A5075785553- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Advanced Drug Delivery Systems
- 3D Printing in Biomedical Research
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Lipid metabolism and disorders
- Drug Solubulity and Delivery Systems
- Tissue Engineering and Regenerative Medicine
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Glaucoma and retinal disorders
- Erythrocyte Function and Pathophysiology
- Sepsis Diagnosis and Treatment
- Allergic Rhinitis and Sensitization
- Peroxisome Proliferator-Activated Receptors
- Extracellular vesicles in disease
- Immune responses and vaccinations
- Microfluidic and Bio-sensing Technologies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Air Quality Monitoring and Forecasting
- Pharmacological Effects and Assays
- Neuroscience of respiration and sleep
- Occupational exposure and asthma
- PI3K/AKT/mTOR signaling in cancer
Texas Tech University Health Sciences Center
2012-2024
Texas Tech University
2012-2024
Regeneron (United States)
2021-2022
Smt. N.H.L. Municipal Medical College
2019
CHI Health Creighton University Medical Center - Bergan Mercy
2009
Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering intraocular pressure (IOP), risk factor for glaucoma, but most treatments do not directly target the pathological changes to increased IOP, which can manifest as medication resistance disease progresses. To identify physiological modulators we performed genome- and exome-wide association analysis in >129,000 individuals with IOP measurements extended these findings an risk. We report identification...
Development of lung models for testing a drug substance or delivery system has been an intensive area research. However, model that mimics physiological and anatomical features human lungs is yet to be established. Although in vitro models, developed fine-tuned over the past few decades, were instrumental development many commercially available drugs, they are suboptimal reproducing microenvironment complex anatomy lungs. Similarly, intersubject variability high costs have major limitations...
Heparin-like compounds interrupt leukocyte adhesion and migration, prevent release of chemical mediators during the process inflammation. However, little is known whether anti-inflammatory property smaller heparin fragments, low-molecular-weight (LMWH), plays any role in airway In this study, we sought to evaluate efficacy LMWH-loaded large porous polyethylene glycol-poly(D,L-lactide-co-glycolide) (PEG-PLGA) particulate formulations alleviating cellular biochemical changes associated with...
Objectives: To determine the discriminative ability of PRISM III scoring system in predicting mortality children admitted to PICU.Methods: Prospective observational study all 1 month 12 years age PICU during July2017 June2018.Result: Out 250 patients PICU, 133 were male & 117 female. In group months, 30(22.22%) expired while months years,18(11.65%) expired. Due respiratory involvement, was 24(16.43%), due central nervous 8(17.39%) and septicemia 12(46.15%) . At hours admission, 214 had score...
Abstract Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering intraocular pressure (IOP), risk factor for glaucoma, but most treatments do not directly target the pathological changes to increased IOP, which can manifest as medication resistance disease progresses. To identify physiological modulators we performed genome- and exome-wide association analysis in >129,000 individuals with IOP measurements extended these findings an risk. We report...