A5059229896- Mosquito-borne diseases and control
- Parasitic Diseases Research and Treatment
- Virology and Viral Diseases
- Parasite Biology and Host Interactions
- Viral Infections and Vectors
- Parasites and Host Interactions
- HIV/AIDS Research and Interventions
- Cytomegalovirus and herpesvirus research
- Reproductive tract infections research
- Hepatitis B Virus Studies
- Syphilis Diagnosis and Treatment
- T-cell and Retrovirus Studies
- Mycobacterium research and diagnosis
- Insect symbiosis and bacterial influences
- Infectious Diseases and Tuberculosis
- Vector-Borne Animal Diseases
- Herpesvirus Infections and Treatments
- Leprosy Research and Treatment
- Sex work and related issues
- Hepatitis Viruses Studies and Epidemiology
Fundação de Amparo à Pesquisa do Estado do Amazonas
2024
Fundação Oswaldo Cruz
2013-2018
Universidade Federal do Amazonas
2013
Leoni (Germany)
2013
Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas
2003
ABSTRACT The Brazilian western Amazon region is currently experiencing its largest laboratory confirmed Oropouche virus (OROV) outbreak, with nearly 6,000 reported cases in the states of Amazonas (AM), Acre (AC), Rondônia (RO), and Roraima (RR), between August 2022 March 2024. Here, we sequenced analyzed 382 full-length OROV genomes from human samples collected 2024 all four states, aiming to trace origin genetic evolution leading current outbreak. Genomic analyses revealed that recent...
Infection with Zika virus (ZIKV) manifests in a broad spectrum of disease ranging from mild illness to severe neurological complications and little is known about immunopathogenesis.To define the immunologic biomarkers that correlate acute ZIKV infection.We characterized levels circulating cytokines, chemokines, growth factors 54 infected patients both genders at five different time points after symptom onset using microbeads multiplex immunoassay; comparison 100 age-matched controls was...
Objectives To determine the etiology and factors associated with genital ulcer disease (GUD) among patients presenting to a sexually transmitted infections clinic in Manaus, Brazil; compare multiplex polymerase chain reaction (M-PCR) assay for diagnosis of GUD standard methods. Methods Ulcer swabs were collected used Tzanck test processed an M-PCR detect herpes simplex virus (HSV-1/2), Treponema pallidum (T. pallidum), Haemophilus ducreyi (H. ducreyi). Sera tested HIV syphilis antibodies....
Mansonella ozzardi is a poorly understood human filarial parasite with broad distribution throughout Latin America. Most of what known about its parasitism has come from epidemiological studies that have estimated incidence using light microscopy. Light microscopy can, however, miss lighter, submicroscopic, infections. In this study we compared M. estimates made microscopy, PCR. 214 DNA extracts Large Volume Venous Blood Samples (LVVBS) were taken volunteers two sites in the Rio Solimões...
The aim of this study was to investigate sensitivity disorders in the oral cavity related presence Mycobacterium leprae saliva treatment-naïve patients with leprosy state Amazonas, Brazil. A cross-sectional conducted involving 45 subjects leprosy. were interviewed evaluate cavity. For detection M. leprae, and slit-skin smear samples collected. analysed using a bacteriological index (BI) protocol real-time quantitative polymerase chain reaction (qPCR). results indicated that 15 (33.3%) showed...
Mansonellosis is endemic in several regions of Africa, the Caribbean, and Latin America. Mansonella ozzardi perstans have been reported America, including Amazon region. A morphological molecular microfilariae study was performed Pauini (Brazil). Blood samples were collected from 40 individuals, analyzed by Giemsa-stained blood film two different nested polymerase chain reactions which detect internal transcribed spacer-1 major sperm protein gene. By microscopy, 14 positive: 11 as M. three...
A infecção pelo vírus da hepatite B (VHB) constitui um importante problema de Saúde Pública na Amazônia brasileira, onde a exposição precoce, durante infância, ocorre em áreas maior endemicidade.Com finalidade contribuir para as políticas regionais controle do VHB região, foi conduzido inquérito prevalência marcadores sorológicos e moleculares entre 1.460 gestantes atendidas Programa Pré-Natal, nas nove sub-regiões Estado Amazonas, Brasil.Entre essas subregiões, antígeno superfície (HBsAg)...
Abstract Infection with Zika virus (ZIKV) manifests in a broad spectrum of disease ranging from mild illness to severe neurological complications. To define immunologic correlates ZIKV infection, we characterized the levels circulating cytokines, chemokines and growth factors 54 infected patients both genders, at five different time-points after symptoms onset using microbeads multiplex immunoassay; statistical analysis data mining compared 100 age-matched controls. ZIKV-infected present...