- Cardiac Health and Mental Health
- Cardiovascular and exercise physiology
- Nutrition and Health in Aging
- Stroke Rehabilitation and Recovery
- Frailty in Older Adults
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Telemedicine and Telehealth Implementation
- Adipose Tissue and Metabolism
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Heart Rate Variability and Autonomic Control
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Body Composition Measurement Techniques
- Musculoskeletal pain and rehabilitation
- Health Literacy and Information Accessibility
- Hip and Femur Fractures
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Motivation and Self-Concept in Sports
- Text Readability and Simplification
- Growth Hormone and Insulin-like Growth Factors
- Cognitive Abilities and Testing
- Muscle activation and electromyography studies
- Acute Myocardial Infarction Research
VA Boston Healthcare System
2011-2021
VA Pittsburgh Healthcare System
2015-2021
University of Pittsburgh
2020
University of Pittsburgh Medical Center
2017-2020
National Center for PTSD
2016-2017
Indiana University School of Medicine
2017
Boston University
2017
Richard L. Roudebush VA Medical Center
2017
Indiana University – Purdue University Indianapolis
2017
Regenstrief Institute
2017
Exercise-induced increase in peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) expression has been shown to the of fibronectin type III domain containing 5 (FNDC5) gene and thereby its product, irisin, mice. Given that exercise intolerance is a hallmark characteristic heart failure (HF), because PGC-1α irisin promote benefits animals, we hypothesized these genes relates aerobic performance patients with HF.Systolic HF (left ventricular ejection fraction ≤40%) underwent...
Most eligible patients do not participate in traditional clinic-based cardiac rehabilitation (CR) despite well-established benefits. Novel approaches to overcome logistic obstacles and increase efficiencies of learning, behavior modification, exercise surveillance may CR participation. In an observational study, the feasibility utility a mobile smartphone application for CR, Heart Coach (HC), were assessed as part standard care. Ultimately, innovative models incorporating HC facilitate...
Abstract Aging is associated with performance reductions in executive function and episodic memory, although there substantial individual variability cognition among older adults. One factor that may be positively aging physical activity. To date, few studies have objectively assessed activity young adults, examined whether differentially aging. Young ( n =29, age 18–31 years) adults =31, ages 55–82 completed standardized neuropsychological testing to assess memory capacities. An...
Purpose: Frailty is highly prevalent among older adults with cardiovascular disease (CVD) and associated greater than 2-fold risk for morbidity mortality, independent of age comorbidities. Many candidates are not referred to cardiac rehabilitation (CR) under the assumption that they too frail benefit. We hypothesized CR similar benefits as intermediate-frail nonfrail adults. Methods: Retrospective analysis CVD patients who completed a phase II program. Patients classified by meeting ≥2...
Exercise is critical for health maintenance in late life. The COVID-19 shelter place and social distancing orders resulted wide-scale interruptions of exercise therapies, placing older adults at risk the consequences decreased mobilization. purpose this paper to describe rapid transition Gerofit facility-based group program telehealth delivery. This Gerofit-to-Home (GTH) continued with group-based synchronous classes that ranged from 1 24 Veterans per class 9 offered week different...
Background Cardiac rehabilitation is an established performance measure for adults with ischemic heart disease, but patient participation remarkably low. Home‐based cardiac (HBCR) may be more practical and feasible, evidence regarding its efficacy limited. We sought to compare the effects of HBCR versus facility‐based (FBCR) on functional status in patients disease. Methods Results This was a pragmatic trial 237 selected recent disease event, who enrolled or FBCR between August 2015...
BACKGROUND: Cardiac rehabilitation (CR) programs reduce morbidity and mortality in patients with ischemic heart disease but are vastly underutilized the United States, including Veterans Health Administration (VA) Healthcare System. Numerous barriers affecting utilization have been identified other health care systems, specific factors unknown. We sought to identify facilitators associated of CR VA facilities. METHODS: performed a qualitative study 56 patients, providers, program managers at...
This pilot study assessed the effects of cardiopulmonary exercise testing and cardiorespiratory fitness on plasma neuropeptide Y (NPY), allopregnanolone pregnanolone (ALLO), cortisol, dehydroepiandrosterone (DHEA), their association with pain sensitivity. Medication-free trauma-exposed participants were either healthy (n = 7) or experiencing comorbid chronic pain/posttraumatic stress disorder (PTSD) 5). Peak oxygen consumption (VO2) during was used to characterize fitness. VO2 correlated...
This study used VA inpatient files to determine the proportion of eligible veterans with ischemic heart disease who participated in cardiac rehabilitation (CR), whether presence an on-site CR program is associated greater participation, and characteristics participants.
Introduction: Despite strong incentives to use cardiac rehabilitation (CR), patient participation is low in the Veterans Health Administration (VHA). This paradoxical given that VHA an integrated health care system offers a range of CR programs which should logically reduce barriers access participation. The purpose this study was better understand contextual factors influence and how patients consider together when making decisions about Materials Methods: Using qualitative design we...
Exercise intolerance is common among adults with heart failure (HF) and a strong prognostic indicator. We examined maximal inspiratory pressure (MIP) as an indicator of submaximal exercise capacity in older HF patients.
Background and Purpose: Participation in regular exercise is low among young adults contributing to a rapid increase obesity chronic health conditions. Enhancing motivation key element initiation maintenance. The current investigation considers factors relevant the transtheoretical model (TTM), self-determination theory (SDT), self-efficacy (SE), body image anxiety (BIA) relation college students’ exercise. Design Main Outcome Measures: In this cross sectional study, lower division students...
While cardiopulmonary exercise testing (CPX) assessment is generally regarded as an optimal means to assess functional capacity in heart failure (HF) patients, strength parameters are omitted. CPX indices collected recovery may provide additional insight regarding function, including strength. We performed a cross-sectional controlled study. Systolic HF patients (aged ≥50 years) and age-matched controls were assessed using evaluations. Standard during (peak oxygen consumption [VO2], first...
Objective. While multimodal treatment approaches for fibromyalgia (FM), incorporating exercise, have been found most effective, information about factors associated with exercise adoption and maintenance is lacking. Design, Setting, Methods. Women veterans FM (N = 19) completed an anonymous Internet survey measuring impact (FI), of behavior, self-efficacy exercise. Using classifications behavior specified by the transtheoretical model, participants classified in action or (AM) stages was...
Purpose: Current American Association of Cardiovascular and Pulmonary Rehabilitation guidelines rely primarily on cardiovascular disease (CVD)-centered metrics to stratify risk guide care. Yet, contemporary CVD patients are often older more likely have risks attributable rudimentary functional impairments that can disproportionate bearing management prognosis. In this study, we stratified using novel indices physical function as well traditional in enrolling phase II cardiac rehabilitation...
Purpose: Most older adults eligible for cardiac rehabilitation (CR) do not participate or with low frequency, although it is a standard of care patients cardiovascular disease (CVD). Identifying the barriers to adult participation key in improving CR efficacy. Methods: A range patient characteristics was analyzed relation on-site frequency program by patients. These included demographics and indications referral, as well CVD non-CVD diagnoses. The prevalence these compared among three...