A5038576509- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Retinal and Macular Surgery
- Traumatic Ocular and Foreign Body Injuries
- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- Facial Trauma and Fracture Management
- Corneal surgery and disorders
- CNS Lymphoma Diagnosis and Treatment
- Optical Coherence Tomography Applications
- Infectious Diseases and Mycology
- Lymphoma Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Image Processing Techniques and Applications
- Bacterial Identification and Susceptibility Testing
- Systemic Lupus Erythematosus Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Ocular Oncology and Treatments
- Digital Imaging for Blood Diseases
- Cytomegalovirus and herpesvirus research
- Visual perception and processing mechanisms
Shantou University
2018-2025
Chinese University of Hong Kong
2014-2025
Eye Center
2021
Abstract Retinal fundus diseases can lead to irreversible visual impairment without timely diagnoses and appropriate treatments. Single disease-based deep learning algorithms had been developed for the detection of diabetic retinopathy, age-related macular degeneration, glaucoma. Here, we a platform (DLP) capable detecting multiple common referable conditions (39 classes) by using 249,620 images marked with 275,543 labels from heterogenous sources. Our DLP achieved frequency-weighted average...
To investigate the utility of metagenomic next-generation sequencing (mNGS) in identifying pathogens endophthalmitis.In this prospective study, 36 cases endophthalmitis were recruited. All patients received surgical treatment and intraocular drug lavage. The samples vitreous or aqueous humor extracted for mNGS microbiological culture. diagnostic performance was compared between culture.The positive rates culture 88.89% (32/36) 27.78% (10/36), respectively. There a statistically significant...
Vitreoretinal lymphoma (VRL) remains a diagnostic challenge due to its scarce prevalence, and delayed diagnosis usually results in blindness even fatal outcomes. Herein, an artificial intelligence (AI) system is developed identify VRL among 16 retinal diseases conditions on optical coherence tomography (OCT) images with the cross‐subject meta‐transfer learning (CS‐MTL) algorithm. Extensive experiments of few‐shot recognition tasks prove robustness our model 1‐, 3‐, 5‐shot scenarios,...
This study aimed to investigate the visual and anatomic outcomes of recombinant tissue plasminogen activator (rt-PA)-assisted vitreoretinal surgery for open globe injury (OGI) with suprachoroidal hemorrhage (SCH) identify prognostic factors. A total 94 eyes (94 patients) OGI SCH received rt-PA injection, followed by drainage on next day. The patients' demographic information, characteristics injury, anatomical were recorded. Multivariate regression analysis was performed factors less than...
Abstract Purpose This study was conducted to evaluate the prevalence and related factors of peripheral posterior pole retinal changes in highly myopic Chinese children adolescents. Methods A hospital-based cross-sectional designed. total 120 subjects with high myopia were recruited underwent cycloplegic refraction, dilated fundus examination, optical coherence tomography. statistical analysis performed associated changes. Results The mean spherical equivalent refraction − 8.74 ± 2.86 D, age...
Purpose: To evaluate the outcomes and prognostic factors of pars plana vitrectomy (PPV) combined with subretinal injection recombinant tissue plasminogen activator (rt-PA) for submacular hemorrhage (SMH) patients or without vitreous hemorrhage. Methods: Sixty-four eyes 64 SMH underwent PPV rt-PA. Best-corrected visual acuity (BCVA), displacement, postoperative complications were analyzed. Predictive final BCVA determined using multivariant linear regression. Results: There 26 VH 38...
Purpose: To report a case of iris tumor secondary to Talaromyces marneffei infection in patient with AIDS and syphilis.Case report: A 25-year-old man presented gradual vision decrease the right eye for 2 months. Ocular examination revealed best-corrected visual acuity (BCVA) 0.12 vascularized solid at inferotemporal base eye. There were some papulonecrotic skin lesions. Both serum treponema pallidum particle agglutination human immunodeficiency virus antibody positive. Non-target metagenome...
Purpose To quantitatively compare reflectivity and other morphological changes of the photoreceptors normal eyes with amblyopic using longitudinal reflectance profile (LRP) on swept-source optical coherence tomography (SS-OCT) images in children adolescents unilateral high myopia. The relationships between OCT parameters visual acuity were investigated.Method Twenty-six amblyopes myopia 34 age-, axial length- spherical equivalent-matched controls recruited. All participants underwent SS-OCT...
Inability to express the confidence level and detect unseen classes has limited clinical implementation of artificial intelligence in real-world. We developed a foundation model with uncertainty estimation (FMUE) 11 retinal conditions on optical coherence tomography (OCT). In internal test set, FMUE achieved higher F1 score 96.76% than two state-of-the-art algorithms, RETFound UIOS, got further improvement thresholding strategy 98.44%. external sets obtained from other OCT devices, an...
<title>Abstract</title> <bold>Purpose</bold> To quantitatively investigate the reflectivity and structure of outer retinal layers in children with hyperopic anisometropic amblyopia using swept-source optical coherence tomography (SS-OCT). <bold>Methods</bold> Seventy-eight patients 64 age-matched normal vision were included this study. All participants underwent SS-OCT detailed ophthalmic examinations. Longitudinal reflectance profile measurements (LRP) measured by Image J. The was at three...
Purpose. To quantitatively investigate the reflectivity and structure of outer retinal layers in children with hyperopic anisometropic amblyopia by using swept-source optical coherence tomography (SS-OCT). Methods: Seventy-eight patients 64 age-matched normal vision were included this study. All participants underwent SS-OCT detailed ophthalmic examinations. Longitudinal reflectance profile measurements measured Image J. The was at three selected positions: subfovea, 1 mm nasal to fovea,...
Inability to express the confidence level and detect unseen disease classes limits clinical implementation of artificial intelligence in real world. We develop a foundation model with uncertainty estimation (FMUE) 16 retinal conditions on optical coherence tomography (OCT). In internal test set, FMUE achieves higher F1 score 95.74% than other state-of-the-art algorithms (92.03%-93.66%) improves 97.44% threshold strategy. The similar excellent performance two external sets from same different...
Joint Shantou International Eye Center, University and the Chinese of Hong Kong, Shantou, China. Reprint requests: Haoyu Chen, MD, North Dongxia Road, Guangdong, China 515041; e-mail: [email protected] Supported by Science Technology Program (200629165261641) 2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant (2020LKSFG14B). None authors has any conflicting interests to disclose. The T. Shi H. Xie contributed equally manuscript. Concept design (H.C.), manufacture device (T.S.,...
Abstract Background This study aims to identify the risk factors in peripheral retinal changes (PRC) associated with high myopes among children and adolescents. Methods is a cross-sectional on adolescents diagnosed myopia. The subjects involved underwent series of ocular examinations, including dilated fundus examination for PRC swept-source optical coherence tomography foveal retinal, choroidal scleral thickness measurement. Then, variables were compared eyes risk, low no PRC. Spearman...
Abstract Purpose: To determine the prevalence and factors associated with peripheral posterior pole retinal changes in highly myopic Chinese children adolescents. Methods: A prospective, consecutive case series cross-sectional study was designed. One-hundred-and-twenty subjects high myopia were recruited underwent cycloplegic refraction, dilated fundus examination, optical coherence tomography. Statistical analysis performed to evaluate development of changes. Results: The mean spherical...