A5045463362- Salivary Gland Disorders and Functions
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Neuroscience of respiration and sleep
- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Biochemical effects in animals
- Stress Responses and Cortisol
- Urinary Bladder and Prostate Research
- Pain Mechanisms and Treatments
- Neurological Disorders and Treatments
- Neuroendocrine regulation and behavior
- Circadian rhythm and melatonin
- Polyamine Metabolism and Applications
- Hypothalamic control of reproductive hormones
- Neuroscience and Neuropharmacology Research
- Amino Acid Enzymes and Metabolism
- Cannabis and Cannabinoid Research
- Oral microbiology and periodontitis research
- Axon Guidance and Neuronal Signaling
- Botulinum Toxin and Related Neurological Disorders
- S100 Proteins and Annexins
- Nicotinic Acetylcholine Receptors Study
- Salivary Gland Tumors Diagnosis and Treatment
- Regulation of Appetite and Obesity
University of Gothenburg
2012-2024
University of Alabama at Birmingham
2023
University of Cagliari
2010-2018
Lund University
1984-2012
Public Dental Service Västra Götaland
1998
New York University Press
1991-1995
Harvard University Press
1995
University of Cambridge
1995
Chitose Institute of Science and Technology
1994-1995
La Jolla Alcohol Research
1994
In the rat parotid gland, an atropine-resistant parasympathetic-nerve-evoked secretion was demonstrated in vivo. absence of atropine, non-adrenergic, non-cholinergic transmitter release seemed to contribute fluid and be largely responsible for amylase acinar secretory granules. The gland reached by nerve fibers containing substance P (SP), vasoactive intestinal peptide (VIP), and, some extent, calcitonin-gene-related (CGRP) via parasympathetic auriculo-temporal nerve. Upon electrical...
Vasoactive intestinal peptide (VIP) injected intravenously was found to induce a flow of saliva from both the parotid and submaxillary gland in rat. The secretion slow onset. amount secreted less than that gland. Parotid very viscous. VIP‐evoked more protein rich response other sialagogue drugs including β‐adrenergic receptor agonist isoprenaline. effect VIP direct; it occurred after removal adrenals, degeneration intraglandular nerves presence autonomic blockers. A supersensitivity...
The sensitivity of the rat parotid gland to chemical agents was examined 2–3 weeks after either parasympathetic denervation or sympathetic decentralization. parasympathetically denervated markedly sensitized towards methacholine; a nonspecific supersensitivity mainly mediated via α‐adrenoceptors also demonstrated. sympathetically had developed which both pre‐and postjunctional type; it predominantly former type noradrena‐line and adrenaline, entirely so phenylephrine; latter isoprene‐line,...
Substance P, a putative neurotransmitter in mammals, and physalaemin, present the skin of an amphibian, are both undecapeptides belong to family tachykinins. The secretory effect these tachykinins on parotid submaxillary glands rat was examined. Dose‐response curves showed that unoperated maximal responses were obtained intravenous dose 5–10μg/kg tachykinins, amount saliva secreted from gland twice gland, physalaemin more potent than substance P. Parasympathetic denervation decentralization...
When rats are fed on dry, cellulose rich diet the choline acetyltransferase activity of parotid gland increases, provided auriculo‐temporal nerve is intact. Dryness oral mucosa produced by atropinization also followed an increase in enzyme gland. It suggested that increased acetylcholine‐synthesizing due to enhanced traffic secretory impulses para‐sympathetic nerves gland, reflexly elicited two kinds treatment.
Abstract The influence of bladder outflow obstruction on the peripheral nervous control detrusor was investigated in female rats. performed by means partial urethral ligation. exogenously applied drugs and electrical field stimulation after for 6 weeks. content noradrenaline choline acetyltransferase also determined as well density alpha‐adrenoceptors. A significant decrease contractile response to alpha‐adrenoceptor found obstructed bladders when compared normal controls. Also...
Objective The aim was to examine the association between drug treatment and unstimulated stimulated whole saliva in four 70‐year‐old Swedish cohorts, 1971 2001. Background Both diseases their medication can affect salivary secretion rate. Materials methods study based on selected samples of cohorts born 1901/1902, 1906/1907, 1911/1912 1930/1931, respectively, a total 1072 individuals. response rate varied 65% 85%. Results mean value for higher men (1.3 ± 0.8 ml/min) than women (1.0 0.7 ( p...
The long‐term influence of substance P (SP) and vasoactive intestinal peptide (VIP) on rat salivary gland weight was investigated after parasympathetic denervation or feeding soft food. parotid lost about one‐third its within 4–5 days following postganglionic change in dietary regimen, from pellets to liquid diet, thought reduce nerve reflex activity. Daily i.v. infusions with SP VIP diminished largely prevented the fall weight, whereas pentagastrin, bethanechol saline had no effect. were...
Secretion of parotid and submandibular saliva evoked by electrical stimulation the parasympathetic nerves occurred in presence adrenergic cholinergic blocking agents. The ‘atropine‐resistant’ response amounted to about 30% gland 5% as compared before administration antimuscarinic secretion was found at relatively high frequencies, latency between start onset long. Upon long‐lasting decreased rapidly markedly. tachykinins substance P (SP) K, injected i.v., flow from both glands. Given singly,...