- Celiac Disease Research and Management
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Asthma and respiratory diseases
- Microscopic Colitis
- Aortic Disease and Treatment Approaches
- Eosinophilic Esophagitis
- Congenital Heart Disease Studies
- Pericarditis and Cardiac Tamponade
- Health disparities and outcomes
- Cardiomyopathy and Myosin Studies
- Helicobacter pylori-related gastroenterology studies
- Air Quality and Health Impacts
- Kawasaki Disease and Coronary Complications
- Neonatal Respiratory Health Research
- Respiratory and Cough-Related Research
- Gastrointestinal disorders and treatments
- Digestive system and related health
- Climate Change and Health Impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Inhalation and Respiratory Drug Delivery
- Aortic aneurysm repair treatments
- Cardiac Imaging and Diagnostics
- Noise Effects and Management
Mayo Clinic in Florida
2016-2025
Mayo Clinic
2016-2025
Mayo Clinic in Arizona
2016-2025
Department of Medical Sciences
2019-2020
WinnMed
2020
The Alfred Hospital
2017
London Chest Hospital
1992-1993
Royal London Hospital
1992
Celiac disease (CD) is a common immune-mediated disorder that affects up to 1% of the general population. Recent reports suggest incidence CD has reached plateau in many countries. We aim study and altered presentation childhood well-defined population.Using Rochester Epidemiology Project, we retrospectively reviewed Mayo Clinic Olmsted Medical Center medical records from January 1994 December 2014. identified all cases patients ages 18 years or younger at time diagnosis. Incidence rates...
Purpose The impact of postoperative complications on long-term survival is not well characterized. We sought to study the prevalence after cardiac surgery and their survival. Methods Operative survivors (n = 26,221) who underwent coronary artery bypass grafting (CABG) 13,054, 49.8%), valve 8667, 33.1%) or combined CABG 4500, 17.2%) from 1993 2019 were included in study. Records reviewed for Propensity-match analysis was performed between patients did have a complication. associations...
Importance Little is known about the burden and outcomes of respiratory syncytial virus (RSV)–positive acute infection (ARI) in community-dwelling older adults. Objective To assess incidence RSV-positive ARI before during COVID-19 pandemic, to for Design, Setting, Participants This was a community-based cohort study adults residing southeast Minnesota that followed up with 2325 aged 50 years or 2 RSV seasons (2019-2021) ARI. The assessed at 4 weeks, 6 7 months, 12 13 months after Exposure...
Summary Background Coeliac disease is a substantially underdiagnosed disorder, with clinical testing currently guided by case finding. Aim To determine the presence of indications for diagnostic and frequency in undiagnosed coeliac disease. Methods This was case‐control study adults without prior diagnosis Undiagnosed cases were identified through sequential serology, unaffected age‐ gender‐matched controls selected. Medical records systematically reviewed evidence testing. Results Of 47 557...
Rationale Clinical decision support (CDS) tools leveraging electronic health records (EHRs) have been an approach for addressing challenges in asthma care but remain under-studied through clinical trials. Objectives To assess the effectiveness and efficiency of Asthma-Guidance Prediction System (A-GPS), Artificial Intelligence (AI)-assisted CDS tool, optimizing management a randomized trial (RCT). Methods This was single-center pragmatic RCT with stratified randomization design conducted one...
Abstract Objective Artificial intelligence (AI) models may propagate harmful biases in performance and hence negatively affect the underserved. We aimed to assess degree which data quality of electronic health records (EHRs) affected by inequities related low socioeconomic status (SES), results differential AI across SES. Materials Methods This study utilized existing machine learning for predicting asthma exacerbation children with asthma. compared balanced error rate (BER) against...
OBJECTIVES: Children with multiple complex chronic conditions (MCCs) represent a small fraction of our communities but disproportionate amount health care cost and mortality. Because the temporal trends children MCCs within geographically well-defined US pediatric population has not been previously assessed, planning policy for this vulnerable is limited. METHODS: In population-based, repeated cross-sectional study, we identified enrolled all eligible residing in Olmsted County, Minnesota,...
There is a significant delay between symptom onset and diagnosis of childhood asthma, but the impact this on asthma outcomes has not been well understood. We sought to study association delayed with exacerbations (AEs) in children. Using Mayo Clinic birth cohort, we identified children from electronic health records. defined date as when subjects first met predetermined criteria ascertained by an records-based natural language processing algorithm. Delay (DD) was >30 days (vs timely [TD]...
Childhood asthma often continues into adulthood, but some children experience remission. Utilizing electronic health records (EHRs) to predict prognosis can aid care providers and patients in developing effective prioritized plans. We aimed develop artificial intelligence (AI) models using various clinical variables extracted from EHRs childhood (remission vs no remission) different age groups. developed AI utilizing patients' during the first 6, 9, or 12 years of their lives status at ages...
Limited literature is available on the best management strategy for tricuspid valve (TV) disease in adults. We sought to review our long-term outcomes of TV surgery with regard survival and reoperation.A retrospective analysis all patients ≥18 years age [n = 2541, aged 67 ± 13years, 1433 (56%) females] who underwent first-time between January 1993 December 2013 was done. There were 1735 received repair 806 replacement. A gradient boosting machine model used derive a propensity score...
Notification of tuberculosis is essential for local contact tracing and assessing the national incidence tuberculosis. The accuracy notification figures uncertain. This study examined rates all patients diagnosed as having at two hospitals in East End London over five years.In a retrospective survey aged 16 years or more presenting with to Chest Hospital Royal from 1 January 1985 31 December 1989, cases were identified microbiology histology records, statutory notifications, necropsy...
INTRODUCTION: Treated patients with celiac disease (CeD) and nonceliac gluten sensitivity (NCGS) report acute, transient, incompletely understood symptoms after suspected exposure. To determine whether (i) blinded exposure induces symptoms, (ii) subjects accurately identify exposure, (iii) serum interleukin-2 (IL-2) levels distinguish CeD from NCGS METHODS: Sixty (n = 20 treated, healed CeD; n treated NCGS; controls) were block randomized to a single, double-blind sham (rice flour) or 3-g...