Mykhailo Nahorniak

ORCID: 0000-0003-2586-9741
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Research Areas
  • Luminescence Properties of Advanced Materials
  • Nanoparticle-Based Drug Delivery
  • Nanoplatforms for cancer theranostics
  • Advanced Photocatalysis Techniques
  • Hydrogels: synthesis, properties, applications
  • Luminescence and Fluorescent Materials
  • biodegradable polymer synthesis and properties
  • Human Health and Disease
  • Advanced Theoretical and Applied Studies in Material Sciences and Geometry
  • Photodynamic Therapy Research Studies
  • Scientific Research and Studies
  • Inhalation and Respiratory Drug Delivery
  • Advanced biosensing and bioanalysis techniques
  • GaN-based semiconductor devices and materials
  • Lanthanide and Transition Metal Complexes
  • Characterization and Applications of Magnetic Nanoparticles
  • Iron oxide chemistry and applications
  • Biopolymer Synthesis and Applications
  • Biosensors and Analytical Detection

Czech Academy of Sciences, Institute of Macromolecular Chemistry
2022-2023

Lviv Polytechnic National University
2023

Upconverting nanoparticles (UCNPs) are of particular interest in nanomedicine for vivo deep-tissue optical cancer bioimaging due to their efficient cellular uptake dependent on polymer coating. In this study, particles, ca. 25 nm diameter, were prepared by a high-temperature coprecipitation lanthanide chlorides. To ensure optimal dispersion UCNPs aqueous milieu, they coated with three different polymers containing reactive groups, i.e., poly(ethylene glycol)-alendronate (PEG-Ale),...

10.3390/ijms24032724 article EN International Journal of Molecular Sciences 2023-02-01

High-quality upconverting NaYF4:Yb3+,Er3+ nanoparticles (UCNPs; 26 nm in diameter) based on lanthanides were synthesized by a high-temperature coprecipitation method. The particles modified bisphosphonate-terminated poly(ethylene glycol) (PEG) and Rose Bengal (RB) photosensitizer. thoroughly characterized using transmission electron microscopy, dynamic light scattering, thermogravimetric analysis, FTIR, X-ray photoelectron upconversion luminescence spectroscopy terms of morphology,...

10.3390/life12091383 article EN cc-by Life 2022-09-05

Large (120 nm) hexagonal NaYF 4 :Yb, Er nanoparticles (UCNPs) were synthesized by high-temperature coprecipitation method and coated with poly(ethylene glycol)-alendronate (PEG-Ale), poly ( N , -dimethylacrylamide- co -2-aminoethylacrylamide)-alendronate (PDMA-Ale) or poly(methyl vinyl ether- -maleic acid) (PMVEMA). The colloidal stability of polymer-coated UCNPs in water, PBS DMEM medium was investigated dynamic light scattering; UCNP@PMVEMA particles showed the best PBS. Dissolution PBS,...

10.3389/fchem.2023.1207984 article EN cc-by Frontiers in Chemistry 2023-06-23

Different iron oxides (i.e., magnetite, maghemite, goethite, wüstite), particularly nanosized particles, show distinct effects on living organisms. Thus, it is of primary importance for their biomedical applications that the morphology and phase-structural state these materials are investigated. The aim this work was to obtain magnetic nanoparticles in a single reactor using Fe(III) acetylacetonate as initial precursor synthesis oleate or undecylate followed by thermolysis situ. We proposed...

10.3762/bjnano.14.2 article EN cc-by Beilstein Journal of Nanotechnology 2023-01-03

In this report, we synthesized hexagonal NaYF4:Yb,Er upconverting nanoparticles (UCNPs) of 171 nm in size with a narrow particle distribution. To address their colloidal stabi-lity aqueous media and to incorporate photosensitizer that can produce reactive singlet oxygen (1O2) kill tumor cells, UCNPs were conjugated 6-bromohexanoic acid-functionalized Rose Bengal (RB) coated PEG-alendronate (PEG-Ale). The particles thoroughly characterized by transmission electron microscopy, dynamic light...

10.3390/nano13091535 article EN cc-by Nanomaterials 2023-05-03

Different iron oxides (i.e., magnetite, maghemite, goethite, wüstite) show distinct effects on biological objects, and thus the investigations of morphology phase-structural state have prime priority for their biomedical applications. The aim this work was to develop one-pot synthesis magnetic nanoparticles by thermolysis Fe(III)-oleate or Fe(III)-undecylate in a high-boiling point solvent situ , using Fe(III)-acetylacetonate. Magnetic were characterized transmission electron microscopy,...

10.3762/bxiv.2022.12.v1 preprint EN 2022-03-02

The content of total protein and its spectrum in the blood were studied when rats fed metal complexes (ME; Fe+2/+3-, Zn+2-, Cu+2 - Mn+2-) as part a polymer transporter (MEmLPEG400) diet deficient nutrients.
 It was found that complete diet, plasma is 107.5±3.0 g/l 15.6 17.8% higher experimental groups. At same time, animals groups, γ-globulins 2.3 2.9 times (р < 0.05 0.001) than while albumin, on contrary, reduced. β-globulins maximum (18.6±1.42%) control 6.8 11.6% (p lower wheat...

10.36359/scivp.2023-24-2.05 article EN Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology 2023-11-30

Розглянуто проблеми введення наночастинок магнетиту в гідрогелеві дисперсії, які створені на основі поліакриламіду.Утворення полімерного каркаса гідрогелю відбувалось за рахунок збалансованої кількості поперечних зшивок між поліакриламідом та полі-Nгідроксиметилакриламідом.Вивчено структурування поліакриламіду полі-N-(гідроксиметил)акриламіду присутності солей феруму -прекурсорів показано вплив добавок параметри тривимірної сітки гідрогелю.Проведено оптимізацію складу вивчення стабільності...

10.23939/ctas2019.02.159 article UK Chemistry Technology and Application of Substances 2019-11-01
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