- RNA Interference and Gene Delivery
- Lipid Membrane Structure and Behavior
- Electrocatalysts for Energy Conversion
- DNA and Nucleic Acid Chemistry
- Catalytic Processes in Materials Science
- Gold and Silver Nanoparticles Synthesis and Applications
- Surfactants and Colloidal Systems
- Orbital Angular Momentum in Optics
- Smart Agriculture and AI
- Polymer Surface Interaction Studies
- Water Quality Monitoring Technologies
- Electrochemical Analysis and Applications
- Microfluidic and Bio-sensing Technologies
- Advanced biosensing and bioanalysis techniques
- Electrostatics and Colloid Interactions
- Thin-Film Transistor Technologies
- Organic Electronics and Photovoltaics
- Advancements in Battery Materials
- Fish biology, ecology, and behavior
- Supramolecular Self-Assembly in Materials
- Nanopore and Nanochannel Transport Studies
- Semiconductor materials and interfaces
- Theoretical and Computational Physics
- Nanocluster Synthesis and Applications
- Electrohydrodynamics and Fluid Dynamics
National Synchrotron Radiation Research Center
2017-2024
National Cheng Kung University
2001-2023
National Tsing Hua University
2012-2019
Kaohsiung Medical University
2015
Abstract Cutaneous wounds are prompt to be contaminated by bacteria, but the clinical benefits of applying antibiotics and antiseptics in wound management have not been proven. Statins 3‐hydroxy‐3‐methylglutaryl‐coenzyme A ( HMG‐CoA ) reductase inhibitors commonly used lower cholesterol levels. Studies indicated that statins, especially simvastatin, promote healing experimental models. As Staphylococcus aureus is one most important microorganism responsible for infections, aims this study...
This study provides new evidence on a long postulated mechanism of phase separation in polymer/fullerene mixture during spin coating for controlled nanodomains oriented crystallization and heterojunctions that favor applications polymer solar cells (PSCs). The simultaneous nanoscale the are traced using situ grazing‐incidence small‐ wide‐angle X‐ray scattering. Combined with complimentary results from time‐resolved optical reflectance spectroscopy, transient stratification liquid film...
Cationic lipid–DNA (CL–DNA) complexes can be used as non-viral vectors to improve transfection efficiency in gene therapy. It is greatly desirable develop new ways of packing DNA order make breakthroughs on the development highly efficient delivery systems. Different from widely-studied vesicle based CL–DNA complexes, we have developed a novel cationic bicelle–DNA complex system by mixing bicelles with form alternating stacks disc bilayered plates and arrays repeat distance 7.5 nm. SAXS TEM...
The nucleation and growth process of gold supercrystals in a surfactant diffusion approach is followed by simultaneous small- wide-angle X-ray scattering (SAXS/WAXS), supplemented with scanning electron microscopy. results indicate that supercrystal can be activated efficiently upon placing concentrated solution nematic phase on top nanocrystal droplet trapped the middle vertically oriented capillary tube. Supercrystal nuclei comprised tens nanocubes are observed nearly instantaneously...
Conventional gas sensors work upon changes in mechanical or conductive properties of sensing materials during a chemical process, which may limit availabilities size miniaturization and design simplification. However, fabrication miniaturized with superior sensitivities real-time label-free probing reactions catalytic processes remains highly challenging, particular regard to integration into desired smaller volume without losing the recyclability properties. Here, we demonstrate unique...
Disc-shaped bicelles are formed by mixing long-chain lipids with short-chain at suitable molar ratios and they have a relatively uniform size, typically around few tens of nanometers in diameter. Different from the formulated cationic or anionic liposome–DNA complexes, which used as nonviral vectors for improving transfection efficiency gene therapy, novel way packing DNA can be developed using much smaller disc-like bicelles. We demonstrate that lipid bicelle-ion–DNA (AB–DNA) complexes help...
Computer vision has been applied in many fields recently to extract useful information from images. One such application is the monitoring of various aquaculture species increase production. By locations and quantities white shrimp, farmers could deliver feed more precisely. Besides, about length shrimp make estimate delivery time accurately. Usually, ensure accuracy computer vision, a relatively high-quality picture required. However, quality underwater photography easily influenced by...
We demonstrated that the reactivity, electrochemically active area (ECSA), and long-term structural stability of Pt-based core–shell nanoparticles (NPs) under methanol oxidation reaction (MOR) can be controlled by crystal structure chemical composition core. This approach is inspired relaxation shell Pt atoms on two types crystalline cores (e.g., Ru Co) due to differences in surface free energy between facets. Due isotropic facet Co cores, initial formation kinetic control when thickness...
The absorption of 700 bp DNA by a charged diblock copolymer monolayer at the air–water (D2O) interface was investigated surface pressure measurements and neutron reflectometry. amphiphilic PS-P4VPQ with molecular weights 19 600 12 000, respectively, formed stable interface, PS blocks in highly packed layer surface, dense P4VPQ brush adjacent to loose extending into aqueous subphase. Most segments were distributed only 7% contained layer. Neutron reflectometry revealed that distinct two-layer...
Atomic-scale gold clusters were intercalated at the inter-facet corner sites of Pt-shell Ru-core nanocatalysts with near-monolayer shell thickness. We demonstrated that these unique could serve as a drain valence electrons in kink region core-shell heterojunction. As jointly revealed by density functional theory calculations and band spectra, Au extract core-level to band. They prevent corrosion due protonation enhance tolerance CO increasing electronegativity outermost surface NCs during...
Langmuir–Blodgett monolayers of thiolated gold nanoparticles mixed with dipalmitoylphosphatidylcholine/sodium dodecyl sulfate (DPPC/SDS) were investigated by combining the X-ray reflectivity, grazing-incident scattering, and TEM analyses to reveal in-depth in-plane organization 2D morphology such monolayers. It was found that addition a charged single-tail surfactant Au nanoparticle monolayer helps stabilize strengthen mechanical property film. For mixing lipids, it could be pushed on top...
Acoustic levitation is considered one of the most effective noncontact particle manipulation methods, along with aerodynamic, ferromagnetic, and optical techniques. It not restricted by material properties target. However, existing acoustic techniques have some drawbacks that limit their potential applications. Therefore, in this article, an innovative approach proposed to manipulate objects more intuitively freely. By taking advantage transition periods between pulse trains electrical...
Time-resolved small-angle X-ray scattering was applied to study charged lipid exchange between oppositely disc-shaped bicelles. The of lipids gradually reduces the surface charge density and weakens electrostatic attraction bicelles which form alternately stacked aggregates upon mixing. Initially, at a high with almost no free water layer bicelles, fast kinetics dominate process. At later stage lower larger gap slow take over. are correlated close contact when there is tightly bound time...
We demonstrate that the lamella-forming polystyrene-block-poly(N-methyl-4-vinylpyridinium iodine) (PS-b-P4VPQ), with similar sizes of PS and P4VPQ blocks, can be dispersed in aqueous solutions by forming lipid/PS-b-P4VPQ multilamellae. Using small-angle neutron scattering (SANS) 1,2-dipalmitoyl-d62-sn-glycero-3-phosphocholine (d62-DPPC) D2O, a broad correlation peak is found profile signifies formation loosely ordered d62-DPPC/PS-b-P4VPQ The thicknesses hydrophobic hydrophilic layers...
Sn dopants undergo restructuring into Ti sites of TiO<sub>2</sub> upon lithiation reaction. These attract Li to form local SnLi<sub>x</sub> alloys, which sufficiently increase the capacity Sn-substituted as a negative electrode material.
In the case of short incubation times, Pt atoms are directly distributed atop core crystal. For long a PtRu alloyed layer forms prior to deposition shell crystal in Ru core–PtRu alloy–Pt rich NCs.
The impact of additives on the nanoscale structures spin-cast polymer composite films, particularly in solar cells, is a topic significant interest. This study focuses blend film comprising poly(thieno[3,4- b ]thiophene- alt -benzodithiophene) (PTB7) and [6,6]-phenyl-C 71 -butyric acid methyl ester (PC BM), exploring how like 1,8-diiodooctane (DIO) influence from chlorobenzene solution. Combined results specular X-ray neutron reflectivity, grazing-incidence small- wide-angle scattering...
Time-resolved, grazing incidence small- and wide-angle X-ray scattering together with in situ UV-Vis reflectance spectroscopy unveil the surface layering early stage of spin-coating a polymer-fullerene mixture, which drives surface-down local phase separation over flow- to evaporation-dominated stages film formation for mutually confined intercalated nanodomains polymer crystallites fullerene aggregates. This is reported by Chun-Jen Su, U-Ser Jeng, co-workers article number 1601842.
The rising of smart aquaculture offers the possibility to maintain or even increase production shrimps with less cost and environmental impact. most critical factors that affect growth rate shrimp is efficiency feeding. Therefore, identify location number are important for optimizing feeding approach. Recently, computer vision has been applied in many fields extract useful information from images. To cost, also used monitor products aquaculture. Usually, ensure accuracy vision, a relatively...
Among many non-contact particle manipulation methods, acoustic levitation (AL) is most popular since it not restricted by the characteristics of target material. However, existing AL's structures still have some disadvantages which limited their potential further applications. Take application twin tweezer for example, complex calculations make them difficult to be commercialized. Therefore, in this paper, an innovative method proposed implement AL more intuitively and freely. Through...