- Fungal and yeast genetics research
- Alcoholism and Thiamine Deficiency
- Bioinformatics and Genomic Networks
- Microtubule and mitosis dynamics
- Plant Micronutrient Interactions and Effects
- Biochemical Acid Research Studies
- Polyamine Metabolism and Applications
- Iron Metabolism and Disorders
- Endoplasmic Reticulum Stress and Disease
- Metabolism and Genetic Disorders
- Microbial Metabolic Engineering and Bioproduction
- Reproductive Biology and Fertility
- Urological Disorders and Treatments
- Sperm and Testicular Function
- Mitochondrial Function and Pathology
- Trace Elements in Health
- Ubiquitin and proteasome pathways
- Vitamin C and Antioxidants Research
Istanbul University
2018-2022
Alanya Hamdullah Emin Pasa University
2018
Alanya Alaaddin Keykubat Üniversitesi
2018
Thiamine diphosphate (ThDP) is an essential cofactor for important enzymes in carbohydrate, amino acid and lipid metabolisms. It also known that thiamine plays role stress response of some organisms. In this study, we focused on the effect responses triggered by various agents. For purpose, firstly, viability Schizosaccharomyces pombe cell cultures was examined under oxidative, osmotic heat stresses. The highest tolerance observed due to presence extracellular (1.5 µM) found only against...
Thiamine is a major vitamin that acts as cofactor in energy metabolism all organisms, well lipid and amino acid metabolisms, associated with many diseases. It known glucose starvation decreases the intracellular thiamine pool while increasing oxidative stress tolerance. Earlier, whole genome analysis, we detected differences expression of genes related to pathway against Schizosaccharomyces pombe. We investigated effects repression S. pombe by comparing some encoding key enzymes each at...
This study focuses on the effect of iron hexose transporters which perform glucose uptake. For this aim, we investigated role in utilization and expression Schizosaccharomyces pombe . We applied different concentrations (1, 2, 5, 10 mM) to cells grown up mid‐logarithmic phase. According analysis cell viability morphology, determined 2 mM 5 as non‐toxic toxic doses, respectively. Besides, consumption efficiency increased (1.5‐fold) were exposed these concentrations. qRT‐PCR transporter genes...
The aim of the study was to investigate efficiency ram seminal plasma and fetal calf serum on freezing buck semen. Twenty ejaculates were collected using an electro-ejaculator split into six groups. While FCS additive not used in A1, A2 A3 groups, 10% added B1, B2 B3 These groups then edited according whether or SP involved. design done as follows: Group A1 (control 1), group without SP, containing instead SP. Groups B1 2), forms these Progressive sperm motility percentages found be higher...
Complex human diseases such as metabolic disorders, cancer, neurodegenerative diseases, and mitochondrial dysfunctions arise from the biochemical or genetic defects in various cellular processes. Therefore, it is important to understand which processes are affected by impairment. Because genome-wide screening of mutant collections (haploid/diploid deletion library) provides clues for understanding conserved biological finding potential target genes, we screened haploid collection...
Glucose is both the favourite carbon and energy source acts as a hormone that plays regulating role in many biological processes. Calorie restriction extends lifespan organisms, including Schizosaccharomyces pombe, while uptake of high glucose leads to undesired results, such diabetes aging. In this study, sequence analysis pombe ird5 ird11 mutants was performed using next-generation sequencing techniques total 20 different mutations were detected. resistant oxidative stress without calorie...