A5017864858- Botulinum Toxin and Related Neurological Disorders
- Diphtheria, Corynebacterium, and Tetanus
- Streptococcal Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Antimicrobial Resistance in Staphylococcus
- Microscopic Colitis
- Biochemical and Structural Characterization
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Trace Elements in Health
- Infections and bacterial resistance
- Tuberculosis Research and Epidemiology
- Hereditary Neurological Disorders
- Nerve injury and regeneration
- Escherichia coli research studies
- Immune Response and Inflammation
- Aquaculture disease management and microbiota
- Infectious Disease Case Reports and Treatments
Istituto Zooprofilattico Sperimentale delle Venezie
2013-2025
Background/Objectives. Bovine botulism, although relatively rare, presents significant economic losses due to high mortality rates and restrictions on livestock product trade. Vaccination remains the most effective strategy for preventing botulism-related mortality. This study evaluated efficacy of a bivalent recombinant vaccine targeting C-terminal portion heavy chain (Hc) botulinum neurotoxin serotype C (BoNT/C) (Hc BoNT/C) D (BoNT/D) BoNT/D) in inducing neutralizing antibodies against...
In animals, botulism is commonly sustained by botulinum neurotoxin C, D or their mosaic variants, which are produced anaerobic bacteria included in Clostridium group III. this study, a WGS has been applied to large collection of C. III field strains order expand the knowledge on these BoNT-producing Clostridia and evaluate potentiality method for epidemiological investigations. Sixty were submitted WGS, results analyzed with respect information compared published sequences. The isolated from...
The present study describes the isolation of Methicillin-resistant Staphylococcus aureus (MRSA) from respiratory tract 2 dolphins different origin, a stranded juvenile Risso's dolphin (Grampus griseus) and captive born common bottlenose (Tursiops truncatus) calf, which died in same institution at 1-month distance other. A complete microbiological genetic investigation confirmed presence MRSA clone-complex 8, sequence type (ST) spa-type t008 both individuals. This strain differs one...
Botulinum neurotoxins (BoNTs) are among the most poisonous known biological substances, and therefore availability of reliable, easy-to use tools for BoNT detection important goals food safety human animal health. The reference method toxin identification is mouse bioassay (MBA). An EndoPep-MS differentiation has been developed based on mass spectrometry. We have validated implemented a Bruker MALDI Biotyper BoNT/C D serotypes. was extensively using experimentally naturally contaminated...
The presence of botulinum neurotoxin-producing Clostridia (BPC) in food sources is a public health concern. In favorable environmental conditions, BPC can produce neurotoxins (BoNTs) outside or inside the vertebrate host, leading to intoxications toxico-infectious forms botulism, respectively. are almost invariably detected either by PCR protocols targeted at known neurotoxin-encoding genes, mouse test assay for BoNTs supernatants enrichment broths inoculated with tested sample. sample...
The present report describes two outbreaks of serious enteritis in commercial laying hens where Clostridium perfringens and colinum were simultaneously detected. At the age 44 31 weeks, hen flocks showed an increase mortality rate a worsening productive performance. Post-mortem examination revealed intestinal necrotic-haemorrhagic ulcerations hepatic focal necrosis. bacteriological yielded isolation C. toxin type A, NetB positive. In one outbreak, was detected also by polymerase chain...