A5065359272- Wound Healing and Treatments
- Orthopaedic implants and arthroplasty
- Protease and Inhibitor Mechanisms
- Laser Applications in Dentistry and Medicine
- biodegradable polymer synthesis and properties
- Orthopedic Infections and Treatments
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Inflammatory mediators and NSAID effects
- Dermatologic Treatments and Research
- Polymer Surface Interaction Studies
- Silk-based biomaterials and applications
- Bone health and treatments
- Total Knee Arthroplasty Outcomes
- Tendon Structure and Treatment
- Cell death mechanisms and regulation
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Medical and Biological Ozone Research
- Immunotherapy and Immune Responses
- Cell Adhesion Molecules Research
- Vitamin D Research Studies
- Periodontal Regeneration and Treatments
- Peptidase Inhibition and Analysis
- RNA Interference and Gene Delivery
- Phagocytosis and Immune Regulation
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2015-2024
University of Milan
2024
Piedmont University
2013-2021
Active Technologies (Italy)
2016
CTO Hospital
2005
Ospedale G.B. Morgagni - L.Pierantoni
2002
University of Urbino
1993-1999
University of Washington
1995
University of Modena and Reggio Emilia
1995
Istituto di Farmacologia Traslazionale
1994
In recent years, bioprinting has attracted much attention as a potential tool for generating complex 3D biological constructs capable of mimicking the native tissue microenvironment and promoting physiologically relevant cell–cell cell–matrix interactions. The aim present study was to develop crosslinked printable hydrogel based on biocompatible natural polymers, gelatin xanthan gum at different percentages be used both scaffold cell growth wound dressing. CellInk Inkredible printer printing...
Hypertrophic scars resulting from severe burns are usually treated by continuous elastic compression. Although pressure therapy reaches success rates of 60-85% its mechanisms action still poorly understood. In this study, apoptosis induction and release interleukin-1beta (IL-1beta) tumor necrosis factor-alpha (TNF-alpha) were evaluated in normal (n = 3) hypertrophic (=7) after vitro mechanical the absence compression (basal condition) apoptotic cells, scored using terminal...
Abstract Organically modified mesoporous silica nanoparticles (MSNs) containing rose bengal (RB), a xanthene dye, were successfully synthesized. RB‐modified MSNs have shown relevant photostability and high efficiency in the photoproduction delivery of singlet oxygen ( 1 O 2 ), which is particularly promising for photodynamic therapy (PDT) applications. In vitro tests evidenced that RB‐MSNs are able to reduce cell proliferation one most aggressive skin cancer types (SK‐MEL‐28) after...
Human skin hosts a variety of microbes that can be transferred to surfaces ("touch microbiome"). These microorganisms considered as forensic markers similarly "touch DNA". With this pilot study, we wanted evaluate the transferability and persistence microbiome" on surface after deposition fingerprint its exposure for 30 days at room temperature. Eleven volunteers were enrolled in study. Skin microbiome samples collected by swabbing palm their hands; additionally, donors asked touch glass...
Breast cancer (BC) survivors treated with aromatase inhibitors (AIs) commonly show several pathological issues, including poor oral health, bone health impairment, and vitamin D deficiency. However, to date, issues in BC AIs have been poorly investigated their relationship deficiency are far from being understood. This study aimed evaluate the correlation between status undergoing treatment through a machine learning approach. In this cross-sectional study, we included post-menopausal women...
NETosis is a neutrophil-mediated defense mechanism during which DNA and enzymes are extruded forming network (NETs) trapping killing different pathogens. reduced in both mice humans aging.We explored the difference efficacy of NETs released elderly (> 65 years) versus adults (20-50 subjects inhibiting Staphylococcus aureus growth activating keratinocytes.Neutrophil granulocytes, obtained from venous blood healthy adult subjects, were stimulated by LPS (0-250 µg/ml) to induce formation NET....
A novel luminescent polyhedral oligomeric silsesquioxane (POSS) containing in the structure a fluorescein derivative molecule and carboxylic functionality, suitable to anchor different organic compounds (dyes, markers, drugs, contrast agents, …), was successfully synthesized characterized this manuscript by multidisciplinary approach. An emission enhancement of dye ca. four times found after reaction with POSS, rendering new hybrid compound promising agent for optical imaging. In vitro tests...
The human oral microbiome has primarily been studied in clinical settings and for medical purposes. More recently, microbial research incorporated into other areas of study. In forensics, aimed to exploit the variation composition answer forensic relevant topics, such as identification geographical provenience. Several studies have focused on use continental, national, or ethnic origin evaluations. However, it is not clear how varies between similar populations across different regions a...
Abstract An atmospheric pressure plasma deposition for P(d, L )LA (PLA) film was used to modify polymer surface properties using 1,2‐diaminopropane and acrylic acid as precursors. These two different coatings result in a high density of amino groups (PLA‐NH 2 ) carboxylic (PLA‐COOH) onto PLA demonstrated by Fourier transform infra‐red (FTIR) spectroscopy X‐ray photoelectron (XPS). Plasma modified wettability proteins adsorption from fetal bovine serum (FBS), influencing cell adhesion...
Background/Aims: The 1α,25-dihydroxycholecalciferol (Vit. D) induces eNOS dependent nitric oxide (NO) production in human umbilical vein endothelial cells (HUVEC). To our knowledge, there are no reports directly relating Vit. D induced NO to proliferation and/or migration (EC). aim of this study was evaluate whether addition porcine EC could affect their a three-dimensional matrix via production. Materials and Methods: Porcine aortic (PAE) were used effects on cell matrix. Results: PAE...