Esraa Refaat

ORCID: 0000-0003-2425-0824
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Natural product bioactivities and synthesis
  • Bioactive natural compounds
  • Phytochemical compounds biological activities
  • Anesthesia and Neurotoxicity Research
  • Advances in Cucurbitaceae Research
  • Tissue Engineering and Regenerative Medicine
  • Graphene and Nanomaterials Applications
  • Bioactive Compounds and Antitumor Agents
  • Plant-Derived Bioactive Compounds
  • Genomic variations and chromosomal abnormalities
  • Congenital heart defects research
  • Nanoparticles: synthesis and applications
  • Natural Antidiabetic Agents Studies
  • Traditional and Medicinal Uses of Annonaceae
  • Morinda citrifolia extract uses
  • Microbial Metabolites in Food Biotechnology

National Research Centre
2019-2023

Alexandria University
2019

Casuarina equisetifolia bark is rich in various active metabolites and selected to be studied due limitation of the synthetic antioxidants that have adverse side effects. The present study aimed enhance efficiency most effective extract by incorporating gold nanoparticles (Au-NPs).The phytochemical biological measurements were carried out total methanolic its successive fractions. Moreover, these assayed after Au-NPs.The revealed exhibited highest cytotoxic activities as compared other...

10.31557/apjcp.2022.23.10.3457 article EN cc-by Asian Pacific Journal of Cancer Prevention 2022-10-01

Cancer disease is regarded as one of the most significant public health issues, regardless economic standards. Medicinal plants are now a natural source anticancer medicines due to their antioxidant and anti-mutagenic actions. Cucurbitaceae considered be economically families. One family species Citrullus colocynthis (L.), which has high concentration many active secondary chemical metabolites. Various C. plant extracts showed cytotoxicity against some cancer cells. This study aims identify...

10.1038/s41598-023-46867-6 article EN cc-by Scientific Reports 2023-11-16

Potential of Casimiroa edulis and Glycosmis pentaphylla leaves extracts were investigated against the effect two different particle sizes silver nanoparticles induced toxicity in mice. Mice received (AgNPs) (100 mg/kg) with 20 100 nm for four weeks followed by daily oral dose (500 three weeks. C. identified fourteen phenolic compounds while, G. identified, twelve compounds. Additionally, biochemical, genotoxicity, mutagenicity, histopathological investigations carried out, revealed that...

10.1111/jfbc.13398 article EN Journal of Food Biochemistry 2020-08-04

During the present study, chemical compositions of protein and mucilage seeds fruits Casimiroa edulis (Llave & Lex) as well their hypoglycemic effects other related biochemical parameters were studied for first time.The content C. was prepared with 4% (w/w) yield.The amino acid analyzer hydrolysates led to identification 17 acids.Glutamic (10.25%) considered major acid.Moreover, 11% yield.GLC analysis revealed ten sugars represented (87.19%), galacturonic (31.23%) main component.Significant...

10.7324/japs.2019.91011 article EN Journal of Applied Pharmaceutical Science 2019-10-01

Rapid progress in nano-scales and nanostructure extremely altered the way of diagnosing or preventing numerous diseases. One most important nano-medicines used cancer treatment diagnosis is silver nanoparticles (AgNPs). Regardless their extensive utilization, prospective neurotoxicity wasn't studied yet. Herein, male Swiss Albino mice were intoxicated via two Nano-scales AgNPs; (20 nm 100 nm) for one month (100 mg/kg) then treated by leaves extracts both

10.1016/j.toxrep.2022.11.009 article EN cc-by Toxicology Reports 2022-01-01

We report the clinical and genetic characterization of 2 cousins sharing same chromosomal anomaly; a 22pter-q11.2 deletion 14pter-q13 duplication due to an unusual familial reciprocal non robertsonian translocation between acrocentric chromosomes t(14;22)(q13;q11.2), mother patient 1 was first cousin father 2. Fluorescent in situ hybridization confirmed cytogenetic results. The patients showed dysmorphic features developmental delay with evident intrafamilial phenotypic variability....

10.24953/turkjped.2019.05.020 article EN The Turkish Journal of Pediatrics 2019-10-25
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