Sofia M. Costa

ORCID: 0000-0003-2547-6470
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • biodegradable polymer synthesis and properties
  • Advanced Cellulose Research Studies
  • Nanocomposite Films for Food Packaging
  • Glycosylation and Glycoproteins Research
  • Monoclonal and Polyclonal Antibodies Research
  • Bacteriophages and microbial interactions
  • Protein purification and stability
  • Viral Infectious Diseases and Gene Expression in Insects
  • Additive Manufacturing and 3D Printing Technologies
  • Photodynamic Therapy Research Studies
  • Microbial Metabolites in Food Biotechnology
  • Nanoplatforms for cancer theranostics
  • Parasitic Infections and Diagnostics
  • Nanoparticles: synthesis and applications
  • Polysaccharides and Plant Cell Walls
  • Venomous Animal Envenomation and Studies
  • Enzyme Structure and Function
  • Escherichia coli research studies
  • Varied Academic Research Topics
  • Natural Fiber Reinforced Composites
  • Academic Research in Diverse Fields
  • Consumer Packaging Perceptions and Trends
  • Rabies epidemiology and control
  • Silk-based biomaterials and applications

University of Minho
2009-2024

Universidade do Porto
2018

National Institute of Health Dr. Ricardo Jorge
2014

Institute for Biotechnology and Bioengineering
2014

Abstract Cellulose has been intensively investigated for biomedical applications, because of its excellent properties, like biodegradability, biocompatibility, abundant availability renewable resources and cost-effectiveness. Among all sources cellulose, marine macroalgae or seaweeds, are acquiring tremendous attention, due to their high around the world. Moreover, atypical proliferation some exotic species represents a serious problem ecosystems, since accumulation threatens native oceanic...

10.1007/s10570-024-05816-w article EN cc-by Cellulose 2024-03-15

Cellulosic fibre-based smart materials exhibiting multiple capabilities are getting tremendous attention due to their wide application areas. In this work, multifunctional flax fabrics with piezoresistive response were developed through the combined functionalization silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs). Biodegradable polyethylene glycol (PEG) was used produce AgNPs, whereas ZnONPs synthetized via a simple low-cost method. Flax without NPs characterized by Ground State...

10.3390/nano8121069 article EN cc-by Nanomaterials 2018-12-19

Several studies have demonstrated that administration of doxorubicin (DOXO) results in cardiotoxicity, which eventually progresses to dilated cardiomyopathy. The present work aimed evaluate the early myocardial changes DOXO-induced cardiotoxicity. Male New Zealand White rabbits were injected intravenously with DOXO twice weekly for 8 wk [DOXO-induced heart failure (DOXO-HF)] or an equivolumetric dose saline (control). Echocardiographic evaluation was performed, and samples collected cellular...

10.1152/ajpheart.00401.2018 article EN AJP Heart and Circulatory Physiology 2018-12-07

Due to the prevalence of COVID-19 pandemic, demand for disposable facemasks has become a global issue. Unfortunately, use these products negative effects on environment, and therefore, biodegradable materials is powerful strategy overcome this challenge. Aligned with concept, in work, were developed using poly(ε-caprolactone) (PCL) polymer cotton natural fibers. The filter layer was produced an electrospinning technique, since electrospun membranes present remarkable characteristics air...

10.3390/app12010067 article EN cc-by Applied Sciences 2021-12-22

A thermoplastic starch (TPS) was produced, starting with potato starch, glycerol and acetic acid, to shape it in films of thickness around 100 microns. To TPS iron waste filing particles, the amount 12% weight were introduced different modalities: as received, reduced size by use a mortar, after treatment hydrochloric removal acid. Morphological studies carried out optical scanning electron microscopy illustrated that dispersion filings not optimal, though some improvement observed dimension...

10.28991/esj-2020-01218 article EN cc-by Emerging Science Journal 2020-06-01

Core–shell nanofibers loaded with porphyrin were produced to act as localized DDS for treating cervical cancer using PDT. Porphyrin-loaded electrospun showed a higher phototoxic effect against tumor cells compared non-tumor ones.

10.1039/d4ma00647j article EN cc-by-nc Materials Advances 2024-01-01

Multifunctional fibrous systems were developed within this research work, giving special importance to the electrical conductivity and antibacterial activity. The functionalization of several natural fibres (jute, sisal, coir, flax cotton) with silver nanoparticles (Ag NPs) was successfully achieved using a sustainable eco-friendly method, namely polyethylene glycol (PEG) reduction. FESEM images, GSDR ATR-FTIR analysis show that Ag NPs incorporated onto surface. resistivity values obtained...

10.4028/www.scientific.net/kem.812.66 article EN Key engineering materials 2019-07-01

In this work, natural-based and biodegradable nanofibers were produced by electrospinning for drug delivery wound dressing applications, using gelatin (Gel), chitosan (CS), cellulose nanocrystals (CNC) natural propolis extract. The polymeric formulations parameters optimized, resulting in the development of Gel/CS with mean diameters 97 nm. CNC successfully introduced into optimized solution viscosity conductivity values recorded. developed characterized FESEM, ATR-FTIR, TGA WCA....

10.4028/www.scientific.net/kem.893.45 article EN Key engineering materials 2021-07-20
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