A5058896809- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Surgical site infection prevention
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- COVID-19 epidemiological studies
- Herpesvirus Infections and Treatments
- Mycobacterium research and diagnosis
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Infection Control and Ventilation
- Influenza Virus Research Studies
- Pneumonia and Respiratory Infections
- Mechanical Circulatory Support Devices
- Urinary Tract Infections Management
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Central Venous Catheters and Hemodialysis
- Viral gastroenteritis research and epidemiology
- Infectious Diseases and Tuberculosis
- Antibiotics Pharmacokinetics and Efficacy
- Tuberculosis Research and Epidemiology
- Antibiotic Use and Resistance
Mayo Clinic in Florida
2016-2025
Mayo Clinic in Arizona
2014-2024
Mayo Clinic
2014-2023
WinnMed
2007-2023
Government Mohan Kumaramangalam Medical College
2018-2021
Museum of Heilongjiang Province
2021
Office of Infectious Diseases
2013-2019
Engineering Associates (United States)
2018
Mayo Clinic Hospital
2017
Associated Press
2014
A cluster of cases pneumonia caused by a novel coronavirus, COVID-19, was first reported in Wuhan the Hubei province China late December 2019. Since then, several thousand have been mainland China, with spread to over two dozen countries. Although many comparisons other coronavirus epidemics made, potential impact this is uncertain. We seek summarize what known about compare epidemic prior outbreaks, and provide primer on coronaviruses for practicing clinicians. Coronaviruses are widespread...
Abstract Objectives: Prolonged survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on environmental surfaces and personal protective equipment may lead to these transmitting this pathogen others. We sought determine the effectiveness a pulsed-xenon ultraviolet (PX-UV) disinfection system in reducing load SARS-CoV-2 hard N95 respirators. Methods: Chamber slides respirator material were directly inoculated with exposed different durations PX-UV. Results: For surfaces, for...
Importance Little is known about the burden and outcomes of respiratory syncytial virus (RSV)–positive acute infection (ARI) in community-dwelling older adults. Objective To assess incidence RSV-positive ARI before during COVID-19 pandemic, to for Design, Setting, Participants This was a community-based cohort study adults residing southeast Minnesota that followed up with 2325 aged 50 years or 2 RSV seasons (2019-2021) ARI. The assessed at 4 weeks, 6 7 months, 12 13 months after Exposure...
Tefibazumab (Aurexis), a humanized monoclonal antibody that binds to the surface-expressed adhesion protein clumping factor A, is under development as adjunctive therapy for serious Staphylococcus aureus infections. Sixty patients with documented S. bacteremia (SAB) were randomized and received either tefibazumab at 20 mg/kg of body weight single infusion or placebo in addition an antibiotic(s). The primary objective study was determining safety pharmacokinetics. An additional assess...
To assess the duration of shedding influenza A virus detected by polymerase chain reaction (PCR) and cell culture among patients hospitalized with infection.Mayo Clinic (Rochester, Minnesota) hospitals that cater to both community referral populations.Patients 18 years old older who were between December 1, 2004, March 15, 2005, a laboratory-confirmed (ie, PCR-based) diagnosis infection consecutively enrolled. Additional throat swab specimens collected at 2, 3, 5, 7 days after initial...
Abstract Ten case reports of disseminated Mycobacterium chimaera infections associated with cardiovascular surgery were published from Europe. We report 3 cases M histories aortic graft and/or valvular within the United States. Two patients demonstrated ocular involvement, a potentially important clinical finding.
Staphylococcus aureus is a leading cause of bacteremia in hospitalized patients. Whether or not S. (SAB) associated with clonality, implicating potential nosocomial transmission, has not, however, been investigated. Herein, we examined the epidemiology SAB using whole genome sequencing (WGS). 152 isolates collected over course 2015 at single large Minnesota medical center were studied. protein A (spa) typing was performed by PCR/Sanger sequencing; multilocus sequence (MLST) and core MLST...
ABSTRACT Introduction Vaccination is crucial to the thoracic solid organ transplant (SOT) population reduce vaccine‐preventable infection. However, data on posttransplant hepatitis B virus (HBV) vaccination compliance and vaccine‐induced seroprotection are lacking. Methods We conducted a retrospective study of adult (heart lung) recipients at Mayo Clinic sites in Minnesota, Arizona, Florida between January 2018 August 2023. Recombivax HB was used before 2020, Heplisav‐B preferred after 2020....
The objective of our study was to determine the incidence infectious complications common ultrasound-guided procedures including fine-needle aspiration (FNA), drain placement, biopsy, pseudoaneurysm thrombin injection, thoracentesis, and paracentesis.The infection prevention control (IPAC) committee at Mayo Clinic, Rochester, MN, conducts surveillance selected infections radiology procedures. When a positive culture, hospital admission, or operating room visit for is identified, patient's...
Patients with end-stage liver disease usually show a hyperdynamic circulatory state. It has previously been reported that patients who develop myocardial depression in the early post–liver transplantation period are more prone to organ failure and death. We reviewed records of 754 adult undergoing at our institution identified 7 initially showed circulation, but then developed reversible dilated cardiomyopathy posttransplantation period. All identifiable causes cardiac dysfunction, such as...
ObjectiveTo report the Mayo Clinic experience with coronavirus disease 2019 (COVID-19) related to patient outcomes.MethodsWe conducted a retrospective chart review of patients COVID-19 diagnosed between March 1, 2020, and July 31, at any sites. We abstracted pertinent comorbid conditions such as age, sex, body mass index, Charlson Comorbidity Index variables, treatments received. Factors associated hospitalization mortality were assessed in univariate multivariate models.ResultsA total 7891...
The protective efficacy of prior coronavirus disease 2019 (COVID-19) with or without vaccination remains unknown. This study sought to understand if 2 more messenger RNA (mRNA) vaccine doses provide additional protection in patients infection, infection alone provides comparable protection.We conducted a retrospective cohort the risk COVID-19 from 16 December 2020 through 15 March 2022, among vaccinated and unvaccinated all ages infection. A Simon-Makuch hazard plot illustrated incidence...