A5091177781- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Health and Disease Prevention
- Stroke Rehabilitation and Recovery
- Healthcare Systems and Practices
- Intracranial Aneurysms: Treatment and Complications
- Neurological Disorders and Treatments
- Climate Change and Health Impacts
- Intracerebral and Subarachnoid Hemorrhage Research
- Patient Satisfaction in Healthcare
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular and exercise physiology
- Balance, Gait, and Falls Prevention
- Action Observation and Synchronization
- Thyroid Cancer Diagnosis and Treatment
- Aging and Gerontology Research
- S100 Proteins and Annexins
- Artificial Intelligence in Healthcare
- Family and Patient Care in Intensive Care Units
- Healthcare professionals’ stress and burnout
- Antiplatelet Therapy and Cardiovascular Diseases
National Public Health Organization
2020-2022
Alexandra Hospital
2000-2020
National and Kapodistrian University of Athens
2003-2016
Imperial College Healthcare NHS Trust
2016
Charing Cross Hospital
2016
Athens State University
2006
Harvard University Press
2004
Spital Lachen
2004
University Medical Center Utrecht
1999
Eginition Hospital
1999
Among 407 New England Medical Center Posterior Circulation registry patients, 59% had strokes without transient ischemic attacks (TIAs), 24% TIAs then strokes, and 16% only TIAs. Embolism was the commonest stroke mechanism (40% of patients including cardiac origin, 14% intraarterial, 2% arterial sources). In 32% large artery occlusive lesions caused hemodynamic brain ischemia. Infarcts most often included distal posterior circulation territory (rostral brainstem, superior cerebellum...
The advent and wide application of new technology, especially noninvasive techniques, has enabled physicians to more completely investigate clarify the etiopathogenic mechanisms stroke. Such data have not been available until recently for Southeastern Europe. In addition, during last decades, strategies modification risk factors primary prevention may changed prevalence each subgroup stroke as well. We investigated 1, 042 consecutive patients who had first strokes, a period 5 years (from...
For Greece, information on incidence of stroke and distribution type has not been reported. We determined the first-ever in men women, by type, associated case fatality.A population-based registry was established Arcadia province, located eastern central Peloponessos, southern part Greece. Between November 1, 1993, October 31, 1995, all subjects with a were identified. ascertainment, from death certificates, hospital records, public health centers, general practitioners used.During 24-month...
A circadian variation with a morning peak on waking and arising is known to occur in both blood pressure (BP) cardiovascular event onset. second BP has been described after an afternoon sleep (siesta). This study was designed investigate the hypothesis that 2-peak diurnal of dependent physical activity occurs parallel stroke onset.The onset compared BP, pulse rate (PR), 3 independent groups Greek hypertensives 51 80 years age (633 patients, 379 subjects 24-hour ambulatory monitoring, 50...
Among 407 New England Medical Center Posterior Circulation Registry (NEMC-PCR) patients, 59% had strokes without transient ischemic attacks (TIAs), 24% TIAs before strokes, and 16% only posterior circulation TIAs. Embolism was the commonest stroke mechanism accounting for 40% of cases (24% cardiac origin, 14% arterial 2% potential sources). In 32%, large artery occlusive lesions caused hemodynamic brain infarction. Stroke mechanisms in anterior are very similar. Infarcts most often included...
We report the clinical findings and stroke mechanisms of 63 patients with cerebellar infarcts. divided intracranial vertebrobasilar circulation into proximal territory (P), fed by vertebral arteries their branches; middle (M), basilar artery its distal (D), rostral branches. Cerebellar infarcts were classified vascular territories P, M, D, P&D, middle-plus (P&M, M&D, P&M&D). Patients P (11 patients) frequently had vertigo, gait instability, limb ataxia, headache, whereas...
Data regarding stroke in young adults from Greece is scarce. We aimed to evaluate risk factors, etiology, and outcome a hospital-based prospective observational study.Data series of 253 first-ever ischemic patients aged 15-45 were collected over 10 years. Stroke etiology was classified according the Trial Org 10172 Acute Treatment criteria. Comparisons done between groups stratified by gender age. The probability death or composite vascular events during follow-up estimated Kaplan-Meier...
The transient blood pressure (BP) rise during clinical visits is usually referred to as white-coat effect (WCE). aim of the present study was investigate factors that may influence WCE.A total 2004 subjects underwent office BP measurements and 24-h ambulatory monitoring (ABPM) on same day. WCE estimated difference between average daytime (ABP). According values, population divided into normotensives (NTs), hypertensives (WCHs), masked (MHTs), sustained (SHTs). Statistical analyses were...
Previous studies on posterior cerebral artery (PCA) strokes focused mainly topography and underlying pathophysiology. However, there are no data long-term prognosis its association with the localization of infarct. All consecutive PCA registered in Athens Stroke Outcome Project between 01/1998 12/2009 were included analysis. The New England Posterior Circulation Registry criteria applied to classify them relation topography: (i) pure infarcts, including cortical-only combined cortical/deep...
Blood pressure (BP) changes are steeper in hypertensive than normotensive individuals, whereas an increased rate of BP fluctuations is associated with medial hypertrophy the carotid arteries. We evaluated association between variation derived from ambulatory blood monitoring (ABPM) data analysis and left ventricular mass (LVM).ABPM echocardiographic measurements LVM were performed 365 normotensive, 185 white-coat (WCH) 448 uncomplicated individuals.The daytime night-time systolic (SBP)...
It has been reported that hypothyroidism is associated with better survival in elderly persons. We investigated possible associations of thyroid status clinical outcome patients acute stroke.Retrospective analysis.Consecutive (median age 70 years) admitted for stroke.Total T3, T4 and TSH levels. Stroke severity evaluation using the Scandinavian Scale (SSS) Glasgow Coma Score (GCS). Handicap assessment over 12 months.Of 744 where function tests were available within first 24 h stroke, 13 had...
Data on the reproducibility of serial measurements ambulatory blood pressure in hypertensive patients are lacking. The purpose this study was to examine (1) four consecutive measurements, and (2) nocturnal falls patients.Twenty with mild moderate essential hypertension underwent separate monitorings, same day week, at 30-day intervals. Antihypertensive therapy discontinued for 2 weeks before each recording. Comparing mean values over 24h, as well diurnal, hourly periods, among recordings...
In the present case-control study we aimed to investigate association of common carotid arterial (CCA) stiffness with ischaemic stroke (IS) and determine whether this relationship was independent conventional risk factors including CCA intima-media thickness (CCA-IMT). distensibility, defined as change CCA-diameter during cardiac cycle, CCA-IMT were evaluated by means high-resolution B-mode ultrasound examination in consecutive, first-ever IS patients (n=193) age- sex-matched control...
Hierarchical clustering, a common 'unsupervised' machine-learning algorithm, is advantageous for exploring potential underlying aetiology in particularly heterogeneous diseases. We investigated embolic sources stroke of undetermined source (ESUS) using data-driven method, and explored variation recurrence between clusters.We used hierarchical k-means clustering algorithm on patients' baseline data, which assigned each individual into unique group, minimum-variance method to calculate the...
Objectives The difference between clinic and daytime ambulatory blood pressure is referred to as the white-coat effect. In this study, we investigated (i) magnitude of effect in subjects with different levels, (ii) association left ventricular mass. Methods A total 1581 underwent readings, 24-h monitoring echocardiographic assessment. Their mean systolic varied from 88.0 208.9 mmHg their diastolic 40.3 133.0 mmHg. Results negative correlation was found or (r = −0.22, P < 0.000 r −0.50,...
A circadian distribution with a single peak of stroke onset in the morning hours has been described various countries. Analysis temporal pattern symptom series 1,253 Greek first-ever patients revealed two incidence peaks between 08.00 and 10.00 h, 16.00 18.00 h. Considering different etiopathogenic types stroke, same two-peak time was evaluated all subgroups only exception lacunar which seems to predominantly occur during night sleep. secondary late afternoon not previously such detail....
To examine whether ideomotor apraxia exists in patients with subcortical ischemic lesions.A matched-control, prospective and multi-centered research design was used. Ideomotor apraxia, anxiety depression were assessed by the Movement Imitation Test Hamilton scales, respectively.Forty two consecutive stroke an equal number of healthy participants, matched age sex included. Paired-sample t-tests showed that had significantly more apractic elements their movements (t = 5.03, P < 0.01), higher...