A5003534135- Analytical Chemistry and Chromatography
- Antimicrobial Peptides and Activities
- Microfluidic and Capillary Electrophoresis Applications
- Metabolomics and Mass Spectrometry Studies
- Biochemical and Structural Characterization
- Pesticide Residue Analysis and Safety
- Oral microbiology and periodontitis research
- Mass Spectrometry Techniques and Applications
- Psidium guajava Extracts and Applications
- Bacterial biofilms and quorum sensing
- Peroxisome Proliferator-Activated Receptors
- Analytical chemistry methods development
- Innovative Microfluidic and Catalytic Techniques Innovation
- Chromatography in Natural Products
- Cancer, Hypoxia, and Metabolism
- Traditional Chinese Medicine Analysis
- Neonatal Respiratory Health Research
- Essential Oils and Antimicrobial Activity
- Carbon and Quantum Dots Applications
- Adipose Tissue and Metabolism
- Eicosanoids and Hypertension Pharmacology
- Soil Carbon and Nitrogen Dynamics
- Nanocluster Synthesis and Applications
- Ginger and Zingiberaceae research
- Cardiac Fibrosis and Remodeling
Hainan University
2015-2025
Capital Medical University
2017-2025
Beijing Chao-Yang Hospital
2025
Beijing Anzhen Hospital
2022-2025
Huazhong Agricultural University
2023-2024
Ministry of Education of the People's Republic of China
2019-2022
Fuzhou University
2022
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2021
Shandong First Medical University
2021
Shandong Provincial QianFoShan Hospital
2020
ABSTRACT Biochar amendment is one of the most promising agricultural approaches to tackle climate change by enhancing soil carbon (C) sequestration. Microbial‐mediated decomposition processes are fundamental for fate and persistence sequestered C in soil, but underlying mechanisms uncertain. Here, we synthesise 923 observations regarding effects biochar addition (over periods ranging from several weeks years) on C‐degrading enzyme activities 130 articles across five continents worldwide. Our...
Abstract The process of vascular remodeling is associated with increased hypoxia. However, the contribution hypoxia-inducible factor 1α (HIF1α), key transcription mediating cellular hypoxic responses, to established, but not completely understood. In angiotensin II (Ang II)-induced model, HIF1α was and activated in smooth muscle cells (VSMCs). Selective genetic disruption Hif1a VSMCs markedly ameliorated Ang II-induced remodeling, as revealed by decreased blood pressure, aortic thickness,...
Dickkopf-related protein 3 (DKK3) is a secreted that involved in the regulation of cardiac remodeling and vascular smooth muscle cell differentiation, but little known about its role atherosclerosis.We tested hypothesis DKK3 atheroprotective using both epidemiological experimental approaches. Blood levels were measured Bruneck Study 2000 (n=684) then 2005 (n=574). DKK3-deficient mice crossed with apolipoprotein E-/- to evaluate atherosclerosis development vessel injury-induced neointimal...
Temporin-GHc (GHc) and temporin-GHd (GHd) produced by the frog Hylarana guentheri had shown broad-spectrum antibacterial activities against bacteria fungi. In this study, we investigated whether they exert antibiofilm cariogenic bacteria, Streptococcus mutans. GHc GHd adopt random coil conformation in aqueous solution convert to α-helix membrane mimetic environments using circular dichroism spectroscope. They are positively charged histidine, with polar nonpolar amino acids on opposing faces...
A gradient elution system for pressure-driven liquid chromatography (LC) on a chip was developed carrying out faster and more efficient chemical analyses. Through computational fluid dynamics simulations an experimental study, we found that the use of cross-Tesla structure with 3 mm mixing length effective two liquids. using mixer fabricated 20 × silicon separation channel pillar array columns sample injection channel. mixed solution water fluorescein in methanol delivered to 7 s after...
In our previous study, temporin-GHaR (GHaR) showed potent antimicrobial activity with strong hemolytic toxicity. To overcome its weakness, we designed GHaR6R, GHaR7R, GHaR8R, GHaR9R, and GHaR9W by changing the number of positive charges hydrophobic surface GHaR. With exception toxicity derived peptides had been reduced, activities remained close to parent peptide (except for GHaR9R). exhibited a great bactericidal effect on Streptococcus mutans (S. mutans), which is one main pathogens...
Objective: Neutrophil infiltration plays an important role in the initiation and development of abdominal aortic aneurysm (AAA). Recent studies suggested that neutrophils could release neutrophil extracellular traps (NETs), leading to tissue injury cardiovascular diseases. However, NETs AAA is elusive. This study aimed investigate underlying mechanism development. Methods Results: An angiotensin II (Ang II) infusion-induced model was established during Immunofluorescence staining showed...
The ectopic thyroid gland is an abnormal development of the embryo. Most occurs in path around thyroglossal duct or on lateral side neck. However, heart, which rare. We report a case right ventricular thyroid. This highlights imaging characteristics computed tomography (CT) and cardiac magnetic resonance (CMR) discusses underlying mechanisms for timely diagnosis.
The abuse of antibiotics has led to the emergence multidrug-resistant bacteria, which is becoming a serious worldwide problem people have face. In our previous study, temporin-GHa (GHa) cloned from Hylarana guentheri showed antimicrobial activity against Gram-positive bacteria. order improve its therapeutic potential, we used template-based and database-assisted design obtain three derived peptides by replacing histidine at both ends GHa with lysine, exhibited faster stronger bactericidal...
Abstract Monitoring abnormal changes in hydrogen peroxide (H 2 O ) levels mammalian cells is essential to understanding its physicochemical functions biological systems. Generally, H fluorescent probes used for intracellular monitoring are limited the long response time and low sensitivity. Herein, 1,8‐naphthimide‐based probe (NPB) with excellent photostability was confirmed be an specific due oxidation of borate ester phenol. Compared previously reported molecular probes, NPB displayed...
In this paper, the volatile compounds of Schisandra chinensis obtained by different extraction techniques including supercritical fluid (SFE), steam distillation (SD), Soxhlet (SE) and ultrasound-assisted (UAE) were investigated for first time. The sample preparation procedure GC-MS analysis was optimized then 37, 45, 27 37 identified in samples SFE, SD, SE UAE methods, respectively. As therapeutic effect traditional Chinese medicine is usually based on multifarious essential components or...