- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Natural Antidiabetic Agents Studies
- Natural product bioactivities and synthesis
- Edible Oils Quality and Analysis
- Plant biochemistry and biosynthesis
- Genomics, phytochemicals, and oxidative stress
- Medicinal Plants and Neuroprotection
- Advanced Glycation End Products research
- Phytochemistry and biological activities of Ficus species
- Free Radicals and Antioxidants
- Hibiscus Plant Research Studies
- Fermentation and Sensory Analysis
- Bee Products Chemical Analysis
- Botanical Studies and Applications
- Phytochemistry and Bioactivity Studies
- Insect Pest Control Strategies
- Flavonoids in Medical Research
- Algal biology and biofuel production
- Aquatic Ecosystems and Phytoplankton Dynamics
- Medicinal Plant Extracts Effects
- Plant chemical constituents analysis
- Antifungal resistance and susceptibility
- Psidium guajava Extracts and Applications
University of Messina
2019-2024
Université Moulay Ismail de Meknes
2019-2021
This study aimed to investigate the potential of four sea water microalgae, isolated and cultivated at M'diq Bay in Morocco, as a new source natural antioxidants. These microalgae belong different classes, including Phaedactylium tricornitum (Bacillariophyceae), Nannochloropsis gaditana (Eustigmatophyceae), Nannochloris sp (Trebouxiophyceae), Tetraselmis suecica (Chlorodendrophycea). The antioxidant properties were screened by use vitro assays, namely 2,2-difenil-1-picrylhydrazyl, Ferric...
Diabetes and its complications are closely correlated with chronic hyperglycemia, causing severe oxidative stress leading to glycation reaction formation of advanced end products. However, medicinal plants still a source inspiration for the discovery new treatments several diseases, including diabetes. The present study was aimed evaluate antioxidant antidiabetic properties Oxalis pes-caprae flowers extract in alloxan-induced diabetic mice. phytochemical activities both aqueous methanolic...
The Moroccan flora is rich in medicinal plants that are commonly used folk medicine for the treatment of various diseases. present study was designed to investigate total phenolic and flavonoid contents, as well antioxidant properties leaves extracts from Globularia alypum L. colected Taza region northeast Morocco. Additionally, individual phenolics volatiles were also evaluated. organic this plant obtained by Soxhlet extraction using two different solvents, namely ethyl acetate chloroform....
Essential oils were proposed as natural additives to ensure food safety and quality in a more sustainable approach. The chemical composition of Thymus vulgaris essential oil (TV-EO) collected from Morocco, its antioxidant antimicrobial activity against different serotypes Salmonella enterica subsp. was investigated. A mathematical model implemented predict the behavior when exposed TV-EO. In situ sensory influence tested minced poultry meat experimentally contaminated with treated...
Medicinal plants offer imperative sources of innovative chemical substances with important potential therapeutic effects. Among them, the members genus Inula have been widely used in traditional medicine for treatment several diseases. The present study investigated antioxidant (DPPH, ABTS and FRAP assays) vitro anti-hyperglycemic aerial parts viscosa (L.) Aiton (I. viscosa) extracts through inhibition digestive enzymes (α-amylase α-glucosidase), responsible digestion poly oligosaccharides....
Thymus zygis subsp. gracilis, Mentha suaveolens and Sideritis incana (Lamiaceae family) are well recognized for their medicinal, pharmaceutical aromatic properties. The present study aimed to investigate the first time phenolic composition, antioxidant antibacterial properties of extracts obtained from aerial parts these species collected Ifrane region Morocco. compounds were determined using high-performance liquid chromatography coupled photodiode array electrospray ionization mass...
This work focused on the leaves of Dittrichia viscosa, a plant used in Mediterranean folk medicine. Compared to water extract, methanolic extract had higher antioxidant effects. Moreover, this showed potent vitro inhibitory activity against α-amylase and α-glucosidase an interesting antiglycation effect. Additionally, evaluation cytotoxic two human breast cancer cell lines, MCF-7 MDA-MB-468, was very promising, with no cytotoxicity towards normal cells (peripheral blood mononuclear (PBMCs)....
Rosa damascena is referred to as the queen of roses due its ornamental, flavoring, and perfuming uses, along with recognized use in therapy. This study aimed investigate total phenols flavonoids contents, phenolic compounds, antioxidant antibacterial properties hydroethanolic extract from flowers, collected Middle Atlas Morocco (Khenifra). The were assessed using gallic acid quercetin standards, compounds characterized HPLC-PDA-ESI/MS. activity was evaluated by two methods, namely ferric...
Saffron petals, which are the main by-products of Crocus sativus L. (Iridaceae family), produced in large quantities and known for their many beneficial properties. In this regard, study aims to investigate phenolic composition antibacterial properties hydroethanolic extracts from petals collected Serghina (province Boulmane) Morocco. The profiles were characterized using high-performance liquid chromatography coupled a photodiode array electrospray ionization mass spectrometry...
Medicinal plants are considered a major source for discovering novel effective drugs. To our knowledge, no studies have reported the chemical composition and biological activities of Moroccan Lactuca saligna extracts. In this context, study aims to characterize polyphenolic compounds distributed in hydro-methanolic extracts L. evaluate their antioxidant antibacterial activities; addition, silico analysis based on molecular docking ADMET was performed predict activity identified phenolic...
Wild jujube “Ziziphus lotus (L.) Desf.” belongs to the Rhamnaceae family and is a traditionally herbaceous medicinal plant. It very common in arid semi-arid regions currently used for its antidiabetic, sedative, analgesic, anti-inflammatory hypoglycemic activities. The aim of present work was characterize physico-chemical properties phytochemical profile wild sample collected from Guercif region, order determine polyphenolic compounds antioxidant ability Analyses were carried out directly...
The composition of polyphenols, chlorophylls and carotenoids eight extracts Convolvulus althaeoides L. leaves, harvested in two different seasons, winter spring, extracted by hot extraction method using four solvents (dichloromethane, chloroform, ethyl acetate ethanol) with increasing polarity, were evaluated along their antioxidant antifungal activities. Qualitative quantitative variations observed the based on high performance liquid chromatography systems, chromatography-photodiode array...
The aim of this study was to determine the polyphenolic compounds and antioxidant ability Arbutus unedo fruits, collected from three regions northern Morocco, using high-performance liquid chromatography coupled diode array electrospray ionization mass spectrometry detection. proper extraction method has been selected achieve objective. After delipidation, harvests were extracted by sonication two solvents with increased polarity ethyl acetate MeOH:water, 80:20 (v/v). Total polyphenols,...
The aim of this study was to characterize the phytochemical content as well antioxidant ability Moroccan species Chamaerops humilis L. Besides crude ethanolic extract, two extracts obtained by sonication using solvents with increased polarity, namely ethyl acetate (EtOAc) and methanol-water (MeOH-H2O) 80:20 (v/v), were investigated both spectroscopy chromatography methods. Between extracts, MeOH-H2O one showed highest total polyphenolic equal 32.7 ± 0.1 mg GAE/g DM respect EtOAc extract (3.6...
Hibiscus sabdariffa L. (H.s.) is a polyphenolic-rich plant commonly consumed either as beverage or spice. The aim of the present study was to evaluate in vitro digestibility H.s. polyphenols using an model digestion which simulates human stomach and small intestine. bioaccessible released digested samples were analyzed by liquid chromatography coupled photodiode array mass spectrometry detection. anthocyanins (cyanidin-3-O-sambubioside delphinidin-3-O-sambubioside) content drastically...
The antifungal drugs currently available and mostly used for the treatment of candidiasis exhibit phenomena toxicity increasing resistance. In this context, plant materials might represent promising sources agents. aim study is to evaluate first time chemical content volatile fractions (VFs) along with anti-biofilm Convolvulus althaeoides L. roots. composition was determined by gas chromatography coupled a flame ionization detector mass spectrometry. total, 73 86 compounds were detected in...
Olive oil is an important product in the Mediterranean diet, due to its health benefits and sensorial characteristics. Picholine marocaine most cultivated variety Morocco. The present research aims evaluate phenolic compounds, vitamin E fatty acids of commercial virgin olive oils (VOOs) from five different North Moroccan provinces (Chefchaouen, Taounate, Errachidia, Beni Mellal Taza), using HPLC-photodiode array (PDA)/electrospray ionization (ESI)-MS, normal phase (NP)-HPLC/ fluorescence...
Indian mustard or Brassica juncea (B. juncea) is an oilseed plant used in many types of food (as IV range salad). It also has non-food uses (e.g., as green manure), and a good model for phytoremediation metals pesticides. In recent years, it gained special attention due to its biological compounds potential beneficial effects on human health. this study, different tissues, namely leaves, stems, roots, flowers three accessions B. juncea: ISCI 99 (Sample A), Top B), “Broad-leaf” C) were...
Scarce information about the phenolic composition of Scabiosa atropurpurea L. is available, and no carotenoid compounds have been reported thus far. In this study plant was both investigated associated bioactivities were evaluated. Aiming to obtain extracts volatile fractions known medicinal plants valorize them in pharmaceutical or food industries, two techniques extraction five solvents used determine biologically active compounds. Gas chromatography coupled flame ionization mass...
Origanum compactum belonging to the family Lamiaceae is widely used in food and pharmaceutical fields due its biologically active substances. We aimed investigate total phenol flavonoid contents phenolic composition, evaluate antioxidant antibacterial properties of hydroethanolic extract from compactum. Total were evaluated using gallic acid quercetin as standards, respectively, profile was characterized high-performance liquid chromatography coupled a photodiode array electrospray...
In continuation of research conducted on species the spontaneous flora Sicily (Italy) belonging to Brassicaceae family,
Apart from its essential oil, Prunus armeniaca L. kernel extract has received only scarce attention. The present study aimed to describe the lipid and polyphenolic composition of dichloromethane, chloroform, ethyl acetate, ethanol extracts on basis hot extraction, performing analysis by gas chromatography high-performance liquid coupled with mass spectrometry. A total 6 diacylglycerols (DAGs) 18 triacylglycerols (TAGs) were detected as being in all extracts, predominance OLL...