Laia Castellà

ORCID: 0000-0003-2528-5359
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About
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Research Areas
  • Nosocomial Infections in ICU
  • Clostridium difficile and Clostridium perfringens research
  • Surgical site infection prevention
  • Helicobacter pylori-related gastroenterology studies
  • Microscopic Colitis
  • Antibiotic Resistance in Bacteria
  • Urinary Tract Infections Management
  • Hernia repair and management
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Antimicrobial Resistance in Staphylococcus
  • Anorectal Disease Treatments and Outcomes
  • Pelvic floor disorders treatments
  • Bacterial Identification and Susceptibility Testing
  • Antibiotic Use and Resistance

New York Proton Center
2024

Communities In Schools of Orange County
2024

University of Pittsburgh
2024

Lindsay Unified School District
2024

Oregon Medical Research Center
2024

Hospital Universitari Germans Trias i Pujol
2019-2023

Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2019-2023

Early detection of pathogen cross-transmission events and environmental reservoirs is needed to control derived nosocomial outbreaks. Whole-genome sequencing (WGS) considered the gold standard for outbreak confirmation, but, in most cases, it time-consuming has elevated costs. Consequently, timely incorporation WGS results conventional epidemiology (CE) investigations rapid scarce. Fourier transform infrared spectroscopy (FTIR) a technique that establishes similarity among bacteria based on...

10.3389/fmicb.2022.897161 article EN cc-by Frontiers in Microbiology 2022-06-09

Our aim was to determine changes in the incidence of CD infection (CDI) following introduction a two-step diagnostic algorithm and analyze CDI cases diagnosed study period. We retrospectively studied (January 2009 July 2018) adults by toxin enzyme immunoassay (EIA) (2009−2012) or toxin-EIA + polymerase chain reaction (PCR) (2013 onwards). A total 443 patients with first episode were included, 297 (67.1%) toxin-EIA-positive 146 (32.9%) toxin-EIA-negative/PCR-positive only identified through...

10.3390/microorganisms10051075 article EN cc-by Microorganisms 2022-05-23

Background Cancer has been associated with an increased risk of in-hospital mortality in CDI patients. However, data on delayed cancer patients are scarce. Aim/Objective The aim the present study was to compare outcomes between oncological and general population Clostridioides difficile infection (CDI) after 90 days follow-up. Methods A multicenter prospective cohort conducted 28 hospitals participating VINCat program. Cases were all consecutive adult who met case definition CDI....

10.1177/17571774231165410 article EN Journal of Infection Prevention 2023-03-21

Abstract We assessed hygiene with wet wipes in bedridden patients urinary catheters for catheter-associated tract infection (CAUTI) prevention. CAUTIs occurred 16.5% of the control group compared to 5.9% intervention ( P = .035). Hygiene can substitute conventional preventing CAUTI.

10.1017/ice.2023.178 article EN Infection Control and Hospital Epidemiology 2023-08-24

Background: The 2016 cumulative incidence of Clostridioides difficile infection (CDI) in Spain was reported by the European Center for Disease Control to be above mean other countries. aim this multicenter prospective observational cohort study examine risk factors that determine 90-day CDI recurrence Catalonia, Spain. Methods: included 558 consecutive adults admitted hospital who had a symptomatic, first positive diagnosis. Sociodemographic, clinical and epidemiological variables were...

10.2217/fmb-2022-0076 article EN Future Microbiology 2022-10-31

Background: Hospital-acquired Clostridioides difficile infection (HA-CDI) is a major control challenge. Using whole-genome sequencing, <40% of HA-CDI cases have been estimated to acquired from other inpatient cases. Huge regional variations described depending on the prevalence epidemic ribotypes. We hypothesized that, according geographical area, in rates between hospitals could be attributable either differences policies or antimicrobial consumption. Objectives: To assess association...

10.1017/ice.2020.1160 article EN Infection Control and Hospital Epidemiology 2020-10-01
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