- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Colorectal Cancer Treatments and Studies
- Melanoma and MAPK Pathways
- Cutaneous Melanoma Detection and Management
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Cervical Cancer and HPV Research
- Brain Metastases and Treatment
- Endometrial and Cervical Cancer Treatments
- PI3K/AKT/mTOR signaling in cancer
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Surgical Treatments
- Head and Neck Cancer Studies
- RNA regulation and disease
- Protein Kinase Regulation and GTPase Signaling
- Autoimmune Neurological Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Mechanisms of cancer metastasis
- Cancer Diagnosis and Treatment
- CAR-T cell therapy research
- Cancer Mechanisms and Therapy
German Cancer Research Center
2023-2025
Heidelberg University
2023-2025
All India Institute of Medical Sciences
2019-2023
Maulana Azad Medical College
2018
University of Delhi
2018
Background Immune checkpoint inhibitors (ICIs) are the gold standard therapy in patients with deficient mismatch repair (dMMR)/microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC). A significant proportion of show resistance, making identification determinants response crucial. Growing evidence supports role sex determining susceptibility to anticancer therapies, but data is lacking for MSI-H CRC. Methods In this real-world cohort comprising 624 mCRC receiving ICIs, we...
Abstract Background This study aims to analyze risk factors, clinical profiles, treatment protocols, and disease outcomes in histologically proven resectable vulvar cancer (VC) patients according tumor stage. is a retrospective analysis of prospectively collected database 20 VC from May 2014 June 2019. Results The mean age diagnosis was 55 years, with range 38–84 years. incidence four cases per year. significantly more post-menopausal (65%) multiparous (90%) women. According FIGO staging...
Background: Carcinoma ovary is very rarely associated with paraneoplastic cerebellar degeneration (PCD). The first clinical manifestations of primary malignancy could be symptoms. presence specific serum onconeural antibodies (Abs) in ataxia patients may guide clinicians to search for the tumor by different investigation modalities. Case: A 71-year female presented symptoms gait and urinary incontinence. There were high levels anti-Yo Ab rapid progression no known etiology, which led...
Abstract Introduction The AJCC eighth edition TNM classification for lung cancer was released in 2017 and included major newer modifications. External validation studies have evaluated the efficacy of new system obtained paradoxical results. Methods A meta-analysis performed these to evaluate classification. Eight eligible with 654,185 patients were analysis. Hazard ratios (HRs) associated 95% confidence intervals extracted from identified studies. primary outcomes survival discrimination...