Xiaona Xu

ORCID: 0000-0003-2500-2689
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Research Areas
  • MicroRNA in disease regulation
  • Aquaculture disease management and microbiota
  • Cancer, Hypoxia, and Metabolism
  • Circular RNAs in diseases
  • RNA modifications and cancer
  • Physiological and biochemical adaptations
  • Cancer-related molecular mechanisms research
  • Pericarditis and Cardiac Tamponade
  • Cardiac Arrhythmias and Treatments
  • Cancer-related gene regulation
  • High Altitude and Hypoxia
  • Aquaculture Nutrition and Growth
  • Atrial Fibrillation Management and Outcomes
  • Ultrasound and Hyperthermia Applications
  • Bone Metabolism and Diseases
  • Cardiac pacing and defibrillation studies
  • Aquatic life and conservation
  • RNA regulation and disease
  • Metallurgy and Material Forming
  • Glioma Diagnosis and Treatment
  • HVDC Systems and Fault Protection
  • Kruppel-like factors research
  • Extracellular vesicles in disease
  • Heme Oxygenase-1 and Carbon Monoxide
  • Nanocluster Synthesis and Applications

Xi'an Jiaotong University
2013-2024

Anhui Academy of Agricultural Sciences
2022-2024

Huazhong Agricultural University
2024

Shanghai Ocean University
2019-2023

Ministry of Agriculture and Rural Affairs
2023

Tianjin Medical University
2017-2023

Second Hospital of Tianjin Medical University
2017-2023

Guilin Medical University
2023

China Fishery Machinery and Instrument Research Institute
2022

Harbin Medical University
2019-2021

Abstract BACKGROUND Adelphocoris suturalis is a destructive pest that attacks > 270 plants, including cotton, maize, soybean, and fruit trees. can cause tremendous crop losses when the density exceeds economic thresholds, but because it be both phytophagous zoophytophagous serve as natural enemy of other pests below threshold. Effective control its population beneficial for maximizing yield profits. RNA interference (RNAi) has potential to viable alternative conventional pesticide‐based...

10.1002/ps.8077 article EN Pest Management Science 2024-03-12

The current study aims to elucidate the role of miRNA-338-3p (miR-338-3p) in invasion renal cell carcinoma (RCC).Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was performed detect expression miR-338-3p human RCC lines with high metastatic potential (Caki-1) and low (786-O), respectively. Caki-1 786-O cells were transfected mimic or inhibitor. Wound healing assay, Transwell assay western blotting analyze invasive ability activin receptor-like kinase 5 (ALK5) lines....

10.18632/oncotarget.19329 article EN Oncotarget 2017-07-18

Summary Tyrp1 gene, as a member of the tyrosinase family, has undergone recent duplication event during fourth‐round whole genome in common carp. In this research, three genes were identified Oujiang‐color carp ( Cyprinus carpio var. color ). The similar expression patterns and close phylogenetic relationship indicated that Tyrp1c is homologous to Tyrp1b possibly originated from ancient . rates synonymous non‐synonymous substitution K / s ) across teleost phylogeny Tyrp1a more likely be...

10.1111/age.13071 article EN Animal Genetics 2021-05-03

Papillary thyroid carcinoma (PTC) is a common endocrine tumor. This study found that different iodine concentrations affected the proliferation, apoptosis, and migration of PTC. For this study, we collected clinical information from PTC patients monitored levels urinary iodine, LC3-II, caspase-3 in cancer tissue, BRAF kinase peripheral blood patients. We also apoptosis ability human papillary-thyroid (BCPAP) cells at their association with changes autophagy activity BCPAP high (10-3 mol/l)....

10.1016/j.biopha.2019.109476 article EN Biomedicine & Pharmacotherapy 2019-09-26

This study introduces a modified DF2016 criterion to model ductile fracture of sheet metals from shear equibiaxial tension. The is so that material constant equal the strain at tension, which can be easily measured by bulging experiments. To evaluate performance criterion, experiments are conducted for QP980 with five different specimens stress states plasticity steel characterized Swift–Voce hardening law and pDrucker function, calibrated inverse engineering approach. A XTOP digital image...

10.3390/ma17040958 article EN Materials 2024-02-19

Folic acid (FA) is an essential vitamin for the growth and health of aquatic organisms in aquaculture industry. The purpose this study was to investigate effects potential mechanisms action dietary FA on immune response red swamp crayfish (Procambius clarkii). Crayfish (n = 360; 3 tanks 20 each treatment) were fed diets containing different levels (0 [control], 0.5, 1, 2, 4, 8 mg/kg dry feed weight) 60 d. Broken-line analysis based final weight specific rate revealed that optimal level...

10.1016/j.aqrep.2024.102077 article EN cc-by-nc-nd Aquaculture Reports 2024-04-15

Recent studies have shown that N6-methyladenosine (m6A) methylation, one of the most prevalent epigenetic modifications, is involved in diabetes mellitus. However, whether m6A regulates diabetic vascular endothelium injury still elusive. Present research aimed to investigate regulation and mechanism on injury. Upregulation METTL3 was observed high glucose (HG)-induced human umbilical vein endothelial cells (HUVECs), following with upregulation methylation level. Functionally, silencing...

10.1016/j.heliyon.2023.e13721 article EN cc-by-nc-nd Heliyon 2023-02-14

Sporadic colorectal cancer (sCRC) is one of the most commonly diagnosed cancers worldwide, but few genetic markers have been identified and used for its early detection. MicroRNAs are diverse cellular regulators in pathogenesis that bind to 3′-untranslated region (3′-UTR) their target mRNAs, variants within miRNA sites on sCRC-related genes may influence pathogenesis. To investigate this possibility, we a bioinformatical method screen SNPs putative changes recognition 3′-UTR genes. The...

10.1080/15384047.2017.1323584 article EN Cancer Biology & Therapy 2017-05-11

Vascular calcification is an independent risk factor for plaque instability and associated with endothelial cell function. Here, we investigated the role of function in atherosclerotic plaques. We hypothesized that atherosclerosis would be dysfunction bosentan (Tracleer®), a dual endothelin-receptor antagonist, preserve apolipoprotein E-deficient (ApoE −/− ) mouse model atherosclerosis. Accordingly, 4–6-week-old ApoE mice were fed high-fat diet treated bosentan, effects this treatment on...

10.1155/2019/8348430 article EN cc-by BioMed Research International 2019-12-05

Atrial remodeling takes part in the pathogenesis of atrial fibrillation (AF). Aliskiren, as a direct renin inhibitor, has been shown to exert protective effects against arrhythmia. The aim this study was investigate potential role aliskiren chronic intermittent hypoxia (CIH) rat model.A total 45 Sprague-Dawley rats were randomly assigned into three groups (n=15 per group): control group; CIH and with (CIH-A) group. CIH-A subjected for 6 h day 4 weeks. fibrosis evaluated using Masson's...

10.2147/dddt.s262922 article EN cc-by-nc Drug Design Development and Therapy 2020-09-01

<title>Abstract</title> Recent studies have shown that N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) methylation, one of the most prevalent epigenetic modifications, is involved in diabetes mellitus. However, whether m<sup>6</sup>A plays roles diabetic vascular endothelium injury still elusive. Present research aimed to investigate regulation and mechanism on injury. Upregulation METTL3 was observed high glucose (HG)-induced human umbilical vein endothelial cells (HUVECs), followed by...

10.21203/rs.3.rs-1981358/v1 preprint EN cc-by Research Square (Research Square) 2022-08-23

Objective To investigate the MRI features of adult pilocytic astrocytoma in fourth ventricle and to improve diagnostic accuracy. Methods The clinical data manifestations 6 cases confirmed by pathology were retrospectively analyzed. Results Two solid mass four cystic mass. All company with obstructive hydrocephalus, two presented hemorrhage, none them had peritumoral edema. The part tumors showed hypointensity on T1WI DWI, hyperintensity T2WI. long T1 T2 signal, FLAIR. remarkably...

10.3760/cma.j.issn.1674-4756.2017.11.028 article EN Central Plains Medical Journal 2017-06-10

A 66-year-old woman was admitted to our hospital due chest distress and shortness of breath during 1 week. Transthoracic echocardiography (TTE) revealed massive pericardial effusion multiple, irregular high-density echo "tumor-like" masses on the heart, with largest one apex. However, there were no found by computed tomography (CT) scan, except for increased lipids around coronary artery. We performed emergency pericardiocentesis drainage relieve symptoms. The positron emission tomography/CT...

10.1002/jcu.23348 article EN Journal of Clinical Ultrasound 2022-09-29
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