- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Antibiotic Resistance in Bacteria
- Hepatitis Viruses Studies and Epidemiology
- Urinary Tract Infections Management
- Travel-related health issues
- Antibiotic Use and Resistance
- Cytomegalovirus and herpesvirus research
- Quality and Management Systems
- Animal Nutrition and Physiology
- Food Safety and Hygiene
- COVID-19 epidemiological studies
- Toxoplasma gondii Research Studies
- Gut microbiota and health
- Veterinary medicine and infectious diseases
- Bacterial Identification and Susceptibility Testing
- Listeria monocytogenes in Food Safety
- Pharmaceutical and Antibiotic Environmental Impacts
- Escherichia coli research studies
- Antibiotics Pharmacokinetics and Efficacy
- Fungal Infections and Studies
Utrecht University
2021-2024
National Institute for Public Health and the Environment
2020-2024
Universidad Nacional de la Amazonía Peruana
2023
National Research Institute for Veterinary Virology and Microbiology of Russia
2021-2022
University of Antwerp
2020
Salmonella remains a major cause of foodborne outbreaks in Europe despite the implementation harmonized control programmes. Outbreak data are observed at public health endpoint and provide picture most important sources human salmonellosis level exposure. To prioritize interventions, it is to keep abreast trends outbreaks. The objective this study was determine main food recent Europe. outbreak from 34 European countries 2015–2019 were obtained Food Safety Authority (EFSA). For source...
The public health measures implemented to control coronavirus disease 2019 (COVID-19) may influence also other infectious diseases. Using national laboratory surveillance data, we assessed the impact of COVID-19 pandemic on human salmonellosis in Netherlands until March 2021. Salmonellosis incidence decreased significantly after 2020: second, third and fourth quarters 2020, first quarter 2021, by 55%, 57%, 47% 37%, respectively, compared same 2016-2019. decrease was strongest among...
BackgroundSalmonellosis remains the second most common zoonosis in European Union despite a long-term decreasing trend. However, this trend has been reported to have stagnated recent years, particularly for
Antimicrobial use (AMU) in livestock contributes to antimicrobial resistance (AMR) among zoonotic pathogens, such as non-typhoid
After years of significant decline, the incidence Salmonella enterica serotype Enteritidis (SE) human infections in Europe has started stagnating recent years. The reasons for this stagnation remain largely unclear and are possibly multifactorial interconnected nature. We assessed ranked several potential determinants SE trend Europe, as well different options intervention at level poultry health production, public (infra)structure, pathogen biology.A Multi-Criteria Decision-Analysis (MCDA)...
Highlights Increased fluoroquinolone resistance in the two most common non-typhoidal Salmonella (NTS) serotypes among travellers returning to Netherlands.Resistant Enteritidis infections are likely be acquired abroad, specifically outside Europe.This study highlights importance of travel history when patients with NTS require empiric antimicrobial treatment.
To investigate whether prior exposure to non-fluoroquinolone antibiotics increases the risk of fluoroquinolone resistance in Escherichia coli.This was a secondary analysis data collected retrospectively case-control study linking microbiological test results (isolated bacteria and their susceptibility) urine samples routinely from primary, tertiary care patients Belgium with information on antibiotic use at patient level up 1 year previously.In 6125 patients, 7204 E. coli isolates were...
Abstract Background In the last decade, veterinary antimicrobial usage (AMU) and resistance (AMR) among indicator bacteria in livestock have decreased substantially Netherlands. The extent to which this decrease has affected AMR levels human infections remains unclear. Objectives To assess association between AMU Escherichia coli isolates from urinary tract (UTIs). Methods Data on 2009 2020 Dutch national surveillance programmes for humans were used. Associations four major sectors assessed...
Abstract Reducing antimicrobial use (AMU) in livestock may be one of the keys to limit emergence resistance (AMR) bacterial populations, including zoonotic pathogens. This study assessed temporal association between AMU and AMR among Campylobacter isolates from human infections Netherlands 2004 – 2020. Moreover, associations were assessed. data per class (tetracyclines, macrolides fluoroquinolones) for jejuni coli poultry, cattle, patients retrieved national surveillance programs....
Abstract Objectives To obtain comprehensive insight into the association of ciprofloxacin use at different times in past with current risk detecting resistance. Methods This retrospective nested case–control study users used Dutch data from PHARMO Database Network and one laboratory for period 2003–14. Cases controls were selected as patients an antibiotic susceptibility test (AST) indicating resistance or susceptibility, respectively. We performed univariable multivariable conditional...
Abstract Background Neurological opportunistic infections cause significant morbidity and mortality in people with human immunodeficiency virus (HIV) but are difficult to diagnose. Methods One hundred forty HIV acute neurological symptoms from Iquitos, Peru, were evaluated for cerebral toxoplasmosis quantitative polymerase chain reaction (qPCR) of cerebrospinal fluid (CSF) cryptococcal meningitis antigen test (CrAg) serum or CSF. Differences between groups assessed standard statistical...