A5086139129- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- Neuroscience and Neural Engineering
- Epilepsy research and treatment
- Platelet Disorders and Treatments
- Blind Source Separation Techniques
- Neurological disorders and treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Transcranial Magnetic Stimulation Studies
- Neural Networks and Applications
- Virus-based gene therapy research
- Erythrocyte Function and Pathophysiology
- Electrochemical Analysis and Applications
- Advanced MRI Techniques and Applications
- Chronic Myeloid Leukemia Treatments
- Memory and Neural Mechanisms
- Photoreceptor and optogenetics research
- Lipid metabolism and disorders
- Immune Cell Function and Interaction
- Chronic Lymphocytic Leukemia Research
- Blood groups and transfusion
- Advanced Memory and Neural Computing
- Neonatal and fetal brain pathology
Inserm
2016-2025
Université de Rennes
2016-2025
Laboratoire Traitement du Signal et de l'Image
2015-2024
Cultures et Environnements. Préhistoire, Antiquité, Moyen Âge
2010-2022
Université Côte d'Azur
2008-2022
Mines Saint-Étienne
2022
Centre Hospitalier Universitaire de Rennes
2017-2022
Aix-Marseille Université
2008-2021
Université Rennes 2
2019
Institut de Recherche en Santé, Environnement et Travail
2012-2016
This paper focuses on high-frequency (gamma band) EEG activity, the most characteristic electrophysiological pattern in focal seizures of human epilepsy. It starts with recent hypotheses about: (i) behaviour inhibitory interneurons hippocampal or neocortical networks generation gamma frequency oscillations; (ii) nonuniform alteration GABAergic inhibition experimental epilepsy (reduced dendritic and increased somatic inhibition); (iii) possible depression GABA(A,fast) circuit activity by...
The identification of brain regions generating seizures ('epileptogenic zone', EZ) in patients with refractory partial epilepsy is crucial prior to surgery. During pre-surgical evaluation, this can be performed from the analysis intracerebral EEG. In particular, presence high-frequency oscillations, often referred as 'rapid discharges', has long been recognized a characteristic electrophysiological pattern EZ. However, date, there no attempt make use specific quantitatively evaluate degree...
Erythropoietin (Epo)-producing cells were identified in the murine hypoxic kidney by situ hybridization. Profound anemia was induced order to greatly increase Epo production. This resulted high levels of mRNA kidney. 35S-labeled DNA fragments gene used as probes for Control experiments conducted parallel included kidneys nonanemic mice, RNase-treated sections, and non-Epo-related DNA. The probe gave a specific hybridization signal cortex lesser extent outer medulla. Glomerular tubular not...
The recent past years have seen a noticeable increase of interest for electroencephalography (EEG) to analyze functional connectivity through brain sources reconstructed from scalp signals. Although considerable advances been done both on the recording and analysis EEG signals, number methodological questions are still open regarding optimal way process data in order identify networks. In this paper, we impact three factors that intervene processing: i) electrodes, ii) combination between...
The human brain is a large-scale network the function of which depends on dynamic interactions between spatially distributed regions. In rapidly evolving field neuroscience, two unresolved challenges hold promise potential breakthroughs. First, functional networks should be identified using noninvasive and easy-to-use neuroimaging techniques. Second, time-space resolution these techniques good enough to assess dynamics networks. Emerging evidence suggests that electroencephalography (EEG)...
Low-voltage rapid discharges (or fast EEG ictal activity) constitute a characteristic electrophysiological pattern in focal seizures of human epilepsy. They are characterized by decrease signal voltage with marked increase frequency (typically beyond 25 Hz). have long been observed stereoelectroencephalographic (SEEG) signals recorded intra-cerebral electrodes, generally occurring at seizure onset and simultaneously involving distinct brain regions. Spectral properties as well spatial...
Loss of consciousness (LOC) is a dramatic clinical manifestation temporal lobe seizures. Its underlying mechanism could involve altered coordinated neuronal activity between the brain regions that support conscious information processing. The access hypothesis assumes existence global workspace in which becomes available via synchronized within modules, often widely distributed throughout brain. Re-entry loops and, particular, thalamo-cortical communication would be crucial to functionally...
Summary: Purpose: Several studies have demonstrated diminution in the volume of entorhinal cortex (EC) ipsilateral to pathologic side patients with temporal lobe epilepsy (TLE). The relation between degree EC atrophy and epileptogenicity this structure has never been directly studied. purpose study was determine whether evaluated by quantitative magnetic resonance imaging (MRI) method is correlated TLE. Methods: Intracerebral recordings (SEEG method) seizures from 11 mesial TLE were...