A5047839783- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Hepatitis B Virus Studies
- HIV/AIDS Impact and Responses
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Hepatitis C virus research
- Global Maternal and Child Health
- HIV/AIDS drug development and treatment
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Healthcare Systems and Reforms
- Vaccine Coverage and Hesitancy
- French Literature and Critical Theory
- Healthcare Systems and Practices
- HIV-related health complications and treatments
- Cultural Insights and Digital Impacts
- Viral Infections and Outbreaks Research
- Diverse Cultural and Historical Studies
- French Urban and Social Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- dental development and anomalies
- Dental Radiography and Imaging
- Linguistics and Discourse Analysis
- Oral microbiology and periodontitis research
Inserm
2016-2025
Institut de Recherche pour le Développement
2016-2025
Economic & Social Sciences, Health Systems & Medical Informatics
2016-2025
Aix-Marseille Université
2012-2024
Central Hospital of Yaoundé
2011-2024
Université de Montpellier
2011-2023
Agropolis International
2023
Université de Dschang
2023
Université Paris Cité
2005-2023
Hôpital Émile-Roux
2023
An efavirenz-based regimen (with a 600-mg dose of efavirenz, known as EFV600) was the World Health Organization preferred first-line treatment for human immunodeficiency virus type 1 (HIV-1) infection until June 2018. Given concerns about side effects, dolutegravir-based and low-dose efavirenz–based combinations have been considered treatments HIV-1 in resource-limited settings.
Antiretroviral therapy (ART) suppresses HIV viral load in all body compartments and so limits the risk of transmission. It has been suggested that ART not only contributes to preventing transmission at individual but potentially also population level. This trial aims evaluate effect initiated immediately after identification/diagnosis HIV-infected individuals, regardless CD4 count, on incidence surrounding population. The primary outcome overall will be over two years. Secondary outcomes...
Clinical trials of direct oral anticoagulants (DOAC) are scarce and inconclusive in patients who receiving dialysis, for whom DOAC not labelled Europe. In a French nationwide registry study on chronic we compared the effectiveness safety off-label use vs approved vitamin K antagonist (VKA).
The independent evaluation of the Cameroonian antiretroviral therapy (ART) Programme, which reached one highest coverage in eligible HIV-infected population (58%) Sub-Saharan Africa, offered opportunity to assess ART outcomes context decentralization HIV care delivery.A cross-sectional survey (EVAL, ANRS 12-116, 2007) was carried out a random sample 3151 HIV-positive patients (response rate 90%) attending 27 treatment centres at different level healthcare delivery (central, provincial and...
Prompt uptake of antiretroviral treatment (ART) is essential to ensure the success universal test and treat (UTT) strategies prevent HIV transmission in high-prevalence settings. We describe ART initiation rates associated factors within an ongoing UTT cluster-randomized trial rural South Africa. HIV-positive individuals were offered immediate intervention arm vs. national guidelines recommended (CD4≤350 cells/mm(3)) control arm. used data collected up July 2015 among ART-eligible linked...
Expanding health insurance is viewed as a core strategy for achieving universal coverage. In Senegal, in many other developing countries, this has been implemented by creating community-based (CBHI) schemes with voluntary enrolment and fixed premium paid enrollees. Yet little known about how the individuals' experience of CBHI further influences their willingness to pay (WTP). paper, we test existence reinforcement effect between effective WTP analysing mutual relationship. We rely on...
Introduction Mother-to-child transmission (MTCT) of HIV, syphilis, and hepatitis B virus (HBV) commonly observed in the WHO African region is associated with excess morbidity mortality. Despite some progress, coverage interventions to prevent MTCT these infections remains insufficient, particularly for syphilis HBV. To fulfil gaps achieve triple elimination by 2030, World Health Organization (WHO) advocates integration prevention (PMTCT) activities HBV HIV antenatal services. In partnership...
Seventy-six compounds of biological interest for the diagnosis inherited disorders amino acids (AA) metabolism have previously been demonstrated to be detectable in positive mode electrospray ionisation tandem mass spectrometry (ESI-MS/MS), after separation by ion-pairing reversed-phase liquid chromatography (RPLC). The method used tridecafluoroheptanoic acid as agent, and a gradient acetonitrile elution most retained compounds. This had suitable qualitative many AA disorders, quantitative...
Objective To assess the extent to which user fees for antiretroviral therapy (ART) represent a financial barrier access ART among HIV-positive patients in Yaoundé, Cameroon.Methods Sociodemographic, economic and clinical data were collected from random sample of 707 followed up six public hospitals capital city (Yaoundé) its surroundings through face-to-face interviews carried out by trained interviewers independently medical staff questionnaires filled prescribing physicians.Logistic...
Summary Objective To identify correlates of self‐reported antiretroviral therapies (ART) interruptions among people living with HIV and AIDS (PLWHA) in Cameroon. Methods Analyses were based on data collected the national survey EVAL (ANRS 12‐116) 533 ART‐treated PLWHA Yaoundé, capital city Cameroon, its neighbourhood. Logistic regression models used to factors associated ART longer than two consecutive days during previous 4 weeks. Results reported by 68 patients (12.8%). After adjustment...
Objectives The emergence of HIV drug resistance is a crucial issue in A frica, where second‐line antiretroviral therapy ( ART ) limited, expensive and complex. We assessed the association between adherence patterns over time, using an measure that distinguishes low from treatment interruptions, rural C ameroon. Methods performed cohort study among patients receiving nonnucleoside reverse transcriptase inhibitor NNRTI )‐based nine district hospitals, data S tratall trial (2006−2010)....
Evidence of gender differences in antiretroviral treatment (ART) outcomes sub-Saharan Africa is conflicting. Our objective was to assess (1) adherence ART and (2) virologic failure, immune reconstitution, mortality, disease progression adjusting for adherence.
To document patients' and healthcare professionals' (HCP) experiences with hepatitis B virus (HBV) C (HCV) diagnosis care, as well consequences of these infections on life trajectories in Cameroon, an endemic country sub-Saharan Africa.Qualitative sociological study combining in-depth interviews observations medical consultations. Interviews transcripts were thematically analysed according to the following themes: circumstances perceptions surrounding screening, counselling disclosure,...
Background: Intimate partner violence in its various forms increases HIV exposure female victims and potentially jeopardizes the treatment cascade, for instance, by impeding engagement adherence to care. Elevated rates of intimate are reported Central Africa. Evidence on effect antiviral therapy interruption is lacking Cameroon, where only 330,000 women live with 19% HIV-positive people virally suppressed. This study aimed assess prevalence factors against relationship antiretroviral ⩾1...
Abstract Background Data on human immunodeficiency virus (HIV) seroconversion among men who have sex with (MSM) using pre-exposure prophylaxis (PrEP) in West Africa are needed. This study aimed to document HIV and associated determinants, PrEP adherence, plasma drug concentrations, resistance MSM event-driven or daily Burkina Faso, Côte d’Ivoire, Mali, Togo. Methods A prospective cohort was conducted 2017–2021 HIV-seronegative aged 18 over were at high risk of infection. Participants could...