A5013377787- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Hepatitis Viruses Studies and Epidemiology
- Viral Infections and Outbreaks Research
- SARS-CoV-2 detection and testing
- Antibiotic Resistance in Bacteria
- Vaccine Coverage and Hesitancy
- Urinary Tract Infections Management
- Malaria Research and Control
- COVID-19 diagnosis using AI
- Vibrio bacteria research studies
- Reproductive tract infections research
- COVID-19 epidemiological studies
- Escherichia coli research studies
- COVID-19 Clinical Research Studies
- Computational Drug Discovery Methods
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV, Drug Use, Sexual Risk
- Animal Virus Infections Studies
- Antibiotic Use and Resistance
- Blood groups and transfusion
- Research on Leishmaniasis Studies
Institute of Health Research, Epidemiological Surveillance and Training
2017-2025
Cheikh Anta Diop University
2015-2024
National University Hospital
2022-2023
Hôpital Aristide Le Dantec
2008-2023
Institut Pasteur de Dakar
2023
Méditerranée Infection Foundation
2023
Centre Hospitalier National Universitaire de Fann
2022
International Livestock Research Institute
2022
Environment and Development Action Third World
2019-2021
Pharmac
2018
ABSTRACT Hepatitis B virus (HBV) infection is a leading cause of death in sub-Saharan Africa (SSA). Point-of-care tests for hepatitis surface antigen (HBsAg) could be an ideal tool large-scale HBV screening/treatment program SSA. Using data from the PROLIFICA (Prevention Liver Fibrosis and Cancer Africa) program, we conducted cross-sectional study to assess diagnostic accuracy three point-of-care (Determine, Vikia, Espline) detection HBsAg field or laboratory setting Gambia. In field, used...
Abstract The aim of this study was to determine hepatitis co‐infection in a cohort HIV infected patients at their inclusion the Senegalese Initiative ART Access. B, C, and D Hepatitis viruses serological markers were checked retrospectively on 363 stored plasma. For HBV, Abbott laboratories equipment IMx used detect HBs Ag anti Core Ab negative samples. HDV, Delta performed using Murex Kit all positive HCV, HCV detected by as double screening test confirmed INNO‐LIA TM Innogenetics...
Introduction: Genital mycoplasmas, which cause infections of the lower reproductive tract in women, are a major morbidity and complications. The aim this study was to determine prevalence mycoplasma antibiotic susceptibility profile among women Dakar. Material methods: We conducted retrospective descriptive over four-year period, from 02 January 2018 31 December 2021. population consisted referred microbiology laboratory at Military Hospital Ouakam for genital testing. Mycoplasma IES kit...
ABSTRACT Acute respiratory infections (ARI) are a health priority, especially in countries with limited resources. They major cause of morbidity and mortality, among children the elderly. In Senegal, endemic circulation viruses other than influenza has been demonstrated. However, there is paucity data exploring genetic diversity these based on whole‐genome sequencing. this study, we present under 15 years old including an overview different pathogens detected. Between November 2022 2023,...
Detailed knowledge about hepatitis B virus (HBV) vaccination coverage and timeliness for sub-Saharan Africa is scarce. We used data from a community-based cross-sectional survey conducted in 2018–2019 the area of Niakhar, Senegal, to estimate coverage, timeliness, factors associated with non-adherence World Health Organisation-recommended schedules children born 2016 (year birth dose (BD) introduction Senegal) 2017–2018. Vaccination status was assessed cards, surveillance data, healthcare...
Introduction: hepatitis B virus (HBV) infection is highly endemic in Senegal. HBV vaccine of all children has been introduced 1999 and included the Expanded Programme on Immunization 2004. The aim this study was to assess prevalence immunity status against amongst
The study aimed to estimate the prevalence of Hepatitis B virus (HBV) infection and describe HBV virological profiles among Senegalese HIV-1-infected patients. We conducted a retrospective between 2006 2010 patients from antiretroviral therapy cohort. Samples were screened using Determine(®) HBsAg or MONOLISA(®) POC test. positivity status was confirmed by Architect(®) HBsAg. Detection HBeAg, anti-HBe Ab, DNA load done for HBsAg-positive samples. Then, Anti-HBcAb tested HBsAg-negative...
Senegal introduced the infant hepatitis B virus (HBV) vaccination in 2004 and recently committed to eliminating by 2030. Updated epidemiological data are needed provide information on progress being made develop new interventions. We estimated prevalence of surface antigen (HBsAg) children adults living rural assessed treatment eligibility. A cross‐sectional population‐based serosurvey HBsAg was conducted 2018‐2019 a large sample (n = 3,118) residents Niakhar area (Fatick region, Senegal)....
Strategies to implement HBV screening and treatment are critical achieve elimination but have been inadequately evaluated in sub-Saharan Africa (sSA).
We used whole genome sequencing to identify and analyze mutations in SARS-CoV-2 urban settings during the deadliest wave of COVID-19 epidemic—from March April 2021—in Senegal. Nasopharyngeal samples testing positive for were sequenced on Illumina NovaSeq 6000 system using COVIDSeq protocol. A total 291 genotypable consensus sequences obtained. Phylogenetic analyses grouped genomes into 16 distinct PANGOLIN lineages. The major lineage was B.1.1.420, despite circulation Alpha variant concern...
In response to increasing resistance anti-malarial drugs, Senegal adopted artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria in 2006. However, of Plasmodium falciparum parasites artemisinin derivatives, characterized by delayed parasite clearance after with ACT or artesunate monotherapy, has recently emerged and rapidly spread Southeast Asia. After 10 years stability rates ranging from 5.6 11.8%, prevalence reduced susceptibility vitro...
Chronic hepatitis is a major public health problem. Hepatitis B virus the primary cause, and C together are responsible for 60% of cirrhosis 80% hepatocellular carcinomas. This study measured prevalence HBsAg among Senegalese military to develop an appropriate strategy prevent carcinoma.We conducted descriptive cross-sectional aged 25 60 years. A sample 1224 participants was selected following two-level-stratification. The mark surface HBs antigen using chemiluminescence concerned 1195...
The coronavirus disease 2019 (COVID-19) is a contagious caused by new called SARS-CoV-2. first case was discovered in Wuhan, China, December 2019, raising concerns about the emergence of that poses significant public health risk. objective this study, based on data collected and sequenced at Institut de Recherche en Santé, Surveillance Epidémiologique et Formations (IRESSEF), to characterize pandemic evolution, establish relationship between different strains each wave, finally determine...
Hepatitis B is a major public health problem in Senegal, country with high prevalence and transmission occurring mainly during infancy. Only, one 6-8 weeks vaccination campaign was initiated 2005 it part of the expanded program immunization. The aim this study to determine HBsAg children born from HIV-seropositive mothers by using dried blood specimens. Specimens were collected between July 2007 November 2012 aged 2-48 Dakar decentralized sites working on HIV mother-to-child prevention....
Hepatitis B virus (HBV) classification comprises up to 10 genotypes with specific geographical distribution worldwide, further subdivided into 40 subgenotypes, which have different impacts on liver disease outcome. Though extensively studied, the of subgenotype A sequences remains ambiguous. This study aimed characterize HBV isolates from West African patients and propose a more advanced A. Fourteen full-length genome isolated The Gambia Senegal were obtained phylogenetically analyzed....
•Omicron variant continues to progress in Senegal with the appearance of new contaminations.•IRESSEF detected first positive case Omicron on Friday, December 3, 2021.•Since this date, number infections has increased over weeks.•Molecular surveillance is carried out real time inform medical authorities.
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages that carry mutations in the spike gene are concern for potential impact to treatment and prevention efforts. To monitor new SARS-CoV-2 mutations, a panel specimens were sequenced from both wave one (N = 96), two 117) pandemic Senegal by whole genome next generation sequencing. Amongst these genomes, combinations identified, with E484K + N501T, L452R N501Y, L452M S477N exclusively found second specimens....
Background: The emergence and spread of carbapenem-resistant Acinetobacter baumannii are critical in hospitals, particularly intensive care units (ICUs), which represents a public health concern worldwide. In this study, we investigated the molecular epidemiology multi-drug resistant A. (MDR-AB) Dakar, Senegal.
 Methods. was isolated from Eosin Methylene Blue Agar culture identified using API 20NE strip test MALDI-TOF. antimicrobial susceptibility testing performed disk diffusion...
Abstract Background Although mother-to-child transmission (MTCT) of hepatitis B virus (HBV) is prevalent in West Africa, epidemiological data on HBV infection women remain scarce. We studied i) surface antigen (HBsAg) prevalence and its correlates, ii) screening history serological status awareness, iii) MTCT risk treatment needs Senegalese women. Methods A cross-sectional population-based serosurvey for HBsAg positivity was conducted 2018–2019 the rural area Niakhar (Fatick region,...