A5101505055- Ultrasound and Hyperthermia Applications
- Cardiac Imaging and Diagnostics
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Ultrasound and Cavitation Phenomena
- Ultrasound in Clinical Applications
- Coronary Interventions and Diagnostics
- Ultrasound Imaging and Elastography
- Cardiovascular Function and Risk Factors
- Acute Ischemic Stroke Management
- MRI in cancer diagnosis
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Advanced X-ray and CT Imaging
- Blood Coagulation and Thrombosis Mechanisms
- Cerebral Venous Sinus Thrombosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiovascular Effects of Exercise
- Radiation Dose and Imaging
- Bladder and Urothelial Cancer Treatments
- Tissue Engineering and Regenerative Medicine
- Central Venous Catheters and Hemodialysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Natural Products and Biological Research
University of Nebraska Medical Center
2014-2024
Shanghai Medical Information Center
2024
Zhejiang University of Water Resource and Electric Power
2023
Shanghai Ninth People's Hospital
2023
Shanghai Jiao Tong University
2023
Hebei University
2022
Mitre (United States)
2022
Nebraska Medical Center
2011-2020
Central South University
2019
Second Xiangya Hospital of Central South University
2019
We have observed a transient but significant increase in myocardial contrast intensity with intravenously injected perfluorocarbon-exposed sonicated dextrose albumin (PESDA) microbubbles that occurs on initial exposure to pulsed ultrasound (transient-response imaging). The characteristics and magnitude of this response were examined the present study.In 14 dogs, produced by transient-response imaging (TRI) was compared conventional 30-Hz (CI) after 0.005 0.030 mL/kg intravenous injection...
Background and Purpose— Destruction of microbubbles by transcutaneous low-frequency ultrasound (LFUS) has been used to lyse adjacent clot recanalize acutely thrombosed vessels. LFUS with intraarterial shown cerebral rapidly in pigs without thrombolytic drugs. We hypothesized that intravenous platelet-targeted may be a rapid noninvasive technique intracerebral Methods— After angiography, 0.5 cc autogenous thrombus was injected into 1 ascending pharyngeal artery pig, occluding it the rete...
The purpose of this study was to determine, first, whether the albumin on perfluorocarbon-exposed sonicated dextrose microbubbles has retained its known ability bind antisense oligonucleotides (DNA utilized inhibit viral replication and intimal hyperplasia). binding kinetics synthetic as well room air-containing were compared. Second, effect diagnostic ultrasound is unknown. release from also tested in vitro vivo three dogs. Synthetic exhibited much like that native but did not uniformly...
Ultrasound cavitation of microbubble contrast agents has a potential for therapeutic applications such as sonothrombolysis (STL) in acute ischemic stroke. For safety, efficacy, and reproducibility treatment, it is critical to evaluate the state (moderate oscillations, stable cavitation, inertial cavitation) activity level around treatment area. Acoustic passive detectors (PCDs) have been used this end but do not provide spatial information. This paper presents prototype 2-D imager capable...
Real-time myocardial contrast echocardiography permits the detection of perfusion abnormalities during stress echocardiography, which may improve accuracy test in detecting coronary artery stenoses. We hypothesized that this technique could be used after a bolus injection selective A2A receptor agonist regadenoson to rapidly and safely detect stenoses.In 100 patients referred for quantitative angiography, real-time was performed continuous intravenous infusion 3% Definity at baseline...
Computed tomographic coronary angiography (CTCA) has gained clinical acceptance for the detection of obstructive artery disease. Although single-center studies have demonstrated excellent accuracy, multicenter yielded variable results. The true diagnostic accuracy CTCA in "real world" remains uncertain. We conducted a field evaluation comparing multidetector with invasive CA (ICA) to understand CTCA's real-world setting.A cohort study patients awaiting ICA was between September 2006 and June...
To examine the effectiveness of 1 ‐MHz and 40‐kHz ultrasound with without microbubbles in fragmenting thrombi attenuated conditions. First, an vitro transcranial model was used to ability these frequencies fragment presence or absence perfluorocarbon‐exposed sonicated dextrose albumin microbubbles. Second, vivo transthoracic test same intravenous left circumflex coronary thrombotic occlusions. In model, both 1‐MHz ultrasonic were effective at only angiographically recanalized 4 14 occlusions...
Both early stress testing and cardiac troponin I (cTnI) measurements are useful in assessing the prognosis of patients with acute coronary syndrome (ACS). We sought to determine accuracy prognostic value wall motion analysis (WMA) myocardial perfusion (MPA) real-time contrast echocardiography (RTMCE) during dobutamine this patient population.We performed RTMCE assess 158 consecutive (mean age: 61 +/- 13 years) chest pain possible ACS. Of these, 119 had normal cTnI, while 39 isolated...
<h3>Objective</h3> We sought to determine whether guided high mechanical index (MI) impulses from a diagnostic ultrasound transducer during an intravenous microbubble infusion could augment low-dose fibrinolytic therapy in treating acute myocardial infarction (ST segment elevation infarction, STEMI). <h3>Methods</h3> Acute thrombotic occlusions of the left anterior descending were created 32 atherosclerotic pigs. Fourteen historical control pigs received half dose tissue plasminogen...