A5029843913- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Healthcare Policy and Management
- Pharmaceutical industry and healthcare
- Opioid Use Disorder Treatment
- Medication Adherence and Compliance
- Pharmaceutical studies and practices
- Diabetes Management and Education
- Adolescent and Pediatric Healthcare
- COVID-19 epidemiological studies
- Primary Care and Health Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Vaccine Coverage and Hesitancy
- Mobile Health and mHealth Applications
- Chronic Disease Management Strategies
- Economic and Financial Impacts of Cancer
- Geriatric Care and Nursing Homes
- Health disparities and outcomes
- Musculoskeletal pain and rehabilitation
- Biosimilars and Bioanalytical Methods
- Neurogenetic and Muscular Disorders Research
- Eosinophilic Esophagitis
- Healthcare cost, quality, practices
- CRISPR and Genetic Engineering
- Artificial Intelligence in Healthcare
Johns Hopkins University
2016-2025
American Society of Safety Professionals
2023
Boston University
2022
University of Georgia
2022
Harvard University
2022
Postnova Analytics (United States)
2019-2021
University of Maryland, Baltimore
2014
Despite epidemic rates of addiction and death from prescription opioids in the United States, suggesting importance providing alternatives to treatment pain, little is known regarding how payers' coverage policies may facilitate or impede access such treatments.To examine for 5 nonpharmacologic approaches commonly used treat acute chronic low back pain among commercial Medicare Advantage insurance plans, plus an additional 6 treatments Medicaid plans.Cross-sectional study 15 commercial,...
The Novel Coronavirus (COVID-19) has infected over two hundred million worldwide and caused 4.4 of deaths as August 2021. Vaccines were quickly developed to address the pandemic. We sought analyze cost-effectiveness budget impact a non-specified vaccine for COVID-19.We constructed Markov model COVID-19 infections using susceptible-exposed-infected-recovered structure 1-year time horizon from U.S. healthcare sector perspective. consisted arms: do nothing vaccine. Hospitalization mortality...
<h3>Importance</h3> Prior research suggests an association between burden of disease and National Institutes Health (NIH) funding. The allocation NIH funding should reflect, to some extent, the health needs population, along with other factors. <h3>Objective</h3> To examine factors associated in 2019 for 46 diseases. <h3>Design, Setting, Participants</h3> This cohort study used disability-adjusted life-years measure 2008 US compared them categoric <h3>Exposures</h3> Disability-adjusted...
The U.S. has the tools to end HIV epidemic, but progress stagnated. A major gap in efforts address is under-utilization of medications that can virtually eliminate acquisition virus, known as pre-exposure prophylaxis (PrEP). This document proposes a financing and delivery system unlock broad access PrEP for those most vulnerable bring an epidemic.
<h3>Importance</h3> Despite unprecedented injuries and deaths from prescription opioids, little is known regarding medication coverage policies for the treatment of chronic noncancer pain among US insurers. <h3>Objective</h3> To assess 62 products used to treat low back pain. <h3>Design, Setting, Participants</h3> A cross-sectional study health plan documents 15 Medicaid, Medicare Advantage, 20 commercial plans in 2017 16 states representing more than half population interviews with 43...
<h3>Importance</h3> The US opioid epidemic is complex and dynamic, yet relatively little known regarding its likely future impact the potential mitigating of interventions to address it. <h3>Objective</h3> To estimate burden burden. <h3>Design, Setting, Participants</h3> A decision analytic dynamic Markov model was calibrated using 2010-2018 data from National Survey on Drug Use Health, Centers for Disease Control Prevention, Health Nutrition Examination Survey, Census, Epidemiologic Alcohol...
Chronic rhinosinusitis with nasal polyposis (CRSwNP) in the setting of aspirin-exacerbated respiratory disease (AERD) is a that difficult to treat and prone recurrence. Dupilumab promising treatment for these patients, but its cost-effectiveness has not yet been compared aspirin (acetylsalicyclic acid, or ASA) desensitization, known effective treatment. We aimed compare ASA desensitization dupilumab therapy CRSwNP AERD.Analyses cost-effectiveness, as measured quality-adjusted life years...
School-based programmes, including hearing screening, provide essential preventive services for rural children. However, minimal evidence on screening methodologies, loss to follow-up, and scarcity of specialists subsequent care compound health disparities. We hypothesised telemedicine specialty referral would improve time follow-up school compared with standard primary referral.In this cluster-randomised controlled trial conducted in 15 Alaskan communities, USA, we randomised communities...
In a survey of adults in 11 high-income countries, the United States ranks last on measures financial access to care as well availability nights and weekends. Uninsured Americans are particularly likely report encountering barriers care.
ABSTRACT Background Pelvic inflammatory Disease (PID) disproportionately impacts adolescents and young adult women. The Technology-Enhanced Community Health Nursing (TECH-N) trial demonstrated the potential benefit of a novel community health intervention for with PID. We assess cost-effectiveness TECH-N compared to standard care. Methods constructed cohort Markov model PID in an urban setting. used nine states: PID, two states STIs, four sequelae, recovery deceased states. consisted...
The inflationary rebate provisions of the Inflation Reduction Act (IRA) 2022 require pharmaceutical manufacturers to pay money back Medicare if they raise prices faster than rate inflation. Opportunities now exist for Congress and states extend rebates commercial plans. We demonstrate potential savings from applying prescriptions filled in plans by simulating under several policy design options. estimate that a mimicking IRA's could have saved as much $8.1 billion 2021 imposing on 1,100...
Importance Allowing the US Centers for Medicare &amp;amp; Medicaid Services to negotiate prescription drug prices may improve affordability. Objective To estimate savings from price negotiation under Inflation Reduction Act (IRA) and examine opportunities increase savings. Design, Setting, Participants This cross-sectional, population-based study used data 2020 claims. The was conducted were analyzed in 2022. Exposures Eligibility IRA alternative criteria. Main Outcomes Measures Minimum...
Health care reform efforts that emphasize value have increased awareness of the importance nonmedical factors in achieving better care, health, and lower costs high-need, high-cost individuals. Programs for socioeconomically disadvantaged, individuals achieved promising results part by bridging traditional service delivery silos. This study examined 5 innovative community-oriented programs are successfully coordinating medical services to identify stimulate sustain community-level...
The U.S. Food and Drug Administration provides accelerated approval to drugs on the basis of surrogate end points deemed be "reasonably likely" predict clinical benefit. To receive full approval, must complete a confirmatory trial. Although most approved ultimately others remain market without for many years, some are withdrawn before is granted. Until trials completed granted, there uncertainty surrounding each drug's benefits.To estimate fee-for-service Medicare payments...
To determine the relative profitability for a hospital of treatment common fractures within state-regulated reimbursement system.Retrospective cohort.Regional trauma referral center with system.We reviewed medical and financial records 1228 patients admitted from 2008 through 2012 principle diagnosis acute traumatic fracture requiring surgical treatment. Patients whose fit into 1 6 anatomic categories were included. Sixty-five pelvic, 275 acetabular, 277 hip, 255 femoral shaft, 148 tibial...
Gene and RNA therapies are promising treatments for many rare diseases. Pediatric populations that could benefit from these drugs overrepresented among state Medicaid programs. Using State Drug Utilization Data, we examined spending utilization of disease gene therapies. Between 2017 2022, the number available increased 3 to 13, yearly $148.3 million $879.7 million, (a proxy patients) 327 1638. Nearly all was attributed spinal muscular atrophy (SMA) Duchenne dystrophy drugs. States...
Prediabetes is a highly prevalent condition that heralds an increased risk of progression to type 2 diabetes, along with associated microvascular and macrovascular complications. The Diabetes Prevention Program (DPP) established effective intervention for diabetes prevention. However, participation in this 12-month lifestyle change program has historically been low. Digital DPPs have emerged as scalable alternative, accessible asynchronously recognized by the Centers Disease Control (CDC)....
Abstract Background and aims Despite prescribing declines between 2011 2019, opioid morbidity mortality in the United States continued to rise during this period. We estimated relationship prescribing, use disorder (OUD) fatal overdose States. Design Dynamic Markov model. Setting States, using data from National Survey on Drug Use Health, Centers for Disease Control Prevention, Health Nutrition Examination Epidemiologic Alcohol Related Conditions III. Participants Simulated US individuals...
To assess the cost-effectiveness of a digital diabetes prevention programme (d-DPP) compared with (DPP) for preventing type 2 (T2D) in individuals prediabetes United States.