A5083670170- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatitis Pathology and Treatment
- Minimally Invasive Surgical Techniques
- DNA and Nucleic Acid Chemistry
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Cells and Metastasis
- Surgical Sutures and Adhesives
- Neuroendocrine Tumor Research Advances
- Pediatric Hepatobiliary Diseases and Treatments
- Renal cell carcinoma treatment
- Surgical Simulation and Training
- RNA Research and Splicing
- Cancer Genomics and Diagnostics
- Peptidase Inhibition and Analysis
- Bacterial Genetics and Biotechnology
- Liver Disease Diagnosis and Treatment
Pohang University of Science and Technology
2020
Seoul National University Hospital
2016-2018
Seoul National University
2017
Objective: This study was performed to determine whether neoadjuvant treatment increases survival in patients with BRPC. Summary Background Data: Despite many promising retrospective data on the effect of for borderline resectable pancreatic cancer (BRPC), no high-level evidence exists support role such treatment. Methods: phase 2/3 multicenter randomized controlled trial designed enroll 110 BRPC who were randomly assigned gemcitabine-based chemoradiation (54 Gray external beam radiation)...
Our previous randomized controlled trial revealed no difference in 2-year overall survival (OS) between extended and standard resection for pancreatic adenocarcinoma. The present study evaluated the 5-year OS recurrence patterns according to extent of pancreatectomy.Between 2006 2009, 169 consecutive patients were prospectively enrolled (n = 83) or 86) groups compare rate, long-term factors associated with survival.The surgical R0 rate was similar (85.5 vs. 90.7%, P 0.300). Five-year (18.4...
The use of preoperative biliary drainage (PBD) for managing patients with periampullary cancer awaiting surgery remains controversial. impact PBD status and type on surgical outcomes has not been established, leading to a lack consensus. We aimed evaluate the short-term in curatively resected cancer.We retrospectively reviewed data from undergoing curative resection. A propensity score-matched analysis was performed adjust clinical differences. Univariate multivariate analyses were determine...
Increasing surgical expertise in minimally invasive surgery has allowed laparoscopic to be performed many abdominal surgeries. Laparoscopic choledochal cyst excision and Roux-en-Y hepaticojejunostomy are challenging sophisticated surgeries because of the difficult anastomosis. Recent advances robotic have enabled more delicate precise movements, Endowrist instruments allow for securing sutures during This study aimed compare outcomes excision.Sixty-seven patients who underwent or...
False Positive Diagnosis of Hepatocellular Carcinoma in Liver Resection PatientsThe diagnosis hepatocellular carcinoma (HCC) is based on imaging studies particularly high-risk patients without histologic confirmation.This study evaluated the prevalence and characteristics false-positively diagnosed HCC a liver resection cohort for HCC.A retrospective review was performed 837 cases clinically between 2005 2010 at our institute.High-risk with tumors > 1 cm one or two image findings consistent...
The current robotic platform overcomes some limitations of single-incision laparoscopic cholecystectomy (SILC), however, whether surgery is a safe and feasible approach must be investigated.Patients referred for elective willing to undergo (SIRC) by consent were enrolled. All procedures performed the same team using surgical equipment.Thirty patients underwent SIRC. mean overall operation time was 53.80 ± 15.20 min (range 32-80) console 16.67 5.63 11-30). postoperative stay 1.30 0.54 days...
ABSTRACT Here, we quantitatively evaluate the accuracy of protein–DNA interactions in AMBER and CHARMM force fields by comparing experimental simulated diffusion coefficients proliferating cell nuclear antigen (PCNA). We find that both underestimate at least an order magnitude because between basic amino acids DNA phosphate groups are too attractive. Then, propose Lennard-Jones parameters optimized using osmotic pressure data model chemicals, which one can reproduce coefficients. Newly will...