Xinliang Lu

ORCID: 0000-0003-2511-5632
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Research Areas
  • Gastrointestinal disorders and treatments
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal Tumor Research and Treatment
  • Pancreatitis Pathology and Treatment
  • Liver Disease Diagnosis and Treatment
  • Eosinophilic Disorders and Syndromes
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Antifungal resistance and susceptibility
  • Inflammatory Myopathies and Dermatomyositis
  • Eosinophilic Esophagitis
  • Vitamin C and Antioxidants Research
  • Galectins and Cancer Biology
  • Soft tissue tumor case studies
  • Vasculitis and related conditions
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Internet of Things and Social Network Interactions
  • Myofascial pain diagnosis and treatment
  • Mast cells and histamine
  • Gallbladder and Bile Duct Disorders
  • Blood disorders and treatments
  • Gastroesophageal reflux and treatments
  • Abdominal vascular conditions and treatments
  • Lymphatic Disorders and Treatments
  • Advances in Oncology and Radiotherapy

Anhui University of Traditional Chinese Medicine
2025

Zhejiang University
2002-2025

Second Affiliated Hospital of Zhejiang University
2004-2024

Beihang University
2022

Xuan Wu Hospital of the Capital Medical University
2022

China-Japan Friendship Hospital
2014-2020

Peking Union Medical College Hospital
2013

Chinese Academy of Medical Sciences & Peking Union Medical College
2013

Tokyo Medical University
2008

Beth Israel Deaconess Medical Center
2008

Plenty of studies have assessed the association between intestinal metaplasia (IM) and gastric cancer risk, while results were inconsistent. We aimed to assess risk among patients with IM. Systematic literature searches conducted in PubMed, Embase Cochrane databases. Baseline characteristics outcomes from included extracted independently by two investigators. Either a fixed-effects or random-effects model was used composite pooled OR for risk. Finally, total 21 studies, which comprised...

10.1002/ijc.31571 article EN International Journal of Cancer 2018-04-30

Summary Dermatomyositis (DM) and polymyosits (PM) are systemic autoimmune diseases whose pathogeneses remain unclear. Neutrophil extracellular traps (NETs) reputed to play an important role in the pathogenesis of diseases. This study tests hypothesis that NETs may be pathogenic DM/PM. Plasma samples from 97 DM/PM patients (72 DM, 25 PM) 54 healthy controls were tested for capacities induce degrade NETs. DNase I activity was further explore possible reasons incomplete degradation Results 35...

10.1111/cei.12319 article EN Clinical & Experimental Immunology 2014-03-11

Mucormycosis usually presents as a progressive infection with significant angio-invasion. due to Mucor irregularis (formerly Rhizomucor variabilis var. variabilis), however, is exceptional in causing chronic cutaneous immunocompetent humans, ultimately leading severe morbidity if left untreated. More than 90 % of the cases known date were reported from Asia, mainly China. The nearest neighbour M. saprobic species hiemalis. aim this study was evaluate taxonomic position, epidemiology, and...

10.3767/003158513x665539 article EN Persoonia - Molecular Phylogeny and Evolution of Fungi 2013-03-30

Interstitial lung disease (ILD) is one of the most common and devastated complication polymyositis/dermatomyositis (PM/DM). Several studies have focused on serum biomarkers for ILD in PM/DM patients; however, there been no prospective studies.To explore compare predictive value four markers development patients with PM/DM.One hundred adult were included this clinical study at baseline. Forty-four without followed up 1 year. Fifty-six treated 2 months. Serum samples analysed levels Krebs von...

10.1111/imj.12754 article EN Internal Medicine Journal 2015-04-01

Endoscopic submucosal excavation (ESE) is a less invasive therapeutic alternative to surgical resection for the removal of gastric tumors [1]. The conventional procedural steps this technique all involve cautery markings delineate target lesion, followed by injection and lesion using hook knife, insulation-tipped or dual finally, closure mucosal incision clips [2]. We report novel variant ESE technique, snare resection-endoscopic (MSR-ESE), lower technical burden shorter procedure time...

10.1055/a-2261-7532 article EN cc-by Endoscopy 2024-02-22

Purpose: Because previous studies have reported depleted antioxidant capacity in patients with chronic pancreatitis (CP), prevention of free radical production has gained importance antifibrotic treatment strategies for CP.The aim this study was to investigate the effects ascorbic acid on oxidative and pancreatic damage experimental CP.Materials Methods: CP induced male Sprague-Dawley rats by infusion dibutyltin dichloride (DBTC) into tail vein.Ascorbic given intraperitoneally at a daily...

10.3349/ymj.2007.48.6.1028 article EN cc-by-nc Yonsei Medical Journal 2007-01-01

X. Gong, Lu, Wu, R. Xu, Q. Tang, G. L. Wang, Zhang and Zhao Role of bone marrow imprints in haematological diagnosis: a detailed study 3781 cases Objectives: To explore the role routine (BM) diagnosis. Methods: The cellularity diagnostic accuracy BM imprints, aspirate smears trephine biopsy sections from patients were assessed using cytochemical staining. Seventy‐nine lymphoma 114 plasma cell myeloma (PCM) selected for correlation analysis tumour infiltration patterns. Another 21 to detect...

10.1111/j.1365-2303.2010.00825.x article EN Cytopathology 2010-12-03

Hepatic fibrosis is defined as a pathological process, and activation of hepatic stellate cells (HSCs) believed to be the key event liver fibrosis. Additionally, activated HSCs may participate in formation tumor microenvironment. Polaprezinc, protector gastric mucosa, has been recently demonstrated an inhibitor mouse model. Proliferation colony assays were performed determine inhibitory effects polaprezinc on growth LX‑2 hepG2 cells. A migration assay was used evaluate change mobility...

10.3892/mmr.2017.7262 article EN Molecular Medicine Reports 2017-08-16

This study aimed to compare the radiologic size of gastric gastrointestinal stromal tumors (GISTs) on computed tomography (CT) with pathologic in a Chinese population, and elucidate potential significance CT preoperative risk stratification.The enrolled 314 patients treated by endoscopic/surgical resection lesions that proved postoperatively be GISTs. Bland-Altman analysis intraclass correlation coefficient (ICC) were adopted assess agreement between pathology. Independent predictors...

10.1016/j.ejso.2022.01.007 article EN cc-by-nc-nd European Journal of Surgical Oncology 2022-01-10

Background: The potential to predict pancreatic necrosis within the first 48 h by using plasma soluble thrombomodulin (sTM) in 104 patients with acute pancreatitis (AP) was analyzed a prospective 5-year investigation performed at single institution. Methods: According Balthazar CT grade, classified as no 72 patients, one-third necrotic 18 one-half 10 and more than 4 patients. Blood collected hours after onset of pain for sTM. Results: In healthy volunteers, levels TM were 16.49±5.24 μg/L. By...

10.2169/internalmedicine.46.6320 article EN Internal Medicine 2007-01-01

AIM: To investigate the presence of H.pylori DNA within gastric epithelial cells in patients with infection and its possible carcinogenic mechanism.METHODS: Total 112 patients, pathologically confirmed chronic superficial gastritis, atrophic intestinal metaplasia, atypical hyperplasia or cancer were studied.Among them, 28 negative 84 positive.H.pylori was detected by GenPoint catalyzed signal amplification system for situ hybridization.CONCLUSION: exists both nucleus cytoplasm infections.The...

10.3748/wjg.v8.i2.305 article EN cc-by-nc World Journal of Gastroenterology 2002-01-01

Abstract Background Henoch-Schönlein purpura (HSP) is a systemic small-vessel vasculitis, and its association with inflammatory bowel disease (IBD) has been the focus of considerable research. Despite numerous studies, it remains uncertain whether in which direction causal relationships exist between HSP IBD. To reveal IBD, we conducted bidirectional two-sample Mendelian randomization analysis using publicly available genome-wide study (GWAS) summary statistics. Methods We obtained...

10.1093/ecco-jcc/jjad212.1331 article EN Journal of Crohn s and Colitis 2024-01-01

To investigate the distribution of H.pylori antigens in gastric mucosa patients with infection, and relationship between cancer.Of 112 confirmed by pathological study to have chronic superficial gastritis, precancerous changes (chronic atrophic intestinal metaplasia or atypical hyperplasia) cancer, 28 were negative 84 positive. detected immunohistochemistry.The positive group, comprised 12 22 (50.0%) gastritis 25 (88.0%) group 13 35 (37.1%) cancer group. The rates cytoplasm progressively...

10.1007/bf02840931 article EN PubMed 2004-02-01
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