A5016829130- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Respiratory Support and Mechanisms
- Parasites and Host Interactions
- Parasitic infections in humans and animals
- Trypanosoma species research and implications
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Chemokine receptors and signaling
- Pancreatitis Pathology and Treatment
- COVID-19 and Mental Health
- Adrenal Hormones and Disorders
- Parasitic Infections and Diagnostics
- Fibromyalgia and Chronic Fatigue Syndrome Research
Institut Català de la Salut
2021-2022
Universitat Rovira i Virgili
2016-2019
The cytokine signature present in COVID-19 could provide information on the pathogenic mechanisms of disease and identify possible prognostic biomarkers therapeutic targets. In this longitudinal work, we studied clinical biochemical parameters circulating levels 146 patients at time admission for 4-6 weeks later. main objective study was to determine whether basal cytokines be early COVID-19, also analyze impact comorbidities, such as obesity or metabolic syndrome (MS), profile. most...
Long COVID (LC) syndrome is a complex multiorgan symptom that persists beyond >12 weeks after SARS-CoV-2 infection. The most frequently associated fatigue. Physical activity and exercise are recommended, although specific studies lacking. objectives of the present work to analyze impact supervised program on clinical evolution LC with fatigue patients identify whether certain circulating biomarkers could predict response rehabilitation. rehabilitation treatment was analyzed in 14 women...
BackgroundThe underlying mechanisms of incomplete immune reconstitution in treated HIV-positive patients are very complex and may be multifactorial, but perturbation chemokine secretion could play a key role CD4+ T-cell turnover.MethodsWe evaluated the circulating baseline 48-week follow-up concentrations SDF-1/CXCL12, fractalkine/CX3CL1, MCP-1/CCL2, MIP-α/CCL3, MIP-β/CCL4 RANTES/CCL5, we estimated their association with CXCL12, CX3CR1, CCR2, CCL5 CCR5 single nucleotide polymorphisms (SNPs)...
In SARS-CoV-2-infected patients, obesity, hypertension, and diabetes are dangerous factors that may result in death. Priority detection specific therapies for these patients necessary. We wanted to investigate the impact of obesity metabolic syndrome (MS) on clinical course COVID-19 whether prognostic biomarkers described useful predict evolution with or MS. This prospective cohort study included 303 hospitalized COVID-19. Participants were first classified according presence obesity; then,...
Abstract A relationship between polymorphisms in genes encoding interleukin 7 (IL-7) and its cellular receptor (IL-7R) antiretroviral therapy (ART)-associated immune recovery HIV subjects has been previously reported. However, details of this remain unclear, the association these with circulating IL-7/IL-7R levels is scarce. Here, we explored whether axis was associated quantitative CD4 + T-cell HIV-infected subjects. were assessed by genotyping, multiple inheritance models used to estimate...
Background: The underlying mechanisms of incomplete immune reconstitution in treated HIV-infected patients are very complex and may be multifactorial, but perturbation chemokine secretion could play a key role CD4+ T-cell turnover.Methods: We evaluated the circulating baseline 48-week follow-up concentrations SDF-1/CXCL12, fractalkine/CX3CL1, MCP-1/CCL2, MIP-a/CCL3, MIP-b/CCL4 RANTES/CCL5, we estimated their association with CXCL12, CX3CR1, CCR2, CCL5 CCR5 single nucleotide polymorphisms...