Lars J. Petersen

ORCID: 0000-0003-2519-983X
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About
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Research Areas
  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Radiopharmaceutical Chemistry and Applications
  • Medical Imaging Techniques and Applications
  • Pain Mechanisms and Treatments
  • Allergic Rhinitis and Sensitization
  • Radiomics and Machine Learning in Medical Imaging
  • Bone health and treatments
  • Advancements in Transdermal Drug Delivery
  • Dermatology and Skin Diseases
  • Diagnosis and Treatment of Venous Diseases
  • Thermoregulation and physiological responses
  • Venous Thromboembolism Diagnosis and Management
  • Medical Imaging and Pathology Studies
  • Peripheral Artery Disease Management
  • Contact Dermatitis and Allergies
  • Drug-Induced Adverse Reactions
  • Education, Healthcare and Sociology Research
  • Infrared Thermography in Medicine
  • Asthma and respiratory diseases
  • Renal and Vascular Pathologies
  • Mast cells and histamine
  • Urticaria and Related Conditions
  • Genital Health and Disease
  • Lymphoma Diagnosis and Treatment

Aalborg University
2014-2025

Aalborg University Hospital
2014-2023

Cancer Research Center
2015-2022

Klinik und Poliklinik für Nuklearmedizin
2021

Deutsche Klinik für Diagnostik
2018-2019

Rigshospitalet
1990-2018

Regionshospitalet Viborg
2006-2017

Aarhus University
1997-2017

Regionshospitalet Herning
2017

Aarhus University Hospital
2017

1 Physical activity is known to increase type I collagen synthesis measured as the concentration of biomarkers in plasma. By use microdialysis catheters with a very high molecular mass cut-off value (3000 kDa) we aimed determine local and degradation peritendinous region by measuring interstitial concentrations propeptide (PICP; 100 product (ICTP; 9 well an inflammatory mediator (PGE2). 2 Seven trained human runners were studied before after (2 72 h) 3 h running (36 km). Two placed space...

10.1111/j.1469-7793.1999.00299.x article EN The Journal of Physiology 1999-11-01

Abstract Objective Interleukin‐15 (IL‐15) is a proinflammatory, innate response cytokine that mediates pleiotropic effector function in rheumatoid arthritis (RA) inflammatory synovitis. Our objective was to study the ability of HuMax‐IL15, human IgG1 anti–IL‐15 monoclonal antibody, neutralize exogenous and endogenous IL‐15 activity vitro perform phase I–II dose‐escalation trial with HuMax‐IL15 patients active RA. Methods Mononuclear cells from blood synovial fluid (SF) RA were isolated...

10.1002/art.21249 article EN Arthritis & Rheumatism 2005-09-01

10.1016/j.chemolab.2004.09.013 article EN Chemometrics and Intelligent Laboratory Systems 2004-12-30

The pulsatility index (PI) and the resistive (RI) are used as pulsed-wave Doppler measurements of downstream renal artery resistance. PI RI have been found to correlate with vascular resistance, filtration fraction effective plasma flow in chronic failure. aim present study was evaluate potential relationship between these indices rate decline function, reflected by changes different parameters function patients failure.Twenty-one (8 females; 13 males, mean age 58 years (36-75)) failure were...

10.1093/ndt/12.7.1376 article EN Nephrology Dialysis Transplantation 1997-07-01

<h3>Abstract</h3> <b>Objective</b> To determine if the macrolide clarithromycin affects mortality and cardiovascular morbidity in patients with stable coronary heart disease. <b>Design</b> Centrally randomised multicentre trial. All parties at all stages were blinded. Analyses by intention to treat. <b>Setting</b> Five Copenhagen University cardiology departments a coordinating centre. <b>Participants</b> 13 702 aged 18 85 years who had discharge diagnosis of myocardial infarction or angina...

10.1136/bmj.38666.653600.55 article EN BMJ 2005-12-08

The mediator mechanisms of the cutaneous wheal and flare response, which underlies allergic skin urticarial conditions, are controversial. results primarily from a direct effect histamine on local vascular bed but to what extent does diffuse within wheal? is neurogenic, in origin, being disseminated dermis by axon reflexes, do neuropeptides released nerve endings cause vasodilatation directly or they induce further release then transduces flare?We have addressed these questions inserting 216...

10.1046/j.1365-2222.1997.d01-502.x article EN Clinical & Experimental Allergy 1997-03-01

Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of aggressive non-Hodgkin lymphomas with poor outcomes on current therapy. We investigated whether response assessed PET/CT combined baseline total metabolic tumor volume (TMTV) could detect early relapse or refractory disease. <b>Methods:</b> From 7 European centers, 140 patients nodal PTCL who underwent were selected. Forty-three had interim PET (iPET) performed after 2 cycles (iPET2), 95 iPET 3 4 (iPET3/4), and 96 end-of-treatment...

10.2967/jnumed.117.193946 article EN Journal of Nuclear Medicine 2017-09-01

To investigate the added value and diagnostic accuracy of 68Ga-PSMA PET/CT versus bone scintigraphy (BS) for metastasis detection at primary staging prostate cancer (PCa).Inclusion criteria involved consecutive patients with newly diagnosed intermediate- to high-risk PCa, who had undergone BS, mostly supplementary SPECT/low-dose CT, 68Ga-PSMA-11 within less than 3 months without therapy initiation between two investigations. BS was evaluated according clinical routine reported as no...

10.1186/s13550-020-00618-0 article EN cc-by EJNMMI Research 2020-04-08

10.1007/s12268-025-2391-2 article DE BIOspektrum 2025-03-01

Background Activation of mast cells and systemic release histamine are major side effects intravenously administered muscle relaxants. In the current study, dermal microdialysis was used for investigation cell activation by Dermal enabled simultaneous assessment mediator release, vascular reactions, sensory induced intradermal application relaxants without effects. Methods Succinylcholine, isoquinolines cisatracurium, atracurium, mivacurium, steroids pancuronium, vecuronium, rocuronium,...

10.1097/00000542-200109000-00019 article EN Anesthesiology 2001-09-01
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