A5028815618- Advancements in Transdermal Drug Delivery
- Inhalation and Respiratory Drug Delivery
- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Chemistry and Chemical Engineering
- Hydrogels: synthesis, properties, applications
- Quinazolinone synthesis and applications
- Flavonoids in Medical Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Surgical Sutures and Adhesives
- Microwave-Assisted Synthesis and Applications
- Wound Healing and Treatments
- Synthesis and Biological Evaluation
- Curcumin's Biomedical Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Phytochemistry and biological activity of medicinal plants
- Drug Transport and Resistance Mechanisms
- MXene and MAX Phase Materials
- Pharmaceutical studies and practices
- Periodontal Regeneration and Treatments
- Neuroendocrine Tumor Research Advances
Future University in Egypt
2016-2023
St. John's University
2020-2021
There is growing evidence that repurposed drugs demonstrate excellent efficacy against many cancers, while facilitating accelerated drug development process. In this study, bedaquiline (BDQ), an FDA approved anti-mycobacterial agent, was and inhalable cyclodextrin complex formulation developed to explore its anti-cancer activity in non-small cell lung cancer (NSCLC). A sulfobutyl ether derivative of β-cyclodextrin (SBE-β-CD) selected based on phase solubility studies molecular modeling...
Abstract Background Baicalin is a natural compound having intriguing and useful pharmacological properties that may be used alone or in conjunction with other treatments variety of therapeutic areas. However, the drug has low aqueous solubility poor absorption. The aim this research was to optimize bioavailability baicalin through incorporation into solid lipid nanoparticles. Results particle size prepared baicalin-loaded nanoparticles ranged between 248.2 ± 1.72 nm 291.9 30.9 nm. speed,...
Recently, the occurrence of cancer has significantly increased; it represents second-most frequent cause death after cardiovascular diseases. Many dietary antioxidants have shown large impact as effective agents for prevention by reducing oxidative stress, which been a part in development many diseases, including cancer. One obstacles delivery antioxidant therapies into required domain lies inadequate these to their intended site action. Using nanotechnology leads increased therapeutic index...
Aim: A high throughput ultra-performance liquid chromatography (UPLC)-ultraviolet method for quantification of nintedanib in rat and human plasma was developed optimized using chemometrical approach. Method: Design experiment multivariate statistical approach used definition method. Final separation performed protein precipitation on ACQUITY HSS T3 C18 column isocratic mode potassium phosphate buffer (pH 7.5): acetonitrile. Results: Method validated as per US-FDA guidelines linearly from...
Recent studies proved that the symptoms of bronchial asthma follow circadian rhythms and become worse in early morning. In such cases, conventional sustained-release treatment regimens are inappropriate for delivery antiasthmatic drugs as they cannot be administrated just prior to worsening symptoms. The current work aimed explore pharmacokinetics a model drug following oral administration chronotherapeutic system six healthy volunteers. A sensitive selective chromatoghraphic method was used...