A5034551256- Image Retrieval and Classification Techniques
- Hand Gesture Recognition Systems
- Handwritten Text Recognition Techniques
- Retinal Development and Disorders
- Cellular and Composite Structures
- Face and Expression Recognition
- Retinal Diseases and Treatments
- Mechanical Behavior of Composites
- Generative Adversarial Networks and Image Synthesis
- Natural Fiber Reinforced Composites
- Glaucoma and retinal disorders
- Tropical and Extratropical Cyclones Research
- Video Analysis and Summarization
- Plant Pathogens and Fungal Diseases
- Gaze Tracking and Assistive Technology
- Simulation and Modeling Applications
- Neural Networks and Applications
- Sperm and Testicular Function
- Ocean Waves and Remote Sensing
- Image Enhancement Techniques
- Biometric Identification and Security
- Multimodal Machine Learning Applications
- Advanced Computational Techniques and Applications
- Anesthesia and Pain Management
- Hydrology and Sediment Transport Processes
Tianjin University
2025
University of Chinese Academy of Sciences
2020-2024
National University of Defense Technology
2022-2024
Shanghai Institute of Organic Chemistry
2024
Ningbo University
2024
Jinan City People's Hospital
2014-2023
Xiamen University
2023
Shandong First Medical University
2014-2023
Shenzhen Institutes of Advanced Technology
2023
Chinese Academy of Sciences
2023
Retinal pigment epithelial (RPE) degeneration is potentially involved in the pathogenesis of several retinal degenerative diseases.mTORC1 signaling shown as a crucial regulator many biological processes and disease progression.In this study, we aimed at investigating role mTORC1 RPE degeneration.Methods: Western blots were conducted to detect expression pattern during degeneration.Cre-loxP system was used generate RPE-specific activation mice.Fundus, immunofluorescence staining, transmission...
Defects in energy metabolism either the retina or immediately adjacent retinal pigment epithelium (RPE) underlie degeneration, but metabolic dependence between and RPE remains unclear. Nitrogen-containing metabolites such as amino acids are essential for metabolism. Here, we found that 15N-labeled ammonium is predominantly assimilated into glutamine both RPE/choroid ex vivo [15N]Ammonium tracing show that, like brain, can synthesize asparagine from ammonium, liver cannot. However, unless...
In this paper, a novel weightlessness feature for activity recognition from tri-axial acceleration signals have been proposed. Since the orientation between accelerometer and userpsilas body may continuously change when user perform activities, we propose an algorithm to calibrate actual vertical direction of signal through estimating gravitational direction. We combine peaks produce six dimensional weightlessness-based features recognition. Classification activities is performed with...
Retinal pigment epithelial (RPE) is primarily impaired in age-related macular degeneration (AMD), leading to progressive loss of photoreceptors and sometimes choroidal neovascularization (CNV). mTOR has been proposed as a promising therapeutic target, while the usage its specific inhibitor, rapamycin, was greatly limited. To mediate pathway retina by noninvasive approach, we developed novel biomimetic nanocomplexes where rapamycin-loaded nanoparticles were coated with cell membrane derived...
The "missing" link of complex and multifaceted interplay among endogenous retroviruses (ERVs) transcription, chronic immuno-inflammation, the development psychiatric disorders is still far from being completely clarified. present study was aimed to investigate mechanism protective role inhibiting ERVs on reversing microglial immuno-inflammation in basolateral amygdala (BLA) stress-induced negative emotional behaviors mice.Male C57BL/6 mice were exposed unpredictable mild stress (CUMS) for 6...
A new crush trigger, called crown is introduced at one end of carbon-fibre-reinforced polymer circular tubes. Quasi-static compression tests are performed on the tubes to investigate their energy absorption characteristics. It observed that all crushed in a brittle fracturing mode. Both trigger and bevel can effectively control position crushing initiation, reduce peak load increase stability. also found tube wall each specimen delaminated mainly into three layers. The relatively intact...
Isocitrate dehydrogenase 3 (IDH3) is a key enzyme in the mitochondrial tricarboxylic acid (TCA) cycle, which catalyzes decarboxylation of isocitrate into α-ketoglutarate and concurrently converts NAD+ NADH. Dysfunction IDH3B, β subunit IDH3, has been previously correlated with retinal degeneration male infertility humans, but tissue-specific effects IDH3 dysfunction are unclear. Here, we generated Idh3b-KO mice found that IDH3B essential for activity multiple tissues. We determined loss...
Asiatic acid (AA), a pentacyclic triterpene derived from the tropical medicinal plant Centella asiatica, has been widely used as an antioxidant and anti-inflammatory agent. Evidence regarding neuroprotective properties of AA is emerging. However, protective effects its mechanism in glaucoma are poorly understood. In current study, we investigate effect on retinal ganglion cells (RGCs) rat model glaucoma. Elevated intraocular pressure (IOP) was induced adult rats by injecting microspheres...
Abstract Retinoblastoma (RB) is the most common pediatric intraocular malignancy and a serious vision- life-threatening disease. The biallelic mutation of retinoblastoma gene RB1 initial event in malignant transformation RB, but exact molecular mechanism still unclear. E2F transcription factors can be activated by loss function lead to uncontrolled cell division. Among family numbers, E2F1 has higher expression abundance than E2F2 E2F3 RB clinical samples. By integrating ChIP-seq data,...
The significance of glomerular IgM deposit intensity in IgA Nephropathy (IgAN) remained ambiguous and requires further research. Patients with biopsy-proven IgAN our hospital from January 2018 to May 2023 were recruited into this retrospective single-center study. who presented positive included + cohort while patients negative IgM– cohort. Of the IgM+, whose IF deposits exceeded 1+ formed IgM-H was equal consisted IgM-L Pairwise comparisons performed among these cohorts determine clinical...
A novel video-based finger writing virtual character recognition system (FVCRS) is described in this paper. With FVCR system, one can enter characters into a computer by just using the movement of fingertip, without any additional device such as keyboard or digital pen. This provides new wireless character-inputting method. simple but effective background model built for segmenting human-finger movements from cluttered background. robust fingertip detection algorithm based on feature...
This paper proposes a gesture recognition system based on single tri-axis accelerometer mounted cell phone for human computer interaction (HCI). Three feature extraction methods, namely discrete cosine transform (DCT), Fast Fourier (FFT) and hybrid approach which combine wavelet packet decomposition (WPD) with are proposed. Recognition of the gestures is performed Support Vector Machine (SVM). results acceleration data collect from 67 subjects. The best average result (87.36%) 17 complex...
A trial was conducted to verify the effect of hydrogen cyanamide (HC) application on endodormancy release and blooming 'Summit' sweet cherry trees, as well endogenous gibberellic acids (GAs) abscisic acid (ABA) levels which were identified quantified by gas chromatography/mass spectrometry in branches with spurs. Results showed that HC efficiently hastened budbreak, shortened duration improved fruit set. Furthermore, bioactive GAs play different roles process blooming. GA3 recognised highest...