A5102799443- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Radiomics and Machine Learning in Medical Imaging
- Uterine Myomas and Treatments
- Management of metastatic bone disease
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Multiple and Secondary Primary Cancers
- Cancer Genomics and Diagnostics
- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Ectopic Pregnancy Diagnosis and Management
- Endometriosis Research and Treatment
- Prenatal Screening and Diagnostics
- Gestational Trophoblastic Disease Studies
- Syphilis Diagnosis and Treatment
- MRI in cancer diagnosis
- Intraperitoneal and Appendiceal Malignancies
- Epigenetics and DNA Methylation
- Autoimmune and Inflammatory Disorders
- Histone Deacetylase Inhibitors Research
- Prenatal Substance Exposure Effects
Centre Hospitalier Universitaire de Liège
2012-2025
University of Liège
2014-2025
Centre Hospitalier Chrétien
2015
Centre hospitalier régional de la Citadelle
1997-2003
The EORTC-55994 trial compared neoadjuvant chemotherapy (NACT) followed by radical surgery with concomitant chemoradiation (CCRT) in patients Stage IB2-IIB cervical cancer. This took almost 12 years to recruit 626 a median follow-up of 8.7 years.
Background Positron emission tomography/computed tomography (PET/CT) fails to detect approximately 25% of aortic lymph node metastasis in patients with PET/CT stage IIIC1 cervical cancer. Surgical staging could lead treatment modification and improved para-aortic distant control. Primary Objective(s) To demonstrate if chemoradiation tailored external beam radiation field based on surgical pathologic examination the is associated 3-year disease-free survival compared staged only. Study...
To evaluate efficacy and toxicity of radio-chemotherapy (RCT) MR-guided pulsed-dose-rate (PDR) adaptive brachytherapy (IGABT) for locally advanced cervical cancer (LACC).Between 2007 2014 85 patients with FIGO stage 1B1 N+ or ≥ 1B2 were treated RCT+ IGABT. The treatment consisted a pelvic± paraaortic external beam radiotherapy (EBRT) (45-50.4 Gy ± 10 boost to primary tumor and/or pathologic lymph nodes) concurrent cisplatin followed by 25-35 PDR IGABT in 30-50 pulses. ratio 3D-CFRT/IMRT was...
Promoter methylation profiles are proposed as potential prognosis and/or diagnosis biomarkers in cervical cancer. Up to now, little is known about the promoter profile and expression pattern of stem cell (SC) markers during tumor development. In this study, we were interested identify SC genes carcinogenesis. A genome-wide screening revealed a strong hypermethylation Undifferentiated Transcription Factor 1 (UTF1) cancer comparison with normal ectocervix. By direct bisulfite pyrosequencing...
To evaluate outcomes of European cross-border multidisciplinary tumor boards in terms participation, adherence to treatment recommendations, and access novel strategies.The reference network for rare gynecological tumors (EURACAN G2 domain) aims improve the diagnosis, management, patients with these cancers. Cross-border were initiated facilitate intercollegiate clinical discussions across Europe increase patients' specialist recommendations trials. All healthcare providers invited...
To evaluate the concordance between preoperative European Society for Medical Oncology (ESMO)-European of Gynaecological (ESGO)-European SocieTy Radiotherapy and (ESTRO) risk classification in early-stage endometrial cancer (EC) assessed by biopsy magnetic resonance imaging (MRI) with this based on histology surgical specimen.This bicentric retrospective study included women diagnosed EC (≤stage II) who had a complete assessment underwent management from January 2011 to December 2018....
<h3>Introduction/Background</h3> Tumour size is one of the key prognostic markers currently used to tailor type and radicality surgical treatment. Presented study aimed evaluate accuracy preoperative tumour assessment by imaging using data from SENTIX: a prospective, single-arm, international multicenter sentinel lymph node biopsy without pelvic dissection in patients with early-stage cervical cancer. <h3>Methodology</h3> Between 05/2016–09/2020, forty-seven sites across 18 countries...
<h3>Objective</h3> The aim of this study was to investigate the prognostic value metabolic parameters obtained at pretreatment [<sup>18</sup>F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ([<sup>18</sup>F]FDG PET/CT) in patients with locally advanced cervical cancer. We hypothesize that these could optimize treatment decision and thus favor outcome suffering <h3>Methods</h3> Patients cancer underwent PET/CT. Standard uptake values (maximum, mean, peak), tumor...
TPS5613 Background: Patients with medium and high-risk stage I II endometrial cancers (EC) have, despite radical surgery, a high risk for progression. Adjuvant brachytherapy or EBRT is the traditional therapy many decades although without impacting on survival. Several studies have failed to demonstrate superiority of adjuvant chemotherapy in unselected population number low-risk patients. It utmost importance efficacy combination randomized trial comparing no further treatment node negative...
Placental chorioangioma is a benign vascular tumor. Lesions larger than 4 cm may cause fetal and maternal complications. Its association with disseminated neonatal hemangiomatosis rarely described. We report case of large associated an hydrops foetalis hemangiomatosis. The relationship between placental hemangioma briefly discussed.