Ling Chen

ORCID: 0000-0003-2465-8205
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About
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Research Areas
  • Immune Response and Inflammation
  • Bioactive Compounds and Antitumor Agents
  • Neonatal Respiratory Health Research
  • Research Data Management Practices
  • Antibiotic Resistance in Bacteria
  • interferon and immune responses
  • Immune Cell Function and Interaction
  • Antibiotic Use and Resistance
  • Bacterial Identification and Susceptibility Testing
  • NF-κB Signaling Pathways
  • S100 Proteins and Annexins

Tsinghua University
2025

Zhongshan Hospital of Xiamen University
2023

Hunan Agricultural University
2019

Plastic Surgery Hospital
2017

Shanxi Medical University
2016-2017

The impaired healing of Mycobacterium tuberculosis-infected wounds is a clinical challenge, and the mechanisms involved are still not clear. zebrafish model marinum infection has provided surprising insights into pathogenesis tuberculosis in humans. Similarly, major principles phases cutaneous wound conserved among adult mammals zebrafish. Here, we injected dorsal muscles observed development chronic pathology. Deep sequencing showed that gene expression related to was down-regulated,...

10.1111/wrr.12540 article EN Wound Repair and Regeneration 2017-05-01

This study was to evaluate the resistance of antimicrobial agents against pathogens from inpatients with nosocomial infection collected in Beijing, China, during 2011–2014. Measurement minimum inhibitory concentrations (MICs) carried out using broth microdilution method Clinical and Laboratory Standards Institute (CLSI) guidelines as indicator. A total 5442 Gram-negative 806 Gram-positive isolates were this Two carbapenem-resistant strains appeared among Escherichia coli (E. coli), while...

10.1080/1120009x.2016.1157946 article EN Journal of Chemotherapy 2016-06-27

Objective To study the expression and significance of toll- like receptors 4/myeloid differentiation factor 88(TLR4/MyD88)in human high invasive breast cancer cells MDA- MB - 231 poor MCF- 7. Methods TLR4, MyD88 mobility group protein B1(H MGB1) mRNA levels were detected in MB- 7 by reverse transcription- polymerase chain reaction(RT- PCR).TLR4, HMGB1 Western blotting immunofluorescence methods. Results MDA- expressed TLR4, at both levels.The TLR4 was obviously higher than...

10.3760/cma.j.issn.1001-9030.2015.05.006 article EN Zhonghua shiyan waike zazhi 2015-05-08

To study the molecular mechanism of immune regulation toll-like receptor 9/myeloid differentiation factor 88 signal pathway in neonatal acute lung injury. Fifty-one newborn mice were divided into control group (n=17), model (n=17) and experimental (n=17). The injury was established by intraperitoneal injection kanamycin. fed treated normally, while with 9 inhibitor chloroquine to inhibit pathway. Compared group, degree alleviated after administration pathological score tissue lower than but...

10.36468/pharmaceutical-sciences.1227 article EN Indian Journal of Pharmaceutical Sciences 2023-01-01
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