A5101465845- Microtubule and mitosis dynamics
- Magnetic properties of thin films
- Cell Image Analysis Techniques
- Metamaterials and Metasurfaces Applications
- Magnetic and transport properties of perovskites and related materials
- Single-cell and spatial transcriptomics
- Supercapacitor Materials and Fabrication
- Photosynthetic Processes and Mechanisms
- Thermal Radiation and Cooling Technologies
- ZnO doping and properties
- Solar Thermal and Photovoltaic Systems
- Advancements in Battery Materials
- Molecular Biology Techniques and Applications
- Random lasers and scattering media
- Electrohydrodynamics and Fluid Dynamics
- Virus-based gene therapy research
- Photodynamic Therapy Research Studies
- Magneto-Optical Properties and Applications
- Mineral Processing and Grinding
- Internet of Things and Social Network Interactions
- Transition Metal Oxide Nanomaterials
- Bacteriophages and microbial interactions
- Advanced Antenna and Metasurface Technologies
- Topological and Geometric Data Analysis
- Orbital Angular Momentum in Optics
University of Minnesota
2022-2025
University of Wisconsin–Madison
2023-2024
Research Center for Applied Science, Academia Sinica
2021-2022
National Taiwan University
2015-2022
University of Washington
2017-2019
National Central University
2018
Yuan Ze University
2013-2015
National Sun Yat-sen University
2012
National Taiwan University of Arts
2012
National Pingtung University of Science and Technology
2011
Broadband perfect absorbers in the visible region have attracted considerable attention many fields, especially solar thermophotovoltaic and energy harvesting systems. However, developing light with high absorptivity, thermal stability, a broad bandwidth remains great challenge. Here, we theoretically experimentally demonstrate that titanium nitride metasurface absorber exhibits broadband absorption an average of more than 92% over wavelength range 400 to 750 nm. The increase is attributed...
Crystal symmetry plays an important role in the Hall effects. Unconventional spin effect (USHE), characterized by Dresselhaus and out-of-plane spins, has been observed materials with low crystal symmetry. Recently, antisymmetric planar (APHE) was discovered rutile RuO2 IrO2 (101) thin films, which also exhibit In this study, we report observation of both USHE APHE (111) using spin-torque ferromagnetic resonance harmonic measurements, respectively. Notably, unconventional efficiency from more...
Complex oxide films stabilized by epitaxial growth can exhibit large populations of point defects which have important effects on their properties. The site occupancy pulsed laser-deposited terbium iron garnet (TbIG) with excess (Tb) is analyzed, in the terbium:iron (Tb:Fe)ratio 0.86 compared to stoichiometric value 0.6. magnetic properties TbIG are sensitive occupancy, exhibiting a higher compensation temperature (by 90 K) and lower Curie 40 than bulk Tb3 Fe5 O12 garnet. Data derived from...
Abstract Super-resolution microscopy has become an indispensable tool across diverse research fields, offering unprecedented insights into biological architectures with nanometer scale resolution. Compared to traditional nanometer-scale imaging methods such as electron microscopy, super-resolution offers several advantages, including the simultaneous labeling of multiple target biomolecules high specificity and simpler sample preparation, making it accessible most researchers. In this study,...
Recent advancement in the switching of perpendicular magnetic tunnel junctions with an electric field has been a milestone for realizing ultra-low energy memory and computing devices. To integrate current spin-transfer torque-magnetic junction spin–orbit devices, typical linear fJ/V m range voltage controlled anisotropy (VCMA) needs to be significantly enhanced approaches that include new materials or stack engineering. A possible bidirectional 1.1 pJ/V VCMA effect predicted by using heavily...
Abstract Plasmonic structural color, in which vivid colors are generated via resonant nanostructures made of common plasmonic materials, such as noble metals have fueled worldwide interest backlight-free displays. However, that were withstanding ultrahigh temperatures without damage remain an unmet challenge due to the low melting point metals. Here, we report refractory hafnium nitride (HfN) crystals can generate full-visible color with a high image resolution ∼63,500 dpi while temperature...
A BIPV-powered smart window comprising a building-integrated photovoltaic (BIPV) panel and an all-solid-state electrochromic (EC) stack is proposed. In the proposed device, output voltage of BIPV varies in accordance with intensity incident light modulated such way as to generate EC required maintain indoor illuminance within specified range. Two different stacks are fabricated characterized, namely one ITO/WO(3)/Ta(2)O(5)/ITO ITO/WO(3)/lithium-polymer electrolyte/ITO. It shown that two...
Intrinsically disordered regions (IDR) and short linear motifs (SLiMs) play pivotal roles in the intricate signaling networks governed by phosphatases kinases. B56δ (encoded PPP2R5D ) is a regulatory subunit of protein phosphatase 2A (PP2A) with long IDRs that harbor substrate-mimicking SLiM multiple phosphorylation sites. De novo missense mutations cause intellectual disabilities (ID), macrocephaly, Parkinsonism, broad range neurological symptoms. Our single-particle cryo-EM structures...
Abstract The cell cycle is a fundamental process essential for proliferation, differentiation, and development. It consists of four major phases: G1, S, G2, M. These phases collectively drive the reproductive are meticulously regulated by various proteins that play critical roles in both prevention progression cancer. Traditional methods studying these functions, such as flow cytometry, require substantial number cells to ensure accuracy. In this study, we have developed user-friendly,...
ABSTRACT The cell cycle is a fundamental process essential for proliferation, differentiation and development. It consists of four major phases: G1, S, G2 M. These phases collectively drive the reproductive are meticulously regulated by various proteins that play crucial roles in both prevention progression cancer. Traditional methods studying these functions, such as flow cytometry, require substantial number cells to ensure accuracy. In this study, we have developed user-friendly...
The kinetochore, an intricate macromolecular protein complex located on chromosomes, plays a pivotal role in orchestrating chromosome segregation. It functions as versatile platform for microtubule assembly, diligently monitors binding fidelity, and acts force coupler. Comprising over 100 distinct proteins, many of which exist multiple copies, the kinetochore's composition dynamically changes throughout cell cycle, responding to specific timing conditions. This dynamicity is important...
Random laser actions in ultraviolet and visible regions have been demonstrated based on the composites consisting of bio-inspired diatom frustules. Owing to low optical loss derived from porous network structures, we report wide spectrum range random lasers arising GaN film Rh6G dye via using biological diatoms as scattering centers. Interestingly, both visible-range with very sharp peaks can be easily obtained, average length optics cavity closed size frustules cases, indicating excellent...
Abstract A new approach is proposed to light up band-edge stimulated emission arising from a semiconductor with dipole-forbidden band-gap transition. To illustrate our working principle, here we demonstrate the feasibility on composite of SnO 2 nanowires (NWs) and chicken albumen. NWs, which merely emit visible defect emission, are observed generate strong ultraviolet fluorescence centered at 387 nm assisted by albumen room temperature. In addition, stunning laser action further discovered...
In this paper we developed a new type of glass encapsulation LED module which potentially provides higher reliability at power.
Abstract Background: Microtubule-targeting agents (MTAs) have been widely utilized in cancer treatment, but the development of novel MTAs has faced limitations. CMPD1, a highly selective inhibitor MAP kinase-activated protein kinase 2 (MK2) with dual functions as microtubule inhibitor, shows promise targeted therapy for triple-negative breast (TNBC). This study aimed to investigate effects targeting MK2 and acting on cell cycle progression, dynamics, TNBC-related processes. Methods: CMPD1...
Abstract Microtubule-targeting agents (MTAs) have been successfully translated from basic research into clinical therapies and widely used as first- second-line chemotherapy drugs for various cancers. However, current MTAs exhibit positive responses only in subsets of patients are often accompanied by side effects due to their impact on normal cells. This underscores an urgent need develop novel therapeutic strategies that enhance MTA efficacy while minimizing toxicity tissues. In this...
Crystal symmetry plays an important role in the Hall effects. Unconventional spin effect (USHE), characterized by Dresselhaus and out-of-plane spins, has been observed materials with low crystal symmetry. Recently, antisymmetric planar (APHE) was discovered rutile RuO$_2$ IrO$_2$ (101) thin films, which also exhibit However, correlation between USHE APHE remains largely unexplored. In this study, we report observation of both (111) using spin-torque ferromagnetic resonance (ST-FMR) harmonic...
Microtubule-targeting agents (MTAs) have been successfully translated from basic research into clinical therapies and widely used as first- second-line chemotherapy drugs for various cancers. However, current MTAs exhibit positive responses only in subsets of patients are often accompanied by side effects due to their impact on normal cells. This underscores an urgent need develop novel therapeutic strategies that enhance MTA efficacy while minimizing toxicity tissues. In this study, we...
This study presents an overlapped subarray decomposition method to effectively simulate electrically large planar array of antennas, where the extracted subarrays can be simulated in parallel by commercial codes a distributed fashion. is relatively simple and allows one obtain reasonable result within acceptable level accuracy for engineering purpose. A plug‐in code built up using as computational engine. The characteristics this are investigated considering simulation dipole antenna via...
Influenza A virus (IAV) has caused recurrent epidemics and severe pandemics. In this study, we adapted an MS2-MCP live-cell imaging system to visualize IAV replication. reporter plasmid, pHH-PB2-vMSL, was constructed by replacing a part of the PB2-coding sequence in pHH-PB2 with encoding 24 copies stem-loop structure from bacteriophage MS2 (MSL). Binding coat protein (MCP) fused green fluorescent (GFP) MSL enabled detection vRNA as punctate signals imaging. The introduction pHH-PB2-vMSL into...
Manifold embedding algorithms map high-dimensional data down to coordinates in a much lower-dimensional space. One of the aims dimension reduction is find intrinsic that describe manifold. The returned by algorithm are abstract, and finding their physical or domain-related meaning not formalized often left domain experts. This paper studies problem recovering new low-dimensional representation an automatic, principled fashion. We propose method explain manifold as non-linear compositions...