- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Diabetes Treatment and Management
- Gastroesophageal reflux and treatments
- Fatty Acid Research and Health
- Body Contouring and Surgery
- Gastric Cancer Management and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Gut microbiota and health
- Cardiovascular Function and Risk Factors
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Adipose Tissue and Metabolism
- Renal Transplantation Outcomes and Treatments
- Metabolomics and Mass Spectrometry Studies
- Regulation of Appetite and Obesity
- Cancer Genomics and Diagnostics
- Adrenal and Paraganglionic Tumors
- Childhood Cancer Survivors' Quality of Life
- Cardiovascular Disease and Adiposity
- Cardiac, Anesthesia and Surgical Outcomes
- Abdominal vascular conditions and treatments
- Nutritional Studies and Diet
- Abdominal Trauma and Injuries
- Metabolism, Diabetes, and Cancer
Gdańsk Medical University
2014-2023
Pomeranian Medical University
2013
American Gastroenterological Association
2004
While small amounts of odd-chain fatty acids (OCFAs) and branched-chain (BCFAs) were known to be present in mammals, it was quite recently that they shown play an important role human health. However, still little is on OCFA BCFA profiles subjects who have obesity. The aim this study verify whether obesity associated with changes serum profiles.Serum content determined by gas chromatography-mass spectroscopy 23 patients excess weight 21 nonobese controls.Six OCFAs six BCFAs (three iso-BCFAs...
Subjects with morbid obesity have low levels of serum branched-chain fatty acids (BCFAs), which correlate inversely insulin resistance, hypertriglyceridemia, and inflammation. Recent evidence suggests BCFAs are produced during amino acid (BCAA) catabolism in human adipose tissue. Elevated concentrations BCAAs associated resistance.In this single-center study, we evaluated the effect one anastomosis gastric bypass (OAGB) on circulating BCFA BCAA. Moreover, determined expression genes involved...
The Metabolic and Bariatric Surgery Chapter of the Association Polish Surgeons (Polish acronym: SCMiB TCHP) is a specialist scientific society representing bariatric surgeons as well specialists from other disciplines professions cooperating with them during provision services in field metabolic surgery, entire care process before after surgery. following standards constitute minimum requirements set by TCHP for good practice basic throughout its period, which ensure satisfactory safety...
Fatty acids containing a cyclopropane ring in their structure (cyclopropane FA) have been found wide variety of bacteria, number protozoa, and Myriapoda. Little is known about FA mammal, especially human tissues. The present study deals with the identification adipose tissue serum humans rats. extracted from obtained obese women during bariatric surgery were methylated analyzed on GC-MS. We identified: cyclopropaneoctanoic acid 2-hexyl, 2-octyl, cyclopropanenonanoic acid,...
The Roux-en-Y gastric bypass (RYGB) is an effective treatment of morbid obesity leading to type 2 diabetes mellitus (T2DM) resolution. However, evidence demonstrates that standard limb lengths can have a limited impact on long-term weight loss and durable T2DM remission.The authors evaluated the biliary (BL) length laboratory markers in 2-year follow-up.The data 93 obese patients with who underwent RYGB between 2008 2010 were collected from prospectively designed database. BL was one group...
Bariatric surgery contributes to the improvement in glucose metabolism that may be related a postoperative increase serum bile acids (BAs). Three commonly used types of bariatric procedures, laparoscopic sleeve gastrectomy (LSG) (without creation loop), Roux-en-Y gastric bypass (RYGB), and omega-loop (OLGB) (with shorter 100–150 cm longer 200–280 loops, respectively), differ their effects on glycemic control. The aim study was compare various procedures BA concentration homeostasis. Serum...
Background/Aims: The fatty acid profile in plasma lipids contributes to the increase of high sensitivity C-reactive protein (hsCRP), a marker inflammation and predictor cardiovascular risk. aim this study was examine relationship between specific acids (FA) serum hsCRP morbidly obese woman. Methods: included 16 (mean BMI= 43 ± 2.2 kg/m2) non-diabetic woman awaiting bariatric surgery. FA extracted from were methylated analyzed on GC-MS. Commercially available ELISA kits used determine...
Routine laboratory lipid assays include simple measurements of total cholesterol, triacylglycerols and HDL. However, lipids are a large group compounds involved in many metabolic pathways, their alterations may have serious health consequences. In this study, we used
Abstract We recently reported the presence of various cyclopropane fatty acids—among them, cyclopropaneoctanoic acid 2‐hexyl—in adipose tissue obese women. The aim this study was to verify whether 2‐hexyl in human serum associated with obesity or chronic kidney disease (both being related dyslipidemia), and find potential associations between level compound specific markers these conditions. concentration determined by gas chromatography–mass spectrometry (GC–MS) non‐obese controls,...
Abstract Background The number of morbidly obese kidney transplant candidates is growing. They have limited access to transplantation and are at a higher risk postoperative complications. Bariatric surgery considered as safe weight loss method in those patients. Objectives Matched pair analysis was designed analyze the preparatory after bariatric procedures end-stage disease (ESKD) non-ESKD Methods Twenty patients with ESKD underwent our Centre Excellence for Metabolic Surgery between 2015...
Emerging evidence suggests that microbiota plays a crucial role in the development, progression, and therapeutic options obesity its comorbidities. This study assessed preoperative probiotic therapy’s impact on bariatric treatment outcomes. A 12-week randomized, double-blind, placebo-controlled trial with 48 patients undergoing surgery was conducted. Participants received probiotics—Sanprobi Barrier—which contained nine strains of bacteria: Bifidobacterium bifidum W23, lactis W51 W52,...
Background/Aims: Cytosolic glycerol 3-phosphate dehydrogenase (cGPDH) is a key enzyme providing for triacylglycerol synthesis in adipose tissue and regarded as marker adipocyte differentiation. The aim of this study was to test the hypothesis that an increase cGPDH gene expression subcutaneous associated with obesity. Methods: mRNA levels human were analysed by Real-Time PCR. Results: We found activity level greater obese patients than lean subjects positively correlated BMI fat mass....
Introduction: The potentially differential roles of both forms ghrelin in obesity are undefined, and little is known about desacyl ghrelin's (DAG) regulation by meals. We aimed to assess changes acyl (AG) DAG response mixed-meal consumption obese non-obese subjects. Material methods: Venous blood for plasma glucose, AG assays were collected groups after an overnight fast two hours the a standard 300 kcal-mixed meal (Nutridrink, Nutricia). Results: Mean fasting values significantly lower...
The aim of this study was to re‐evaluate possible associations between BMI and (1) stearoyl‐CoA desaturase‐1 ( SCD1 ) gene expression in adipose tissue; (2) tissue or serum lipids oleic acid/stearic acid (18:1/18:0) desaturation index (DI); (3) less studied SCD isoform SCD5 obese patients. mRNA levels from 16 morbidly women were analyzed by RT‐PCR. Fatty composition whole determined with gas chromatography‐mass spectrometry. levels, as well 18:1/18:0 DI tissue, correlated positively A weak...
To compare the effect of RYGB and OAGB on patients after failed treatment obesity by laparoscopic sleeve gastrectomy (LSG). A case–control study based a prospectively maintained database reoperated LSG, which included 33 who underwent conversion 47 conversion. The mean %EBWL 5-year follow-up for RYGBc vs OAGBc was 84.04% 72.95% (p = 0.2176), respectively. Complete long-term diabetes remission observed significantly more frequently in than group (97.3% 33%; p 0.035). There were no other...