/37) South Asian region. Renal (32.4%), epididymal (24.3%)...
Objectives: To assess the clinical outcomes of mpMRI before biopsy and evaluate space remaining for novel biomarkers. Methods: The INNOVATE study was set up to validity fluidic biomarkers in men with suspected prostate cancer who undergo pre-biopsy mpMRI. We report characteristics this cohort, distribution serum biomarkers, PSA density (PSAD), compare Likert scoring system Prostate Imaging–Reporting Data System v2.1 (PI-RADS) undergoing biopsy. Results: 340 underwent cancer. 193/340 (57%)...
Following the outbreak of novel SARS-CoV-2 (COVID-19), World Health Organization made a number recommendations regarding utilisation healthcare services. In general, there has been reduction in elective services including outpatient clinics, diagnostic and surgery. Inevitably these reductions for all but most urgent clinical work will have detrimental impact on patients, alternative ways working use telemedicine may help to mitigate this. Similarly, electronic solutions enable clinicians...
Background The effects of regional histopathologic changes on prostate MRI scans have not been accurately quantified in men with an elevated prostate-specific antigen (PSA) level and no previous biopsy. Purpose To assess how Gleason grade, maximum cancer core length (MCCL), inflammation, prostatic intraepithelial neoplasia (PIN), or atypical small acinar proliferation within a Barzell zone affects the odds visibility. Materials Methods In this secondary analysis Prostate Imaging Study...
To the Editor, Pelvi-ureteric junction obstruction (PUJO) is a well-recognised clinical entity characterised by functionally significant impairment of drainage urine at level pelvi-ureteric due to extrinsic or intrinsic and encountered both adult paediatric urologists alike. Management PUJO has been surgical historically, gold standard an open Anderson-Hynes dismembered pyeloplasty [...].