A5100332999- Parasitic Infections and Diagnostics
- Circular RNAs in diseases
- Insect Resistance and Genetics
- MicroRNA in disease regulation
- Insect symbiosis and bacterial influences
- Insect and Pesticide Research
- Cancer-related molecular mechanisms research
- Plant-Microbe Interactions and Immunity
- Viral Infectious Diseases and Gene Expression in Insects
- Invertebrate Immune Response Mechanisms
- Virus-based gene therapy research
- Plant Pathogens and Fungal Diseases
- Insect-Plant Interactions and Control
- Nematode management and characterization studies
- Plant Disease Resistance and Genetics
- Plant and Fungal Interactions Research
- Plant Molecular Biology Research
- Toxoplasma gondii Research Studies
- Immune Cell Function and Interaction
- Plant Stress Responses and Tolerance
- CRISPR and Genetic Engineering
- Plant Virus Research Studies
- RNA Research and Splicing
- RNA modifications and cancer
- Aquaculture disease management and microbiota
Southwest University
2016-2025
Shanghai University of Traditional Chinese Medicine
2022-2025
State Administration of Traditional Chinese Medicine of the People's Republic of China
2022-2025
Chinese Academy of Agricultural Sciences
2019-2025
Zhejiang University of Science and Technology
2024-2025
Southwest Jiaotong University
2025
Southwest Forestry University
2024
Ministry of Agriculture and Rural Affairs
2021-2024
Shandong Agricultural University
2014-2024
Jinhua Central Hospital
2024
Arbuscular mycorrhizal fungi (AMF) are considered as a potential biotechnological tool for improving phytostabilization efficiency and plant tolerance to heavy metal-contaminated soils. However, the mechanisms through which AMF help alleviate metal toxicity in plants still poorly understood. A greenhouse experiment was conducted evaluate effects of two species (Funneliformis mosseae Rhizophagus intraradices) on growth, Pb accumulation, photosynthesis antioxidant enzyme activities leguminous...
Abstract Circular RNAs (circRNAs) were shown to play an important role in the occurrence and progression of tumors. However, functions nuclear genome-derived circRNAs localized mitochondria tumor cells remain largely elusive. Here, we report that circPUM1, a circular RNA derived from back-splicing pre-mRNAs genome PUM1, localizes mitochondria. The expression level circPUM1 is positively correlated with HIF1α accumulation under CoCl 2 -induced intracellular hypoxic-like condition esophageal...
Microsporidia, which are obligate intracellular pathogenic organisms, cause huge economic losses in agriculture and even threaten human health. The key to successful infection by the microsporidia is their unique invasion apparatus includes polar filament, polaroplast, posterior vacuole. When mature spore activated geminate, filament uncoils undergoes a rapid transition into hollow tube that transports sporoplasm components including microsporidian nucleus host cells. Details of structural...
The effect of an intestinal microflora consisting selected microbial species on myoelectric activity small intestine was studied using germ-free rat models, with recording before and after specific colonization, in the unanesthetized state. Intestinal transit, neuropeptides blood (RIA), neuromessengers wall were determined. Clostridium tabificum vp 04 promoted regular spike burst activity, shown by a reduction migrating complex (MMC) period from 30.5 ± 3.9 min state to 21.2 0.14 ( P <...
ABSTRACT Seed treatment with Trichoderma harzianum strain T22, which results in colonization of plant roots but little or no shoots leaves, had substantial effects on growth and disease expression maize inbred line Mo17. Shoots 10-day-old seedlings grown a sandy loam field soil were larger (roots nearly twice as long) the presence T22 than its absence. Both main secondary increased size area root hair was greater T22. However, per unit length control plants. Increased probably due to direct...
Abstract Background Artificial selection played an important role in the origin of modern Glycine max cultivars from wild soybean soja . To elucidate consequences artificial accompanying domestication and improvement soybean, 25 new 30 published whole-genome re-sequencing accessions, which represent wild, domesticated landrace, Chinese elite populations were analyzed. Results A total 5,102,244 single nucleotide polymorphisms (SNPs) 707,969 insertion/deletions identified. Among SNPs detected,...
The tuberculous granuloma is an elaborately organized structure and one of the main histological hallmarks tuberculosis. Macrophages, which are important immunologic effector antigen-presenting cells, cell type found in have high plasticity. Macrophage polarization during bacterial infection has been elucidated numerous recent studies; however, macrophage formation development rarely reported. It remains to be clarified whether differences activation status macrophages affect formation. In...
Background Trehalase, an enzyme that hydrolyzes trehalose to yield two glucose molecules, plays a pivotal role in various physiological processes. In recent years, trehalase proteins have been purified from several insect species and are divided into soluble (Tre-1) membrane-bound (Tre-2) trehalases. However, no functions of the trehalases chitin biosynthesis insects yet reported. Principal Findings The Spodoptera exigua (SeTre-2) was characterized our laboratory previously. this study, we...
Due to its efficient broad-spectrum antimicrobial activity, Trichoderma has been established as an internationally recognized biocontrol fungus. In this study, we found and identified a novel strain of asperellum, named GDFS1009. The mycelium T. asperellum GDFS1009 exhibits high growth rate, sporulation capacity, strong inhibitory effects against pathogens that cause cucumber fusarium wilt corn stalk rot. secretes chitinase, glucanase, protease, which can degrade the cell walls fungi...
Single-atom catalysis is mainly focused on its dispersed high-density catalytic sites, but delicate designs to realize a unique mechanism in terms of target reactions have been much less investigated. Herein an iron single atomic site catalyst anchored 2-D N-doping graphene (Fe-SASC/G) was synthesized and further employed as biomimetic sensor electrochemically detect hydrogen peroxide, showing extremely high sensitivity 3214.28 μA mM–1 cm–2, which higher than that (6.5 cm–2) 1-D carbon...
Abstract Recently, peptide-based drugs have gained unprecedented interest in discovering and developing antifungal due to their high efficacy, broad-spectrum activity, low toxicity few side effects. However, it is time-consuming expensive identify peptides (AFPs) experimentally. Therefore, computational methods for accurately predicting AFPs are highly required. In this work, we develop AFP-MFL, a novel deep learning model that predicts only relying on peptide sequences without using any...
Abstract We aimed to assess the epidemiological characteristics of respiratory syncytial virus (RSV) infection in Chinese children at different phases coronavirus disease 2019 (COVID‐19) pandemic, that is, before, during pandemic and after easing restrictive measures. included 123 623 patients aged 0–18 years with symptoms who were suspected RSV from January 1, June 30, 2023 Hangzhou Children's Hospital. Clinical information test result extracted laboratory system. calculated positive rate...
Abstract Background Human health is seriously threatened by antibiotic-induced intestinal disorders. Herein, we aimed to determine the effects of Autoinducer-2 (AI-2) combined with Lactobacillus rhamnosus GG ( LGG ) on barrier function dysbiosis neonatal mice. Methods An mouse model was created using antibiotic cocktails, and mice were randomized into control, AI-2, , + AI-2 groups. Intestinal short-chain fatty acids concentrations detected mass spectrometry chemiluminescence, respectively....
Protegrin antimicrobial peptides possess activity against gram-positive and gram-negative bacteria yeasts. An extensive structure–activity relationship (SAR) study was conducted on several hundred protegrin analogues to gain understanding of the between primary secondary structure protegrins their activities, identify a analogue for clinical development. Native sequence are cationic, amphiphilic that characterized by presence β-sheet is maintained two disulfide bridges. The key stability...
A recessive Arabidopsis mutation, carbohydrate accumulation mutant1 (cam1), which maps to position 22.8 on chromosome 3, was identified by screening leaves of ethyl methanesulfonate-mutagenized M2 plants stained with iodine for altered starch content. Increased content in the cam1 mutant observed at onset flowering. This also had a delayed floral initiation phenotype more rosette than parental line. In addition, activities several enzymes associated metabolism were mutant. The late-flowering...
Microsporidia have attracted much attention because they infect a variety of species ranging from protists to mammals, including immunocompromised patients with AIDS or cancer. Aside the study on Nosema ceranae, few works focused elucidating mechanism in host response microsporidia infection. bombycis is pathogen silkworm pébrine that causes great economic losses industry. Detailed understanding (Bombyx mori) infection by N. helpful for prevention this disease. A genome-wide survey gene...