A5102907842- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Chronic Disease Management Strategies
- Orthopedic Infections and Treatments
- Peripheral Neuropathies and Disorders
- Emergency and Acute Care Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- Immune Cell Function and Interaction
- Amoebic Infections and Treatments
- Galectins and Cancer Biology
- Child Development and Digital Technology
- Pericarditis and Cardiac Tamponade
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects of Natural Compounds
- Nursing Diagnosis and Documentation
- COVID-19 diagnosis using AI
- Pancasila Values in Education
- Myasthenia Gravis and Thymoma
- Education and Character Development
- COVID-19 Clinical Research Studies
Queen Mary University of London
2018-2024
Barts Health NHS Trust
2018-2023
Royal London Hospital
2019-2021
International Centre for Diarrhoeal Disease Research
2021
Papworth Hospital NHS Foundation Trust
2017
Southend University Hospital NHS Foundation Trust
2016
Broomfield Hospital
2011
Breast tuberculosis (TB) is rare in Western Europe, and its diagnosis may be delayed through lack of awareness presenting features. Our institution serves a large East London population with high incidence TB.To characterize features avoidable diagnostic delay breast TB patients.We conducted 13-year retrospective study patients treated at our including demographic, clinical, microbiology, pathology data.Forty-seven cases were included; 44 (94%) female, median age 33 years (IQR 28.5-39.5)....
Abstract Objectives To describe characteristics, details of diagnosis and outcomes urogenital tuberculosis (UGTB) in a low‐prevalence country. Methods We conducted retrospective observational study 37 consecutive patients diagnosed with UGTB between 1 st January 2014 31 October 2019 an East London hospital. Results 68% (25/37) were male the median age was 42 years (IQR 34–55). 89% (33/37) born outside United Kingdom 65% (24/37) South Asian region. Renal (32.4%), epididymal (24.3%)...
Maintaining adherence to treatment for tuberculosis (TB) is essential if the disease be eliminated. As part of formative research develop an intervention improve adherence, we documented lived experiences adults receiving anti-TB (ATT) in three UK cities and examined how personal, social, structural circumstances interacted impact on individuals' treatment. Using a topic guide that explored social TB care, conducted in-depth interviews with 18 (six women) who were being or had been treated...
A 50-years old male presented with quadriplegia and paresthesia was diagnosed as Guillain-Barré syndrome (GBS). He found positive for severe acute respiratory coronavirus-2 (SARS-CoV-2) six weeks prior to the onset of weakness. GBS disability score 4. Electrophysiology showed inflammatory demyelinating polyradiculopathy. Anti-SARS-CoV-2 IgG positive. Immunological tests Campylobacter jejuni, Zika virus, Hepatitis E Herpes Simplex Haemophilus influanzae Mycoplasma pneumoniae were negative....
The chronic nature of Human Immunodeficiency Virus Type 1 (HIV) infection leads to the functional exhaustion HIV specific CD8+ T cells. Although multiple markers have been identified so far, recently discovered cell immunoglobulin and mucin domain 3 (TIM-3) molecules distinguishes bona fide exhausted cells with replicative senescence impairment. TIM-3 is expressed on helper type (TH1) cytotoxic (TC1) during once ligated its ligand transmits negative signaling arrest function. This effect...
This article explores the phenomenon of repeated Hajj in Indonesia through guideline Maqashid Sunnah, intending to provide a critical reinterpretation this practice. As one fundamental pillars Islam, has deep spiritual and social significance. However, trend Indonesian society raised various controversies, including social, economic, religious implications. By employing Sunnah approach, intends uncover underlying objectives Sharia behind rituals as revealed Hadiths. Furthermore, it...
<h3>Introduction and objectives</h3> Screening treatment of migrants to the UK for LTBI is a key component TB collaborative strategy in England. The London borough Newham pilot site national programme whereby care delivered entirely within primary care. We sought identify facilitators barriers delivery by understanding views healthcare professionals delivering programme. <h3>Methods</h3> Between August 2017 February 2018, questionnaires were sent all GP practices community pharmacies...
<h3>Introduction and objectives</h3> Since 2014, the London borough of Newham has been a pilot for national latent tuberculosis infection (LTBI) screening treatment programme recent migrants. Effective delivery requires collaboration between multiple stakeholders across primary secondary care; we sought to understand lessons learned from 5 years running service. <h3>Methods</h3> We performed semi-structured interviews with nine multi-level involved in implementation programme. This included...
<h3>Introduction/Objectives</h3> Public Health England 2019 report showed that extra-pulmonary tuberculosis represents over half (59.3%) of all diagnosed cases TB in the UK. Foreign-born population had almost twice as many disease (48.5%) compared with those born UK (27.8%). Aiming to improve early diagnosis east London's large migrant population, we compare baseline demographics and clinical features between UK-born foreign-born EPTB cases. <h3>Methods</h3> We conducted a retrospective...
In the UK stable patients with COPD are managed in primary care. NICE guidelines recommend specific criteria regularly assessed. <b>Method:</b> We conducted a survey of care delivered by all 50 General Practices (GPs) our catchment area. assessed compliance including frequency reviews, spirometry, smoking cessation, pharmacological treatment and side effects, long term oxygen therapy (LTOT), pulmonary rehabilitation nutrition. <b>Results:</b> 30 (60%) GPs completed survey. All reported...
COVID-19 disrupted the TB prevention programme in UK, especially for infection (TBI) care. We explore whether experience of pandemic impacted on patients' perceptions TBI and its treatment. Semi-structured interviews were conducted as part Research to Improve Detection Treatment (RID-TB) programme, exploring perceptual practical barriers Nineteen people diagnosed with interviewed between August 2020 April 2021. Recordings transcribed analysed using a constant comparative approach, allowing...
<h3>Background</h3> Emergency Department (ED) presentations could present a valuable opportunity to identify high-risk individuals with latent tuberculosis infection (LTBI) and active (TB) disease. We aimed investigate the prevalence cost-effectiveness of screening for LTBI pulmonary TB disease among migrants under-served groups attending London EDs. <h3>Methods</h3> recruited adults EDs (18/7/2013–25/5/2017) who were either recent entrants from high TB-incidence countries; or had history...
<h3>Introduction</h3> Tuberculous abscesses are rare, accounting for 1% of extra-pulmonary tuberculosis (TB). The chest wall is often a site cold abscesses. There have been only case reports described in the literature. We report series TB diagnosed large European centre. <h3>Methods</h3> A retrospective analysis at centre all cases between 2005 -2018 notified London register. <h3>Results</h3> identified 22 TB, this was 0.3% over time period. 81.8% (18/22) were male, median age 33.06 years...