- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Thermal Regulation in Medicine
- Cardiac Arrest and Resuscitation
- Coronary Interventions and Diagnostics
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Heart Rate Variability and Autonomic Control
- Platelet Disorders and Treatments
- Cardiac tumors and thrombi
- Cardiac Imaging and Diagnostics
- Mechanical Circulatory Support Devices
- Peripheral Artery Disease Management
- ECG Monitoring and Analysis
- Blood Pressure and Hypertension Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Blood transfusion and management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
Mayo Clinic in Arizona
2021-2024
Jagiellonian University
2015-2024
Institute of Cardiology
2015-2024
Mayo Clinic
2021-2023
Leipzig Heart Institute
2022-2023
John Paul II Hospital
2013-2022
GTx (United States)
2020
Szpital Uniwersytecki w Krakowie
2019
Lodz University of Technology
2005-2016
Cleveland Clinic
2016
Abstract Background Accumulation of advanced glycation end products (AGEs) leads to chronic proteins and tissue damage, particularly in patients with diabetes mellitus (DM). We aimed evaluate whether increased accumulation AGEs aortic stenosis (AS) concomitant type 2 (DM) is associated AS severity. Methods prospectively enrolled 76 severe (47.1% males; nonDM), aged 68 [66–72] years, 50 age-matched DM a median blood glucose level 7.5 [5.9–9.1] mM glycated hemoglobin (HbA1c) 6.8 [6.3–7.8]%,...
Lung ultrasonography facilitates quick diagnosis at the bedside and is especially useful in emergency conditions. This video describes practical considerations for patients with most common causes of dyspnea.
Abstract Aims/hypothesis Type 2 diabetes has been demonstrated to predispose aortic valve calcification. We investigated whether type concomitant stenosis (AS) enhances valvular inflammation and coagulation activation via upregulated expression of NF-κB, with subsequent increased bone morphogenetic protein (BMP-2). Methods In this case–control study, 50 individuals severe isolated AS were compared a control group 100 without diabetes. The median (IQR) duration since diagnosis was 11 (7–18)...
Despite improvements in surgical management, sternal wound infection (SWI) following cardiac surgery remains a significant complication.To evaluate pathogens involved SWI median sternotomy.We enrolled 164 patients who experienced prolonged healing open-heart surgery. The inclusion criteria were as follows: via sternotomy and complete results of microbiological culture obtained from the swab. exclusion partial sternotomy, with mechanical sternum dehiscence incomplete clinical data. Swabs...
Atmospheric pressure is the most objective weather factor because regardless of if outdoors or indoors it affects all objects in same way. The majority previous studies have used average daily values atmospheric a bioclimatic analysis and found no correlation with blood changes. main our research was to assess relationship between recorded frequency 1 measurement per minute results 24-h monitoring patients treated hypertension different seasons moderate climate City Łódź (Poland).The study...
We sought to organize a functional system of recognition and advanced treatment hypothermic patients with extracorporeal rewarming as option. All suspected hypothermia are consulted the coordinator (HC), whose role is provide expertise on all rescue medical services. Patients Swiss staging class III IV subjected rewarming. I II managed in local hospitals, after HC provides instructions. From program initiation (July 29, 2013) November 1, 2015, 104 patients; 21 were John Paul Hospital Cracow,...
Background The management of severe mitral regurgitation (MR) after transcatheter edge-to-edge repair (TEER) remains a clinical conundrum. Considering the growing volume TEER, more outcomes data for surgery in this cohort are needed. Methods and Results Symptomatic patients with persistent or recurrent MR TEER evaluated between May 2014 June 2021 were included. primary outcome was all-cause mortality who treated versus medical therapy. Kaplan-Meier Cox regression methods used to report...
Pulmonary embolectomy is a treatment option in selected patients with high-risk pulmonary embolism (PE). Efficiency of thrombus degradation PE largely depends on the architecture its fibrin network, however little known about determinants. We present case 56-year-old woman and proximal deep-vein thrombosis, whose thrombotic material removed during from right atrium (lobar segmental) arteries has been studied using scanning electron microscopy (SEM). SEM images showed that distally located...
Background Minimally invasive mitral valve repair (MVr) is commonly performed. Data on the outcomes of robotic MVr versus nonrobotic minimally are lacking. We sought to compare short-term and mid-term MVr. Methods reviewed all patients who underwent (n = 424) or via right mini-thoracotomy 86) at Mayo Clinic, Rochester, MN, from January 2015 February 2020. baseline operative characteristics, long-term were analyzed. Patients matched 1:1 using propensity scores. Results Sixty-nine pairs...
Elevated asymmetric dimethylarginine (ADMA) is associated with an increased risk of coronary artery disease. A prognostic value ADMA following bypass grafting (CABG) unknown. The aim the current study was to assess effect CABG on and oxidative stress determine their associations postoperative complications.In 158 consecutive patients (35 women, 123 men, aged 65.2 ± standard deviation 8.2 years) undergoing isolated, elective procedure, we measured plasma 8-iso-prostaglandin F2α (8-iso-PGF2α)...
Abstract Background Left atrial appendage closure (LAAC) became an alternative method for stroke prevention in patients with non‐valvular fibrillation (AF) intolerant to long term oral anticoagulation therapy. This study aimed compare endocardial (Amulet and LAmbere occluders) epicardial (Lariat) LAAC techniques. Methods A retrospective, observational case‐control included 223 consecutive CHA 2 DS ‐VAS score–matched AF who underwent two centers. Results There were 55 matched cases the mean...
Routine coagulation tests and bleed-scores fail to identify patients at risk of excessive postoperative drainage following coronary artery bypass grafting (CABG). We sought investigate whether lower von Willebrand factor (VWF) higher ADAMTS13 (a disintegrin metalloproteinase with a thrombospondin type 1 motif, member 13) are associated high after CABG. In the prospective cohort study, VWF antigen (VWF:Ag), ristocetin cofactor (VWF:RCO), collagen-binding (VWF:CB), (ADAMTS13:Ag) activity were...
Background:Valve calcification is well estimated by ex-vivo micro-computed tomography (micro-CT). The objective of this study was to investigate the associations between micro-CT findings and biological indices in aortic stenosis (AS), as differences bicuspid valve (BAV) tricuspid (TAV).