Multi-system inflammatory syndrome in children (MIS-C) associated with COVID-19 is a recently recognised potentially life-threatening entity. There limited data on post-MIS-C sequelae. 21 fulfilling the WHO criteria for MIS-C were included our study. Data collected at baseline and 12–16 weeks post-discharge to look any persistent sequelae mainly relating lungs or heart including coronary arteries. Fever was most common presentation, found 18 (85.7%) patients. All had marked...

Abstract Influenza, a significant cause of seasonal morbidity and mortality, can lead to severe complications affecting multiple organ systems. This case series highlights the diverse manifestations influenza-related dysfunction in children such as myocarditis, acute respiratory distress syndrome, kidney injury, necrotizing encephalopathy, liver failure, influenza-associated encephalopathy. emphasizes critical need for early recognition aggressive management influenza cases, given potential...

Background: In developing countries, there is scarce data on paediatric critical care. This makes modification of practices to improve outcome, difficult. The above study was done highlight the lack facilities and concept pediatric in eastern part India so that management can lead better outcome critically ill children.Methods: A retrospective demography, clinical profile, diagnosis, treatment children admitted PICU Kalinga Institute Medical Sciences from January 2014 December 2015 done....

Following an asymptomatic or mildly symptomatic coronavirus disease (COVID-19), otherwise healthy children may develop serious manifestations in the form of cardiac, neurological, respiratory, gastrointestinal, and dermatologic dysfunction. Many such cases were being observed Odisha, eastern state India, have been reported from different health-care facilities. We related these unexplained to multisystem inflammatory syndrome associated with COVID-19 (MIS-C) planned this study.This...

Context: Though many studies have been conducted on the effect of chronic smoking pulmonary function test (PFT) and heart rate variability (HRV), no study has found a correlation between parameters so far.Aim: The aim was to if there correlation, any, PFT HRV.Settings Design: Thirty male subjects who were smokers at least 10 pack years another 30 nonsmoking healthy males included in matched for age, height, weight, body surface area.Materials Methods: HRV performed these statistically...

Background: Nosocomial infection, due to Candida, contracted in the pediatric intensive care unit (PICU), is emerging as a significant healthcare challenge. The incidence of non-albicans Candida cause candidemia on rise, unlike previous decades. Materials and Methods: All cases confirmed by culture, admitted PICU during study period January 2017 December 2019, were retrospectively studied. prevalence, speciation, sensitivity pattern risk factors mortality recorded analyzed. Results: There...

Background: Scrub typhus was unseen in Odisha, but during postmonsoon months of 2014, for the first time, 25 cases scrub were identified pediatric department Kalinga Institute Medical Sciences, Bhubaneswar. Objectives: This study aimed at analyzing demographic pattern, symptomatology, complications, and response to therapy, which will help medical fraternity early diagnosis management. Materials Methods: By retrospective analysis case records between September 2014 February 2015, children...

The pandemic caused by COVID-19 has left few countries untouched. It is a far-reaching implication on humankind, with children and adolescents, being no exception. Although the prevalence fatality are negligible among children, possible impact their psychological mental health cannot be disregarded. unprecedented change in way of living bound to having some consequences adolescents. experiences gathered childhood adolescence known contribute shaping physical, emotional, social well-being...

Immune hemolytic anemia (IHA) is an uncommon adverse effect of a wide variety drugs.The incidence on the rise due to extensive use nonsteroidal anti-inflammatory drugs (NSAID).Mefenamic acid most common among NSAIDs causing AIHA by autoimmune mechanism.We are presenting case three years old child presented with history dark colored urine, severe anemia, and jaundice after taking mefenamic for fever.Investigations revealed leucocytosis, hyperbilirubinemia, raised reticulocyte count, negative...

Abstract Inherited causes of cavernous venous sinus thrombosis (CVST) leading to stroke in infancy are rare. Methylenetetrahydrofolate reductase (MTHFR) gene mutation is one such cause. Polymorphism MTHFR, an essential enzyme Vitamin B12 metabolism, leads increase homocysteine levels. This a prothrombotic state and, therefore, pediatric stroke. Children with the MTHFR have elevated The index case polymorphism CVST stoke had normal level. association A1298C can be confirmed only after further...

Abstract: The most common self-limiting viral infection of the lower respiratory tract in pediatric population is bronchiolitis, which commonly affects infants. In cases, syncytial virus (RSV) causative agent. general, recovery occurs within 5–7 days without any complications. Spontaneous pneumothorax one rare and less-reported complications bronchiolitis. We report a case male child aged 5 months with bilateral spontaneous (PNO) subcutaneous emphysema following nasopharyngeal swab was...

Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiographic entity of heterogeneous etiologies having similar clinical and neuroimaging features. Pediatric data are sparse, making early diagnosis challenging, which needs high index suspicion. So, we conducted this study to evaluate clinico-radiological features, associated risk factors, etiology, outcome in children.This retrospective case series patients, diagnosed as PRES followed up at tertiary care hospital Eastern...

Abstract Background Multi System Inflammatory Syndrome in children (MIS-C) associated with COVID-19 is a recently recognised potentially life-threatening entity. There limited data on post MIS-C sequelae. Methods 21 fulfilling the WHO criteria for were included our study. Data was collected at baseline and 12-16 weeks discharge to look any persistent sequelae mainly relating lungs or heart including coronary arteries Results Fever most common presentation, found 18 (85.7%) patients. All had...

Kearns–Sayre syndrome (KSS) is a rare mitochondrial disease was first described in 1958. The characteristic triad age of onset less than 20 years, progressive external ophthalmoplegia, pigmentary retinopathy, prevalence rate KSS nearly 1–3 per 100 000 individuals. Here, we report case 11-year-old male with KSS.

Diabetic ketoacidosis is an acute life-threatening complication of type 1 diabetes. Sometimes it the first presentation in undiagnosed child. Severe respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) and diabetes mellitus are very much interrelated as associated with increased risk severe COVID19 at same time, many cases new-onset had been diagnosed. Hyperglycemia, metabolic acidosis, ketonemia classical presentations. It essential to correct acidosis fluid correction insulin...

STRUCTURED ABSTRACT INTRODUCTION Following an asymptomatic or mildly symptomatic Corona virus disease (COVID 19), otherwise healthy children, may develop serious manifestations in form of cardiac, neurological, respiratory, gastrointestinal and dermatologic dysfunction. Many such cases were being observed Odisha, eastern state India reported from different health care facilities. We related these unexplained to Multisystem Inflammatory Syndrome associated with COVID 19 (MIS-C) planned this...

Presently, the market is flooded with different oral iron salt preparations. Most formulations marketed in India as hematinics contain not just iron, folic acid, vitamin B12, and C, but also other B complex vitamins trace elements. The rationality of such combinations questionable. purpose this article to help clinicians choosing an ideal preparation for treatment deficiency anemia. Therefore, we extensively reviewed various index journals. It was found that, still conventional preparations...

Currently, we have a shortage of comprehensive information about newer antiepileptic drugs (AEDs) in the pediatric population. This might explain discrepancies among pediatricians' preferences this regard. Therefore, it is crucial to study multifaceted impacts these on children. The endpoints our were non-AED predictors requirement combination therapy for seizure management, seizure-free period >6 months and >12 months, change Quality Life Childhood Epilepsy Questionnaire - 55 (QOLCE-55),...