Jing Chen

ORCID: 0000-0003-1287-1930
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Genetic and phenotypic traits in livestock
  • Cancer-related molecular mechanisms research
  • Epigenetics and DNA Methylation
  • Plant Molecular Biology Research
  • Seed Germination and Physiology
  • Genetic Associations and Epidemiology
  • Hormonal Regulation and Hypertension
  • Electrolyte and hormonal disorders
  • Genetics and Plant Breeding
  • Allelopathy and phytotoxic interactions
  • Renal function and acid-base balance
  • Research in Cotton Cultivation
  • Cancer-related gene regulation
  • Cooperative Communication and Network Coding
  • Genetic diversity and population structure
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Cytomegalovirus and herpesvirus research
  • Genomics, phytochemicals, and oxidative stress
  • Pediatric health and respiratory diseases
  • Polysaccharides and Plant Cell Walls
  • Lung Cancer Treatments and Mutations
  • Plant and Fungal Interactions Research
  • Radiomics and Machine Learning in Medical Imaging

Huazhong University of Science and Technology
2025

Tongji Hospital
2025

Zhejiang Wanli University
2025

University of Leicester
2021-2024

Zhejiang Chinese Medical University
2009-2024

Kunming Medical University
2020-2024

Huzhou Central Hospital
2024

Central South University
2009-2024

Shanghai Jiao Tong University
2018-2024

Sichuan University
2014-2024

In plants, basic leucine zipper (bZIP) proteins regulate numerous biological processes such as seed maturation, flower and vascular development, stress signalling pathogen defence. We have carried out a genome-wide identification analysis of 125 bZIP genes that exist in the maize genome, encoding 170 distinct proteins. This family can be divided into 11 groups according to phylogenetic relationship among those Arabidopsis rice. Six kinds intron patterns (a–f) within hinge regions are...

10.1093/dnares/dss026 article EN cc-by-nc DNA Research 2012-10-26

The WRKY transcription factors function in plant growth and development, response to the biotic abiotic stresses. Although many studies have focused on functional identification of factors, much less is known about molecular phylogenetic global expression analysis complete family maize. In this study, we identified 136 proteins coded by 119 genes B73 inbred line from genome named them an orderly manner. Then, a comprehensive five species was performed explore origin evolutionary patterns...

10.1093/dnares/dsr048 article EN DNA Research 2012-01-24

In situ monitoring of tissue regeneration progression is primary importance to basic medical research and clinical transformation. Despite significant progress in the field engineering regenerative medicine, few technologies have been established inspect process. Here, we present an integrated second near-infrared (NIR-II, 1000-1700 nm) window vivo imaging strategy based on 3D-printed bioactive glass scaffolds doped with NIR-II ratiometric lanthanide-dye hybrid nanoprobes, allowing for early...

10.1021/acs.nanolett.1c04356 article EN Nano Letters 2022-01-10

Understanding the DNA methylome and its relationship with non-coding RNAs, including microRNAs (miRNAs) long RNAs (lncRNAs), is essential for elucidating molecular mechanisms underlying key biological processes in plants. Few studies have examined functional roles of grass species highly heterozygous polyploid genomes.We performed genome-wide methylation profiling tetraploid switchgrass (Panicum virgatum L.) cultivar 'Alamo' using bisulfite sequencing. Single-base-resolution patterns were...

10.1186/s13068-018-1202-0 article EN cc-by Biotechnology for Biofuels 2018-07-24

The Kaiser Permanente & Strategic Partners Patient Outcomes Research To Advance Learning (PORTAL) network engages four healthcare delivery systems (Kaiser Permanente, Group Health Cooperative, HealthPartners, and Denver Health) their affiliated research centers to create a new national infrastructure that builds on existing relationships among these institutions. PORTAL is enhancing its current capabilities by expanding the scope of common data model, paying particular attention...

10.1136/amiajnl-2014-002746 article EN cc-by-nc Journal of the American Medical Informatics Association 2014-05-13

This study examines the utility of morphology and DNA barcoding in species identification freshwater fishes from north-central Nigeria. We compared molecular data (mitochondrial cytochrome c oxidase subunit I (COI) sequences) 136 de novo samples 53 morphologically identified alongside others GenBank BOLD databases. Using sequence similarity-based (≥97% cutoff) technique, 50 (94.30%) 24 (45.30%) were to level using databases, respectively. Furthermore, we cases taxonomic problems 26 (49.00%)...

10.1002/ece3.4210 article EN cc-by Ecology and Evolution 2018-06-13

Plant Architecture Related Traits (PATs) are of great importance for maize breeding, and mainly controlled by minor effect quantitative trait loci (QTLs). However, cloning or even fine-mapping QTLs is very difficult in maize. Theoretically, large population high density genetic map can be helpful increasing QTL mapping resolution accuracy, but such a possibility have not been actually tested.Here, we employed genotyping-by-sequencing (GBS) strategy to construct linkage with 16,769 marker...

10.1186/s12870-018-1233-5 article EN cc-by BMC Plant Biology 2018-01-18

The anterior cingulate cortex (ACC) is a critical hub for nociceptive perception and pain-related anxiety. Long-term synaptic plasticity in ACC was found to be important chronic inflammatory pain As short-term plasticity, depolarization-induced suppression of excitation (DSE) involved several conditions, such as stress, epilepsy, autism. However, it still unknown whether DSE the central sensitization Using whole-cell patch clamp, calcium imaging, western blot, behavioral testing, we that...

10.1093/cercor/bhx117 article EN Cerebral Cortex 2017-05-11

Genome-wide association studies are a powerful approach for identifying genes related to complex traits in organisms, but limited by the requirement reference genome sequence of species under study. To circumvent this problem, we propose transcriptome-referenced study (TRAS) that utilizes transcriptome generated single-molecule long-read sequencing as score population variation at both transcript and expression levels. Candidate transcripts identified when scores associated with trait their...

10.1093/dnares/dsy027 article EN cc-by-nc DNA Research 2018-07-25

Abstract Thyroid hormones play a critical role in regulation of multiple physiological functions and thyroid dysfunction is associated with substantial morbidity. Here, we use electronic health records to undertake genome-wide association study thyroid-stimulating hormone (TSH) levels, total sample size 247,107. We identify 158 novel genetic associations, more than doubling the number known associations TSH, implicate 112 putative causal genes, which 76 are not previously implicated. A...

10.1038/s41467-023-42284-5 article EN cc-by Nature Communications 2023-10-23
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