Pierre Pasquier
- Trauma and Emergency Care Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Disaster Response and Management
- Historical and Literary Studies
- Historical and Literary Analyses
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Airway Management and Intubation Techniques
- Historical Art and Culture Studies
- Hemodynamic Monitoring and Therapy
- French Urban and Social Studies
- Traumatic Ocular and Foreign Body Injuries
- Travel-related health issues
- Animal Virus Infections Studies
- Bone fractures and treatments
- Intensive Care Unit Cognitive Disorders
- Renaissance Literature and Culture
- Blood transfusion and management
- Historical Studies and Socio-cultural Analysis
- Virology and Viral Diseases
- Blood donation and transfusion practices
- Pelvic and Acetabular Injuries
- Respiratory Support and Mechanisms
Service de Santé des Armées
2016-2025
Hôpital d'instruction des Armées Percy
2015-2024
HIA du Val-de-Grâce à Paris
2011-2024
ORCID
2024
Military Hospital
2024
Grace (United States)
2024
Hôpital Laveran
2024
Hôpital d'Instruction des Armées Sainte-Anne
2018-2024
Brigade des Sapeurs Pompiers de Paris
2021-2022
Centre National d'Études Spatiales
2022
The effects of thyrotropin-releasing hormone and 17 β-estradiol on the electrical membrane properties a prolactin-secreting pituitary cell line (GH 3 /B6) were studied with intracellular microelectrode recordings. Of cells tested, 50 percent excitable displayed calcium-dependent action potentials when depolarized. When injected directly an cell, induced within 1 minute. spiking activity was preceded by progressive increase input resistance without any detectable change in resting...
Rationale: Whether patients with coronavirus disease (COVID-19) may benefit from extracorporeal membrane oxygenation (ECMO) compared conventional invasive mechanical ventilation (IMV) remains unknown. Objectives: To estimate the effect of ECMO on 90-day mortality versus IMV only. Methods: Among 4,244 critically ill adult COVID-19 included in a multicenter cohort study, we emulated target trial comparing treatment strategies initiating no within 7 days severe acute respiratory distress...
We have studied 26 patients presenting with a symmetrical papular or papulovesicular acrolocated eruption of more than 10 days duration. Mean age at onset was 2 years (range months to 5.75 years). Lymphadenopathy noted in eight cases, and hepatomegaly one case. In 12 histopathology direct immunofluorescence were non-contributory. Cytolytic hepatitis occurred case associated HBs antigenemia. A history recent immunization given two cases. There serological evidence Epstein-Barr virus infection...
To evaluate the respective impact of standard oxygen, high-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) on oxygenation failure rate mortality in COVID-19 patients admitted to intensive care units (ICUs). Multicenter, prospective cohort study (COVID-ICU) 137 hospitals France, Belgium, Switzerland. Demographic, clinical, respiratory support, failure, survival data were collected. Oxygenation was defined as either intubation or death ICU without intubation. Variables...
Three patients with extensive necrotizing pneumonia due to Panton-Valentine leukocidin-positive Staphylococcus aureus strains and aggravating factors (leukopenia count of less than 3x10(9)/liter in all three cases hemoptysis two cases) were successfully treated toxin-suppressing agents introduced rapidly after hospital admission.
Postpartum hemorrhage is the leading cause of maternal death worldwide. Recent data from trauma patients and with hemorrhagic shock have suggested that an increased fresh frozen plasma:red blood cell (FFP:RBC) ratio may be benefit in massive bleeding. We addressed this issue cases severe postpartum hemorrhage.We reviewed all diagnosed during a 4-year period (2006-2009). Patients who were treated sulprostone required transfusion within 6 hours delivery included study divided into 2 groups...
‘ We are at war ’, French President Emmanuel Macron said in an address to the nation on 16 March 2020. As part of this national effort, Military Medical Service (FMMS) is committed fight against COVID-19. This original report aimed describe and detail actions that FMMS has carried out nationwide COVID-19 pandemic France, as well overseas. Experts field reported major conducted by during France. In just few weeks, developed ad hoc medical capabilities support health authorities. It...
French military operations in the Sahel conducted since 2013 over more than 5 million square kilometers have challenged Military Health Service with specific problems prolonged field care.To describe these challenges, we retrospectively analyzed prehospital data from first years of within a delimited area.One hundred eighty-three servicemen different nationalities were evacuated, mainly as result explosions (73.2%) or gunshots (21.9%). Their mean number evacuation was 2.2 (minimum, 1;...
Fluid administration is a first-line therapy for acute kidney injury associated with circulatory failure. Although aimed at increasing renal perfusion in these patients, this intervention may improve systemic hemodynamics without necessarily ameliorating intrarenal flow distribution or urine output. We used Doppler techniques to investigate the effects of fluid on and relationship between changes hypothesized that, compared hemodynamic variables, would better predict increase output after...
The French Military Health Service has standardized its military prehospital care policy in a ''Sauvetage au Combat'' (SC) program (Forward Combat Casualty Care). A major part of the SC training relies on simulations, which are challenging and costly when dealing with more than 80,000 soldiers. In 2014, decided to develop deploy 3D-SC1, serious game (SG) intended train assess soldiers managing early steps SC.The purpose this paper is describe creation production 3D-SC1 present deployment.A...
Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring intensive care unit (ICU) have a high incidence of hospital-acquired infections; however, data regarding hospital acquired bloodstream infections (BSI) are scarce. We aimed to investigate risk factors outcome BSI in critically ill infectious disease-19 (COVID-19) patients.We performed an ancillary analysis multicenter prospective international cohort study (COVID-ICU study) that included...
Abstract Background Delaying time to prone positioning (PP) may be associated with higher mortality in acute respiratory distress syndrome (ARDS) due coronavirus disease 2019 (COVID-19). We evaluated the use and impact of early PP on clinical outcomes intubated patients hospitalized intensive care units (ICUs) for COVID-19. Methods All ARDS COVID-19 were involved a secondary analysis from prospective multicenter cohort study COVID-ICU network including 149 ICUs across France, Belgium...
To provide guidelines to define the place of human factors in management critical situations anaesthesia and care. A committee nineteen experts from SFAR GFHS learned societies was set up. policy declaration links interest applied respected throughout guideline-producing process. Likewise, did not benefit any funding a company marketing health product (drug or medical device). The followed GRADE® method (Grading Recommendations Assessment, Development Evaluation) assess quality evidence on...
Limitations of life-sustaining therapies (LST) practices are frequent and vary among intensive care units (ICUs). However, scarce data were available during the COVID-19 pandemic when ICUs under intense pressure. We aimed to investigate prevalence, cumulative incidence, timing, modalities, factors associated with LST decisions in critically ill patients. did an ancillary analysis European multicentre COVID-ICU study, which collected from 163 France, Belgium Switzerland. ICU load, a parameter...
To reduce the number of deaths caused by exsanguination, initial management severe trauma aims to prevent, if not limit, lethal triad, which consists acidosis, coagulopathy, and hypothermia. Recently, several studies have suggested adding hypocalcemia triad form diamond, but evidence supporting this change is limited. Therefore, aim study was compare diamond for their respective associations with 24-h mortality in patients receiving transfusion. We performed a multicenter retrospective...