A5010867489- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Genomics and Rare Diseases
- RNA modifications and cancer
- Cancer, Lipids, and Metabolism
- SARS-CoV-2 and COVID-19 Research
- Extracellular vesicles in disease
- Health Systems, Economic Evaluations, Quality of Life
- Genetic factors in colorectal cancer
- COVID-19 Clinical Research Studies
- Polymer Science and PVC
- Genetic Associations and Epidemiology
- Nanoparticles: synthesis and applications
- Influenza Virus Research Studies
- CRISPR and Genetic Engineering
- RNA Research and Splicing
- Recycling and Waste Management Techniques
Universidade de São Paulo
2023-2025
Poly (vinyl chloride) (PVC) is commonly used to manufacture biomedical devices and hospital components, but it does not present antimicrobial activity enough prevent biofouling. With the emergence of new microorganisms viruses, such as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that was responsible for global pandemic caused by Disease 2019 (COVID-19), evident importance development self-disinfectant PVC environments medical clinics where infected people remain a long time....
Vaccination has played a critical role in mitigating COVID-19. Despite the availability of licensed vaccines, there remains pressing need for improved vaccine platforms that provide high protection, safety, and versatility, while also reducing costs. In response to these challenges, our aim is create self-adjuvanted against SARS-CoV-2, utilizing Virus-Like Particles (VLPs) as foundation. To achieve this, we produced bacteriophage (Qβ) VLPs prokaryotic system purified them using rapid...
Aim: Methylation of LDLR, PCSK9 and LDLRAP1 CpG sites was assessed in patients with familial hypercholesterolemia (FH). Methods: DNA methylation analyzed by pyrosequencing 131 FH 23 normolipidemic (NL) subjects. Results: LDLRP1 similar between positive (MD) negative (non-MD) for pathogenic variants FH-related genes. LDLR higher MD non-MD groups than NL subjects (p < 0.05). profiles were associated clinical manifestations cardiovascular events Conclusion: Differential is events. This profile...