Khaled S. Nassar

ORCID: 0000-0003-2597-4170
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Research Areas
  • Proteins in Food Systems
  • Meat and Animal Product Quality
  • Probiotics and Fermented Foods
  • Microbial Inactivation Methods
  • Microencapsulation and Drying Processes
  • Cancer Research and Treatments
  • Gut microbiota and health
  • Polysaccharides Composition and Applications
  • Freezing and Crystallization Processes
  • Animal Diversity and Health Studies
  • Essential Oils and Antimicrobial Activity
  • Digestive system and related health
  • Phytochemicals and Antioxidant Activities
  • Phytochemical and Pharmacological Studies
  • Glycosylation and Glycoproteins Research
  • Phytochemistry and Biological Activities
  • Cancer Mechanisms and Therapy
  • Food Industry and Aquatic Biology
  • Phytase and its Applications
  • Medicinal Plants and Neuroprotection
  • Microbial Metabolites in Food Biotechnology
  • Natural Antidiabetic Agents Studies
  • Peptidase Inhibition and Analysis

Damanhour University
2019-2025

Institute of Food Science and Technology
2019-2024

Chinese Academy of Agricultural Sciences
2019-2024

The gut microbiota plays important roles in chronic inflammation and colon cancer. Lactobacillus is a gut-resident probiotic with benefits to host health. We recently identified plantarum strain YYC-3 strong inhibition against two cancer cell lines (HT-29 Caco2). However, the inhibitory effect of vivo has not been verified. Thus, present study, we explored function its cell-free supernatant (YYCS) respectively APCMin/+ mouse model during tumour development growth, underlying anti-cancer...

10.1016/j.biopha.2020.110159 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2020-04-27

Abstract Background Colorectal cancer (CRC) is a major clinical challenge, and the gut microbiome plays important roles in occurrence metastasis of CRC. Lactobacillus their metabolites are thought to be able suppress growth CRC cells. However, antimetastatic mechanism or toward cells not clear. Therefore, aim this study was assess inhibitory cell-free supernatants (CFSs) L. rhamnosus GG, casei M3, plantarum YYC-3 on Results CFS showed highest effect cell growth, invasion migration, inhibited...

10.1186/s12934-020-01466-2 article EN cc-by Microbial Cell Factories 2020-11-23

The effect of high-intensity thermosonication (HIT) pretreatment (20 kHz frequency, output power 4000 W and 25% amplitude for 5, 10 15 min) on the physicochemical rheological properties stirred yoghurt made from goat milk was studied. Various parameters were evaluated, such as particle size, pH soluble calcium phosphorus, while other evaluated during storage (up to 18 days), measurements, syneresis, values, titratable acidity, color, sensory properties. microstructure had more interconnected...

10.3390/fermentation9010042 article EN cc-by Fermentation 2023-01-03

The antibacterial efficacy of clove extracts (Syzygium aromaticum) prepared using 80% ethanol and water against pathogenic bacteria was evaluated, along with the development a novel antimicrobial milk beverage incorporating these extracts. Seven flavored (FMB) treatments were prepared: control 6 at 0.5%, 0.7%, 1% for each solvent. effects on physicochemical, phytochemical, antioxidant, microbiological, color, sensory properties assessed over 15 d storage 4 ± 1°C. ethanolic extract exhibited...

10.3168/jds.2024-26023 article EN cc-by Journal of Dairy Science 2025-02-01

The gut microbiota plays an important role in intestinal health. Probiotics such as Lactobacillus are known to regulate microbes and prevent diseases. However, most of them unable colonize their stability hosts' tracts. In this study, we investigated the ability casei SY13 (SY13) tract BALB/c mice, after its oral administration for a short-term (once day) long-term daily 27 days) duration. Furthermore, also evaluated influence on microbial structure diversity mice. Male mice were gavaged...

10.1155/2020/5281639 article EN cc-by BioMed Research International 2020-02-13

Verbena officinalis L. is a traditionally important medicinal herb that has rich source of bioactive phytoconstituents with biological benefits. The objective this study was to assess the metabolic profile and in vitro potential V. officinalis. were evaluated by preliminary phytochemical studies, estimation polyphenolic contents, gas chromatography-mass spectrometry (GC-MS) analysis all fractions (crude methanolic, n-hexane, ethyl acetate, n-butanol) investigation performed different assays...

10.3390/molecules27196685 article EN cc-by Molecules 2022-10-08

The objective of this study was to evaluate the nutritional value dried Kishk-like products using burghal wheat, oat, and fenugreek with cow’s milk, camel’s goat’s milk. Kishk is an artisanal product that popular in Egypt Middle East. This made primarily wheat; however, our knowledge, no research has used seeds making it. Changes physicochemical, microbial, sensory properties samples were followed over 90 days storage at room temperature. proximate analysis fenugreek–Kishk (CF, AF, GF)...

10.3390/fermentation9100919 article EN cc-by Fermentation 2023-10-20

Thermosonication (TS) prior to conventionally heated (95 o C for 10 min) goat milk (GM) (at an ultrasound frequency of 20 kHz and output power 4000 W, from 5 15 effected the preparation yoghurts with microstructure texture properties superior those control yoghurt samples produced homogenization (HM) before at same temperature.Thermosonication altered secondary structure protein which decreased β-sheet content increased amount α-helix leading increase hydrophobicity.As well as in...

10.21608/asejaiqjsae.2021.211545 article EN cc-by-nc-sa Alexandria Science Exchange Journal 2021-12-30

The present investigation was conducted to study the effect of partial substitution UF-retentate skimmed cow's milk with denatured salt whey protein past (DSWPP) aiming obtain optimal formulation two ingredients for manufacturing feta cheese analogue. In this study, ratios were 5, 10, 15 and 20% (wt/wt). Physicochemical properties, texture profile, organoleptic microbial quality economic efficiency UF-FCA studied along 60 days refrigeration storage (6±2°C). Inclusion DSWPP caused significant...

10.21608/asejaiqjsae.2024.343050 article EN Alexandria Science Exchange Journal 2024-03-09
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