A5004636424- Silk-based biomaterials and applications
- Invertebrate Immune Response Mechanisms
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Insect Resistance and Genetics
- Neurobiology and Insect Physiology Research
- Silkworms and Sericulture Research
- Parasitic Infections and Diagnostics
- Aquaculture Nutrition and Growth
Southwest University
2013-2020
State Key Laboratory of Silkworm Genomic Biology
2013
Microsporidia have attracted much attention because they infect a variety of species ranging from protists to mammals, including immunocompromised patients with AIDS or cancer. Aside the study on Nosema ceranae, few works focused elucidating mechanism in host response microsporidia infection. bombycis is pathogen silkworm pébrine that causes great economic losses industry. Detailed understanding (Bombyx mori) infection by N. helpful for prevention this disease. A genome-wide survey gene...
Vitellogenin receptors (VgRs) play crucial roles in oogenesis by mediating endocytosis of vitellogenin and other nutrients ovipara. We conducted small RNA sequencing screening with a luciferase reporter system, found that bmo-miR-2739 novel miRNA (novel-miR-167) coordinately regulate the expression VgR Bombyx mori (BmVgR). Further analyses suggested these two miRNAs direct target repression binding directly to BmVgR 3' untranslated region. Forced either using piggyBac system blocked (Vg)...
Vitellogenin receptors (VgRs) play critical roles in egg formation by transporting vitellogenin (Vg) into oocytes insects. Although the function of VgR insects is well studied, transcriptional regulation this gene still unclear. Here, we cloned promoter from Bombyx mori (BmVgR), and predicted many POU cis-response elements (CREs) its promoter. Electrophoretic mobility shift chromatin immunoprecipitation assays showed that transcription factor POU-M2 bound directly to CREs Overexpression an...