A5016473727- Ophthalmology and Visual Impairment Studies
- Visual perception and processing mechanisms
- Tactile and Sensory Interactions
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Motor Control and Adaptation
- Ophthalmology and Eye Disorders
- Intraocular Surgery and Lenses
- Retinal Development and Disorders
- Ocular Disorders and Treatments
- Connexins and lens biology
- Neural dynamics and brain function
- Children's Physical and Motor Development
- Vestibular and auditory disorders
- Multisensory perception and integration
- Retinopathy of Prematurity Studies
- Advanced Optical Imaging Technologies
- Corneal surgery and disorders
- Face Recognition and Perception
- Cerebral Palsy and Movement Disorders
- Cognitive and developmental aspects of mathematical skills
- Retinal and Optic Conditions
- Hearing Loss and Rehabilitation
- Morphological variations and asymmetry
- Retinal Imaging and Analysis
Retina Foundation of the Southwest
2015-2025
University of Waterloo
2023-2025
The University of Texas Southwestern Medical Center
2016-2023
Southwestern Medical Center
2020-2023
York University
2010-2014
SickKids Foundation
2013
Hospital for Sick Children
2010-2013
University Health Network
2011
Canada Foundation for Innovation
2011
University of Toronto
2011
<h3>Importance</h3> Fellow eye patching has long been the standard treatment for amblyopia, but it does not always restore 20/20 vision or teach eyes to work together. Amblyopia can be treated with binocular games that rebalance contrast between so a child may overcome suppression. However, is unclear whether comparable in treating amblyopia. <h3>Objectives</h3> To assess effectiveness of iPad (Apple Inc) adventure game as amblyopia and compare this patching, current care. <h3>Design,...
Childhood amblyopia can be treated with binocular games or movies that rebalance contrast between the eyes, which is thought to reduce depth of interocular suppression so child experience vision. While visual acuity gains have been reported following treatment, studies rarely report in outcomes (i.e., stereoacuity, suppression) amblyopic children. Here, we evaluated children who had received treatment for childhood amblyopia.Data enrolled two ongoing were pooled. The sample included 41 (6...
<h3>Importance</h3> Reading and eye-hand coordination deficits in children with amblyopia may impede their ability to demonstrate knowledge skills, compete sports physical activities, interact peers. Because perceived scholastic, social, athletic competence are key determinants of self-esteem school-aged children, these influence a child's self-perception. <h3>Objective</h3> To determine whether is associated lowered self-perception competence, appearance, conduct, global self-worth the...
Suppression has a key role in the etiology of amblyopia, and contrast-balanced binocular treatment can overcome suppression improve visual acuity. Quantitative assessment could have managing amblyopia. We describe novel eye chart to assess children.We enrolled 100 children (7-12 years; 63 amblyopic, 25 nonamblyopic with strabismus or anisometropia, 12 controls) primary cohort 22 (3-6 13 9 nonamblyopic) secondary cohort. Letters were presented on dichoptic display (5 letters per line)....
<h3>Importance</h3> Deficits in fine motor skills and slow reading speed have been reported school-aged children adults with amblyopia. These deficits were correlated lower self-perception of athletic cognitive competence. Although perceived competence social acceptance are key determinants developing young children, the association amblyopia altered to date not for aged 3 7 years. <h3>Objectives</h3> To investigate whether is associated assess any differences vision skills. <h3>Design,...
Purpose: We evaluated motor skills in children diagnosed with strabismus and anisometropia, or without amblyopia, explored factors associated impairments. Methods: A total of 143 strabismic anisometropic 3 to 13 years age (96 amblyopic, 47 nonamblyopic) a group age-similar 35 control completed Manual Dexterity, Aiming Catching, Balance tasks from the Movement Assessment Battery for Children, Second Edition. Raw scores were converted standardized scores, amblyopic nonamblyopic compared...
Binocular treatment for unilateral amblyopia is an emerging that requires evaluation through a randomized clinical trial.This study aimed to compare change in amblyopic-eye visual acuity (VA) children aged 4 6 years treated with the dichoptic binocular iPad (Apple, Cupertino, CA) game, Dig Rush (not yet commercially available; Ubisoft, Montreal, Canada), plus continued spectacle correction versus alone.Children (mean age, 5.7 years) were randomly assigned home 8 weeks game (prescribed 1 h/d,...
Our objective was to measure how the misrouting of retinal ganglion cell (RGC) fibers affects organization optic chiasm and lateral geniculate nuclei (LGN) in human albinism. We compared chiasmal structures LGN both pigmented controls patients with albinism by using high-resolution structural magnetic resonance imaging (MRI). studied 12 oculocutaneous age-matched controls. Using a 3T MRI scanner, we acquired T1 -weighted three-dimensional magnetization-prepared rapid gradient-echo (MPRAGE)...
Retinoblastoma is a rare eye cancer that generally occurs before 5 years of age and often results in enucleation (surgical removal) the cancerous eye. In present study, we sought to determine consequences early monocular on morphological development anterior visual pathway including optic chiasm lateral geniculate nucleus.A group adults who had one enucleated life due retinoblastoma was compared binocularly intact controls. Although structural changes have previously been reported late...
SIGNIFICANCE We sought to identify baseline and clinical factors that were predictive of the response amblyopia treatment. report binocular treatment may be especially effective for moderate in orthotropic children. PURPOSE previously reported results from primary cohort (n = 28) enrolled a randomized trial (NCT02365090), which found was more than patching. Enrollment an additional 20 children pre-planned provide opportunity examine METHODS Forty-eight (4 10 years old) enrolled, with 24...
Stereotypical behaviors in captive polar bears (Ursus maritimus) can be detrimental to their welfare. These reduced through enrichment programs but are often not completely eliminated, so identifying potential triggers is important. The present study investigated the influences of seasonal changes, visitor density, and concurrent bear activity on stereotypical exhibited by 3 at Toronto Zoo. All these behaviors; however, individual differences were found duration form. male less behavior...
Abnormal binocular experience during infancy or childhood from strabismus and/or anisometropia results in visual acuity deficits (eg, amblyopia) and impaired stereoacuity. These pediatric eye conditions have also been linked to slow reading fine motor impairment.To assess an academic-related outcome-multiple-choice answer form completion time-in children with amblyopia strabismus.In this cross-sectional study completed between May 2014 November 2017 at a nonprofit research institute, 47...
Purpose: Binocular discordance due to strabismus, anisometropia, or both may result in not only monocular visual acuity deficits, but also motion perception deficits. We determined the prevalence of fellow-eye deficits motion-defined form (MDF) perception, ability identify a two-dimensional (2D) shape defined by rather than luminance contrast. examined following: causative role reduced and binocularity, associations with clinical sensory factors, effectiveness binocular amblyopia treatment...
We investigated the effects of early monocular enucleation (ME) (surgical removal one eye) on a high-level spatial visual ability, namely face perception. Early deprivation pattern vision from disorders such as strabismus, amblyopia, or cataract is associated with impairments in low-level vision. This inconsistent studies ME that show either equivalent enhanced compared controls. Impairments some aspects perception (i.e., feature-spacing and holistic processing, both which mature later life)...
Retinoblastoma is typically diagnosed before 5 years of age and often treated by enucleation (surgical removal) the cancerous eye. Here, we sought to characterize morphological changes cortex following long-term survival from early monocular enucleation.Nine adults with right-eye (≤48 months age) due retinoblastoma were compared 18 binocularly intact controls. Surface area, cortical thickness, gyrification estimates obtained T1 weighted images group differences examined.Early was associated...